Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50032612
TargetProstaglandin G/H synthase 2(Rabbit)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50331901(E-5-Bromo-3-[[4-(methylsulfonyl)phenyl]methylene]-...)
Affinity DataIC50: 100nMAssay Description:Inhibition of COX-2 in rabbit peripheral venous blood assessed as formation of 12-hydroxyheptadecatrienoic acid after 24 hrs in by HPLC presence of c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Rabbit)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50331901(E-5-Bromo-3-[[4-(methylsulfonyl)phenyl]methylene]-...)
Affinity DataIC50: 110nMAssay Description:Inhibition of COX-1 in rabbit peripheral venous blood assessed as formation of 12-hydroxyheptadecatrienoic acid after 24 hrs by HPLC in presence of c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Rabbit)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50044080(CHEMBL196996 | 2-Amino-5-[1-(3,5-di-tert-butyl-4-h...)
Affinity DataIC50: 110nMAssay Description:Inhibition of COX-2 in rabbit peripheral venous blood assessed as formation of 12-hydroxyheptadecatrienoic acid after 24 hrs in by HPLC presence of c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Rabbit)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50331895(E-5-Nitro-3-[[4-(sulfamoyl)phenyl]methylene]-indol...)
Affinity DataIC50: 140nMAssay Description:Inhibition of COX-1 in rabbit peripheral venous blood assessed as formation of 12-hydroxyheptadecatrienoic acid after 24 hrs by HPLC in presence of c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Rabbit)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50331891(E-5-Chloro-3-[[4-(sulfamoyl)phenyl]methylene]-indo...)
Affinity DataIC50: 160nMAssay Description:Inhibition of COX-1 in rabbit peripheral venous blood assessed as formation of 12-hydroxyheptadecatrienoic acid after 24 hrs by HPLC in presence of c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Rabbit)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50331890(E-5-Fluoro-3-[[4-(sulfamoyl)phenyl]methylene]-indo...)
Affinity DataIC50: 180nMAssay Description:Inhibition of COX-2 in rabbit peripheral venous blood assessed as formation of 12-hydroxyheptadecatrienoic acid after 24 hrs in by HPLC presence of c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Rabbit)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50331900(E-6-Chloro-3-[[4-(methylsulfonyl)phenyl]methylene]...)
Affinity DataIC50: 240nMAssay Description:Inhibition of COX-1 in rabbit peripheral venous blood assessed as formation of 12-hydroxyheptadecatrienoic acid after 24 hrs by HPLC in presence of c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Rabbit)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50331902(E-5-Nitro-3-[[4-(Methylsulfonyl)phenyl]methylene]-...)
Affinity DataIC50: 500nMAssay Description:Inhibition of COX-1 in rabbit peripheral venous blood assessed as formation of 12-hydroxyheptadecatrienoic acid after 24 hrs by HPLC in presence of c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Rabbit)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50331890(E-5-Fluoro-3-[[4-(sulfamoyl)phenyl]methylene]-indo...)
Affinity DataIC50: 620nMAssay Description:Inhibition of COX-1 in rabbit peripheral venous blood assessed as formation of 12-hydroxyheptadecatrienoic acid after 24 hrs by HPLC in presence of c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Rabbit)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50331900(E-6-Chloro-3-[[4-(methylsulfonyl)phenyl]methylene]...)
Affinity DataIC50: 2.39E+3nMAssay Description:Inhibition of COX-2 in rabbit peripheral venous blood assessed as formation of 12-hydroxyheptadecatrienoic acid after 24 hrs in by HPLC presence of c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Rabbit)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50331888(5-Chloro-2-oxo-3-(thiophene-2-carbonyl)-2,3-dihydr...)
Affinity DataIC50: 2.56E+3nMAssay Description:Inhibition of COX-1 in rabbit peripheral venous blood assessed as formation of 12-hydroxyheptadecatrienoic acid after 24 hrs by HPLC in presence of c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Rabbit)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50331902(E-5-Nitro-3-[[4-(Methylsulfonyl)phenyl]methylene]-...)
Affinity DataIC50: 3.29E+3nMAssay Description:Inhibition of COX-2 in rabbit peripheral venous blood assessed as formation of 12-hydroxyheptadecatrienoic acid after 24 hrs in by HPLC presence of c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Rabbit)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50331891(E-5-Chloro-3-[[4-(sulfamoyl)phenyl]methylene]-indo...)
Affinity DataIC50: 3.31E+3nMAssay Description:Inhibition of COX-2 in rabbit peripheral venous blood assessed as formation of 12-hydroxyheptadecatrienoic acid after 24 hrs in by HPLC presence of c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Rabbit)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50331895(E-5-Nitro-3-[[4-(sulfamoyl)phenyl]methylene]-indol...)
Affinity DataIC50: 3.72E+3nMAssay Description:Inhibition of COX-2 in rabbit peripheral venous blood assessed as formation of 12-hydroxyheptadecatrienoic acid after 24 hrs in by HPLC presence of c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Rabbit)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50331898(E-5-Chloro-3-[[4-(methylsulfonyl)phenyl]methylene]...)
Affinity DataIC50: 3.82E+3nMAssay Description:Inhibition of COX-2 in rabbit peripheral venous blood assessed as formation of 12-hydroxyheptadecatrienoic acid after 24 hrs in by HPLC presence of c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Rabbit)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50331896(E-3-[[4-(Methylsulfonyl)phenyl]methylene]-indolin-...)
