Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50032791
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
College of Chemical and Environmental Engineering

Curated by ChEMBL
LigandPNGBDBM50334788((17beta-(N-tert-butylcarbamoyl)-4-aza-5alpha-andro...)
Affinity DataIC50: 35nMAssay Description:Inhibition of human prostate 5alpha-reductase type 2 assessed as formation dihydrotestosterone from [4-14C] testosteroneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
College of Chemical and Environmental Engineering

Curated by ChEMBL
LigandPNGBDBM50334789((4aS,4bR,10aR,10bS,12aS)-10a,12a-dimethyl-2-oxo-1,...)
Affinity DataIC50: 71nMAssay Description:Inhibition of human prostate 5alpha-reductase type 2 assessed as formation dihydrotestosterone from [4-14C] testosteroneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
College of Chemical and Environmental Engineering

Curated by ChEMBL
LigandPNGBDBM50334790((4aS,4bR,10bS,12aS)-8-hydroxy-12a-methyl-3,4,4a,4b...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human prostate 5alpha-reductase type 2 assessed as formation dihydrotestosterone from [4-14C] testosteroneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
College of Chemical and Environmental Engineering

Curated by ChEMBL
LigandPNGBDBM50334791((4aS,4bR,10bS,12aS)-12a-methyl-2-oxo-1,2,3,4,4a,4b...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human prostate 5alpha-reductase type 2 assessed as formation dihydrotestosterone from [4-14C] testosteroneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed