Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50032758
TargetPeroxisome proliferator-activated receptor alpha(Mouse)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50334216(2-(3-(3-(2-(4-methylbenzoyl)-1H-pyrrol-1-yl)prop-1...)
Affinity DataEC50:  4.90E+3nMAssay Description:Agonist activity at mouse PPARalpha ligand binding domain expressed in COS-1 cells co-transfected with Gal4 by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50334217(5-chloro-2-(3-(2-(4-methoxybenzoyl)-4-methyl-1H-py...)
Affinity DataEC50:  1.20E+4nMAssay Description:Agonist activity at human PPARgamma ligand binding domain expressed in COS-1 cells co-transfected with Gal4 by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50334218(2-(3-(3-(2-(4-methoxybenzoyl)-1H-pyrrol-1-yl)prop-...)
Affinity DataEC50:  2.00E+3nMAssay Description:Agonist activity at human PPARgamma ligand binding domain expressed in COS-1 cells co-transfected with Gal4 by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50334219(2-(3-(3-(2-(4-methoxybenzoyl)-1H-pyrrol-1-yl)prop-...)
Affinity DataEC50:  1.90E+3nMAssay Description:Agonist activity at human PPARgamma ligand binding domain expressed in COS-1 cells co-transfected with Gal4 by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50334216(2-(3-(3-(2-(4-methylbenzoyl)-1H-pyrrol-1-yl)prop-1...)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at human PPARgamma ligand binding domain expressed in COS-1 cells co-transfected with Gal4 by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50049240((+-)-5-((4-(2-(5-ethyl-2-pyridinyl)ethoxy)phenyl)m...)
Affinity DataEC50:  390nMAssay Description:Agonist activity at human PPARgamma ligand binding domain expressed in COS-1 cells co-transfected with Gal4 by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50334217(5-chloro-2-(3-(2-(4-methoxybenzoyl)-4-methyl-1H-py...)
Affinity DataEC50: >9.00E+4nMAssay Description:Agonist activity at human PPARalpha ligand binding domain expressed in COS-1 cells co-transfected with Gal4 by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50334218(2-(3-(3-(2-(4-methoxybenzoyl)-1H-pyrrol-1-yl)prop-...)
Affinity DataEC50:  2.10E+4nMAssay Description:Agonist activity at human PPARalpha ligand binding domain expressed in COS-1 cells co-transfected with Gal4 by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM28700(alpha-1081 | procetofenic acid | Fenofibrate | CHE...)
Affinity DataEC50:  1.20E+4nMAssay Description:Agonist activity at human PPARalpha ligand binding domain expressed in COS-1 cells co-transfected with Gal4 by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor alpha(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50334219(2-(3-(3-(2-(4-methoxybenzoyl)-1H-pyrrol-1-yl)prop-...)
Affinity DataEC50:  3.70E+3nMAssay Description:Agonist activity at human PPARalpha ligand binding domain expressed in COS-1 cells co-transfected with Gal4 by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50334216(2-(3-(3-(2-(4-methylbenzoyl)-1H-pyrrol-1-yl)prop-1...)
Affinity DataEC50:  1.80E+3nMAssay Description:Agonist activity at human PPARalpha ligand binding domain expressed in COS-1 cells co-transfected with Gal4 by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed