Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 5645
Target3-phosphoinositide-dependent protein kinase 1(Human)
Merck Research Laboratories

LigandPNGBDBM26198(Jak Inhibitor 1 | CHEMBL21156 | Compound # 2 | 4-t...)
Affinity DataEC50:  1nMAssay Description:Enzyme potency (PDK1 EC50)was determined using recombinant, purified full-length human PDK1 enzyme and AKT-Thr-308-tide as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2012
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Merck Research Laboratories

LigandPNGBDBM92402(PDK1 inhibitor, 2)
Affinity DataEC50:  9nMAssay Description:Enzyme potency (PDK1 EC50)was determined using recombinant, purified full-length human PDK1 enzyme and AKT-Thr-308-tide as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2012
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Merck Research Laboratories

LigandPNGBDBM17051(N-{3-[(5-iodo-4-{[3-(thiophen-2-ylformamido)propyl...)
Affinity DataEC50:  26nMAssay Description:Enzyme potency (PDK1 EC50)was determined using recombinant, purified full-length human PDK1 enzyme and AKT-Thr-308-tide as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2012
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Merck Research Laboratories

LigandPNGBDBM92403(PDK1 inhibitor, 4)
Affinity DataEC50:  200nMAssay Description:Enzyme potency (PDK1 EC50)was determined using recombinant, purified full-length human PDK1 enzyme and AKT-Thr-308-tide as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2012
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Merck Research Laboratories

LigandPNGBDBM92404(CHEMBL250843 | PDK1 inhibitor, 5)
Affinity DataEC50:  9nMAssay Description:Enzyme potency (PDK1 EC50)was determined using recombinant, purified full-length human PDK1 enzyme and AKT-Thr-308-tide as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2012
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Merck Research Laboratories

LigandPNGBDBM92405(PDK1 inhibitor, 6)
Affinity DataEC50:  12nMAssay Description:Enzyme potency (PDK1 EC50)was determined using recombinant, purified full-length human PDK1 enzyme and AKT-Thr-308-tide as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2012
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Merck Research Laboratories

LigandPNGBDBM92406(PDK1 inhibitor, 7)
Affinity DataEC50:  1nMAssay Description:Enzyme potency (PDK1 EC50)was determined using recombinant, purified full-length human PDK1 enzyme and AKT-Thr-308-tide as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)