Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50001092
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50006801(N-Hydroxy-N-[3-(quinolin-2-ylmethoxy)-phenyl]-succ...)
Affinity DataIC50: 1.40E+3nMAssay Description:Concentration that produces 50% inhibition of A-23187-stimulated radiolabeled 5-HETE and TXB2 synthesis by PMN 5-lipoxygenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50006806(C,C,C-Trifluoro-N-[3-(quinolin-2-ylmethoxy)-phenyl...)
Affinity DataIC50: 2.00E+3nMAssay Description:Concentration that produces 50% inhibition of A-23187-stimulated radiolabeled 5-HETE and TXB2 synthesis by PMN 5-lipoxygenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50006820(CHEMBL81199 | 2-[3-(1H-Tetrazol-5-ylmethyl)-phenox...)
Affinity DataIC50: 3.90E+3nMAssay Description:Concentration that produces 50% inhibition of A-23187-stimulated radiolabeled 5-HETE and TXB2 synthesis by PMN 5-lipoxygenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50006821(CHEMBL310833 | 4-Methyl-N-[3-(quinolin-2-ylmethoxy...)
Affinity DataIC50: 6.20E+3nMAssay Description:Concentration that produces 50% inhibition of A-23187-stimulated radiolabeled 5-HETE and TXB2 synthesis by PMN 5-lipoxygenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50006806(C,C,C-Trifluoro-N-[3-(quinolin-2-ylmethoxy)-phenyl...)
Affinity DataIC50: 9.10E+3nMAssay Description:Concentration for 50% inhibition of A-23187-stimulated radiolabeled 5-HETE and TXB2 synthesis by Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50006821(CHEMBL310833 | 4-Methyl-N-[3-(quinolin-2-ylmethoxy...)
Affinity DataIC50: 1.34E+4nMAssay Description:Concentration that produces 50% inhibition of A-23187-stimulated radiolabeled 5-HETE and TXB2 synthesis by Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50006813(CHEMBL79453 | N-Methoxy-2-[3-(quinolin-2-ylmethoxy...)
Affinity DataIC50: 1.42E+4nMAssay Description:Concentration that produces 50% inhibition of A-23187-stimulated radiolabeled 5-HETE and TXB2 synthesis by PMN 5-lipoxygenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50006816(1-{2-Hydroxy-3-propyl-4-[4-(1H-tetrazol-5-yl)-buto...)
Affinity DataIC50: 1.89E+4nMAssay Description:Concentration that produces 50% inhibition of A-23187-stimulated radiolabeled 5-HETE and TXB2 synthesis by PMN 5-lipoxygenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50006801(N-Hydroxy-N-[3-(quinolin-2-ylmethoxy)-phenyl]-succ...)
Affinity DataIC50: 4.04E+4nMAssay Description:Concentration that produces 50% inhibition of A-23187-stimulated radiolabeled 5-HETE and TXB2 synthesis by PMN (Prostaglandin G/H synthase).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50006816(1-{2-Hydroxy-3-propyl-4-[4-(1H-tetrazol-5-yl)-buto...)
Affinity DataIC50: 4.40E+4nMAssay Description:Concentration for 50% inhibition of A-23187-stimulated radiolabeled 5-HETE and TXB2 synthesis by Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed