Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 4820
TargetSerum paraoxonase/arylesterase 1(Human)
Ataturk University

LigandPNGBDBM50316126(Cetamide | Klaron | Sulfacel-15 | SULF-15 | N-Acet...)
Affinity DataKi:  8.60E+4nM IC50: 1.80E+5nMAssay Description:The inhibitory effects of six sulfonamide derivatives was examined against the purified enzyme hPON1 and were tested in a triplicate experiment in fi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2011
Entry Details Article
PubMed
TargetSerum paraoxonase/arylesterase 1(Human)
Ataturk University

LigandPNGBDBM10860(aromatic sulfonamide compound 6 | 4-(aminomethyl)b...)
Affinity DataKi:  3.40E+5nM IC50: 1.90E+5nMAssay Description:The inhibitory effects of six sulfonamide derivatives was examined against the purified enzyme hPON1 and were tested in a triplicate experiment in fi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2011
Entry Details Article
PubMed
TargetSerum paraoxonase/arylesterase 1(Human)
Ataturk University

LigandPNGBDBM82185(Sulfosalazine, 3)
Affinity DataKi:  5.70E+5nM IC50: 2.60E+5nMAssay Description:The inhibitory effects of six sulfonamide derivatives was examined against the purified enzyme hPON1 and were tested in a triplicate experiment in fi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2011
Entry Details Article
PubMed
TargetSerum paraoxonase/arylesterase 1(Human)
Ataturk University

LigandPNGBDBM25902(4-chloro-2-[(furan-2-ylmethyl)amino]-5-sulfamoylbe...)
Affinity DataKi:  7.02E+5nM IC50: 3.60E+5nMAssay Description:The inhibitory effects of six sulfonamide derivatives was examined against the purified enzyme hPON1 and were tested in a triplicate experiment in fi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2011
Entry Details Article
PubMed
TargetSerum paraoxonase/arylesterase 1(Human)
Ataturk University

LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  7.43E+5nM IC50: 8.00E+5nMAssay Description:The inhibitory effects of six sulfonamide derivatives was examined against the purified enzyme hPON1 and were tested in a triplicate experiment in fi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2011
Entry Details Article
PubMed
TargetSerum paraoxonase/arylesterase 1(Human)
Ataturk University

LigandPNGBDBM10868(1,3,4-thiadiazole-2-sulfonamide 15 | 5-amino-1,3,4...)
Affinity DataKi:  2.00E+6nM IC50: 1.24E+6nMAssay Description:The inhibitory effects of six sulfonamide derivatives was examined against the purified enzyme hPON1 and were tested in a triplicate experiment in fi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2011
Entry Details Article
PubMed