Affinity DataIC50: 5.52E+3nMAssay Description:Inhibition of COX-2 in rabbit peripheral venous blood assessed as formation of 12-hydroxyheptadecatrienoic acid after 24 hrs in by HPLC presence of c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Rabbit)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50331888(5-Chloro-2-oxo-3-(thiophene-2-carbonyl)-2,3-dihydr...)
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of COX-2 in rabbit peripheral venous blood assessed as formation of 12-hydroxyheptadecatrienoic acid after 24 hrs in by HPLC presence of c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Rabbit)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50331897(E-5-Fluoro-3-[[4-(methylsulfonyl)phenyl]methylene]...)
Affinity DataIC50: 8.99E+3nMAssay Description:Inhibition of COX-1 in rabbit peripheral venous blood assessed as formation of 12-hydroxyheptadecatrienoic acid after 24 hrs by HPLC in presence of c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Rabbit)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50331896(E-3-[[4-(Methylsulfonyl)phenyl]methylene]-indolin-...)
Affinity DataIC50: 9.32E+3nMAssay Description:Inhibition of COX-1 in rabbit peripheral venous blood assessed as formation of 12-hydroxyheptadecatrienoic acid after 24 hrs by HPLC in presence of c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Rabbit)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50331894(E-5-Bromo-3-[[4-(sulfamoyl)phenyl]methylene]-indol...)
Affinity DataIC50: 2.09E+4nMAssay Description:Inhibition of COX-2 in rabbit peripheral venous blood assessed as formation of 12-hydroxyheptadecatrienoic acid after 24 hrs in by HPLC presence of c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Rabbit)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50331894(E-5-Bromo-3-[[4-(sulfamoyl)phenyl]methylene]-indol...)
Affinity DataIC50: 2.46E+4nMAssay Description:Inhibition of COX-1 in rabbit peripheral venous blood assessed as formation of 12-hydroxyheptadecatrienoic acid after 24 hrs by HPLC in presence of c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Rabbit)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50044080(CHEMBL196996 | 2-Amino-5-[1-(3,5-di-tert-butyl-4-h...)
Affinity DataIC50: 3.76E+4nMAssay Description:Inhibition of COX-1 in rabbit peripheral venous blood assessed as formation of 12-hydroxyheptadecatrienoic acid after 24 hrs by HPLC in presence of c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Rabbit)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50331899(E-5-Methyl-3-[[4-(methylsulfonyl)phenyl]methylene]...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of COX-2 in rabbit peripheral venous blood assessed as formation of 12-hydroxyheptadecatrienoic acid after 24 hrs in by HPLC presence of c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Rabbit)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50331889(E-3-[[4-(Sulfamoyl)phenyl]methylene]-indolin-2-one...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of COX-2 in rabbit peripheral venous blood assessed as formation of 12-hydroxyheptadecatrienoic acid after 24 hrs in by HPLC presence of c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Rabbit)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50331897(E-5-Fluoro-3-[[4-(methylsulfonyl)phenyl]methylene]...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of COX-2 in rabbit peripheral venous blood assessed as formation of 12-hydroxyheptadecatrienoic acid after 24 hrs in by HPLC presence of c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Rabbit)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50331893(E-6-Chloro-3-[[4-(sulfamoyl)phenyl]methylene]-indo...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of COX-2 in rabbit peripheral venous blood assessed as formation of 12-hydroxyheptadecatrienoic acid after 24 hrs in by HPLC presence of c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Rabbit)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50331892(E-5-Methyl-3-[[4-(sulfamoyl)phenyl]methylene]-indo...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of COX-2 in rabbit peripheral venous blood assessed as formation of 12-hydroxyheptadecatrienoic acid after 24 hrs in by HPLC presence of c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Rabbit)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50331899(E-5-Methyl-3-[[4-(methylsulfonyl)phenyl]methylene]...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of COX-1 in rabbit peripheral venous blood assessed as formation of 12-hydroxyheptadecatrienoic acid after 24 hrs by HPLC in presence of c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Rabbit)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50331898(E-5-Chloro-3-[[4-(methylsulfonyl)phenyl]methylene]...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of COX-1 in rabbit peripheral venous blood assessed as formation of 12-hydroxyheptadecatrienoic acid after 24 hrs by HPLC in presence of c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Rabbit)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50331893(E-6-Chloro-3-[[4-(sulfamoyl)phenyl]methylene]-indo...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of COX-1 in rabbit peripheral venous blood assessed as formation of 12-hydroxyheptadecatrienoic acid after 24 hrs by HPLC in presence of c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Rabbit)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50331892(E-5-Methyl-3-[[4-(sulfamoyl)phenyl]methylene]-indo...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of COX-1 in rabbit peripheral venous blood assessed as formation of 12-hydroxyheptadecatrienoic acid after 24 hrs by HPLC in presence of c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Rabbit)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50331889(E-3-[[4-(Sulfamoyl)phenyl]methylene]-indolin-2-one...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of COX-1 in rabbit peripheral venous blood assessed as formation of 12-hydroxyheptadecatrienoic acid after 24 hrs by HPLC in presence of c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed