Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 50045945
TargetUDP-glucuronosyltransferase 1A1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50088504(CHEBI:45409 | A-84538 | ABBOTT-84538 | Norvir | Ri...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in estradiol 3-glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 1A1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50088504(CHEBI:45409 | A-84538 | ABBOTT-84538 | Norvir | Ri...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in bilirubin glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 1A1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50101979(2,6-dihydroxyanthracene-9,10-dione | anthraflavin ...)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in bilirubin glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 1A1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50101979(2,6-dihydroxyanthracene-9,10-dione | anthraflavin ...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in estradiol 3-glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 1A1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50009001(CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in estradiol 3-glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 1A1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50301375(L-thyroxine | 3,3',5,5'-tetraiodo-L-thyronine | 3,...)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in bilirubin glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 1A1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50301375(L-thyroxine | 3,3',5,5'-tetraiodo-L-thyronine | 3,...)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in estradiol 3-glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 1A1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50009001(CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in bilirubin glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 1A1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM23420(CHEMBL8145 | US8552057, 7 | 7-hydroxy-3-(4-hydroxy...)
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in bilirubin glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 1A1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM25759([3-(9H-carbazol-4-yloxy)-2-hydroxypropyl][2-(2-met...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in estradiol 3-glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 1A1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM85507(NSC_4488 | CAS_4394-00-7 | Niflumic acid (Hit 16) ...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in estradiol 3-glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 1A1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM8610(24F2-1,25(OH)D3 | Ketoconazole (k) | KTZ | 1-[4-(4...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in estradiol 3-glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 1A1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50187243(ethinyloestradiol | 17alpha-ethynylestra-1,3,5(10)...)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in bilirubin glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 1A1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM8610(24F2-1,25(OH)D3 | Ketoconazole (k) | KTZ | 1-[4-(4...)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in bilirubin glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 1A1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM25759([3-(9H-carbazol-4-yloxy)-2-hydroxypropyl][2-(2-met...)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in bilirubin glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 1A1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM11021((2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol |...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in estradiol 3-glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 1A1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50187243(ethinyloestradiol | 17alpha-ethynylestra-1,3,5(10)...)
Affinity DataIC50: 4.40E+4nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in estradiol 3-glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 1A1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM11021((2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol |...)
Affinity DataIC50: 4.70E+4nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in bilirubin glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 1A1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM85507(NSC_4488 | CAS_4394-00-7 | Niflumic acid (Hit 16) ...)
Affinity DataIC50: 5.30E+4nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in bilirubin glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 1A1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50022178(4-Methyl-7-hydroxycoumarin | 7-Hydroxy-4-methyl-2H...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in bilirubin glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 1A1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50022178(4-Methyl-7-hydroxycoumarin | 7-Hydroxy-4-methyl-2H...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in estradiol 3-glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 1A1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50088507(CHEMBL1908021 | CHEBI:63804)
Affinity DataIC50: 1.10E+5nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in estradiol 3-glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 1A1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM23420(CHEMBL8145 | US8552057, 7 | 7-hydroxy-3-(4-hydroxy...)
Affinity DataIC50: 1.20E+5nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in estradiol 3-glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 1A1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50088507(CHEMBL1908021 | CHEBI:63804)
Affinity DataIC50: 1.20E+5nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in bilirubin glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 1A1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM30705(SMR000058231 | CHEMBL744 | cid_5070 | MLS000069369...)
Affinity DataIC50: 1.60E+5nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in estradiol 3-glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 1A1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM25351(N-[2-(4-{[(4-fluorophenyl)methyl]carbamoyl}-5-hydr...)
Affinity DataIC50: 1.70E+5nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in bilirubin glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 1A1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM30705(SMR000058231 | CHEMBL744 | cid_5070 | MLS000069369...)
Affinity DataIC50: 1.80E+5nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in bilirubin glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 1A1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM25351(N-[2-(4-{[(4-fluorophenyl)methyl]carbamoyl}-5-hydr...)
Affinity DataIC50: 1.90E+5nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in estradiol 3-glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 1A1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM23450(CHEMBL122617 | Naphth-1-ol, 9 | alpha-naphthol | 1...)
Affinity DataIC50: 2.40E+5nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in bilirubin glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 1A1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM23450(CHEMBL122617 | Naphth-1-ol, 9 | alpha-naphthol | 1...)
Affinity DataIC50: 2.80E+5nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in estradiol 3-glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 1A1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50418088(7-ETHYL-10-HYDROXY-CAMPTOTHECIN)
Affinity DataIC50: 3.60E+5nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in bilirubin glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed