Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50032760
TargetBile acid receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50334234((S)-2-(6-chloro-2-(4-chlorophenyl)-5-fluoro-1H-ben...)
Affinity DataIC50: 13nMAssay Description:Displacement of radioligand from human FXR by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetBile acid receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50334233(2-(2-(4-chlorophenyl)-1H-benzo[d]imidazol-1-yl)-N,...)
Affinity DataIC50: 70nMAssay Description:Displacement of radioligand from human FXR by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetBile acid receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50334234((S)-2-(6-chloro-2-(4-chlorophenyl)-5-fluoro-1H-ben...)
Affinity DataEC50:  141nMAssay Description:Agonist activity at human FXR expressed in cells assessed as transactivation by luciferase transcriptional reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetBile acid receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50334242(2-(2-(4-chlorophenyl)-1H-benzo[d]imidazol-1-yl)-2-...)
Affinity DataIC50: 150nMAssay Description:Displacement of radioligand from human FXR by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetBile acid receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50334238(2-(2-(4-chlorophenyl)-6-methoxy-1H-benzo[d]imidazo...)
Affinity DataIC50: 450nMAssay Description:Displacement of radioligand from human FXR by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetBile acid receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50334246(2-(2-(4-chlorophenyl)-1H-benzo[d]imidazol-1-yl)-N-...)
Affinity DataIC50: 910nMAssay Description:Displacement of radioligand from human FXR by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetBile acid receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50334232(2-(2-(4-cyanophenyl)-1H-benzo[d]imidazol-1-yl)-N,2...)
Affinity DataIC50: 1.25E+3nMAssay Description:Displacement of radioligand from human FXR by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetBile acid receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50334241(2-(2-(4-chlorophenyl)-1H-benzo[d]imidazol-1-yl)-2-...)
Affinity DataIC50: 2.72E+3nMAssay Description:Displacement of radioligand from human FXR by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetBile acid receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50334240(2-(2-(4-chlorophenyl)-1H-benzo[d]imidazol-1-yl)-2-...)
Affinity DataIC50: 3.61E+3nMAssay Description:Displacement of radioligand from human FXR by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetBile acid receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50334239(2-(2-(4-chlorophenyl)-1H-benzo[d]imidazol-1-yl)-2-...)
Affinity DataIC50: 3.71E+3nMAssay Description:Displacement of radioligand from human FXR by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetBile acid receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50334245(2-(2-(4-chlorophenyl)-1H-benzo[d]imidazol-1-yl)-N-...)
Affinity DataIC50: 3.80E+3nMAssay Description:Displacement of radioligand from human FXR by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetBile acid receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50334237(2-(2-(4-chlorophenyl)-6-(dimethylamino)-1H-benzo[d...)
Affinity DataIC50: 5.17E+3nMAssay Description:Displacement of radioligand from human FXR by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetBile acid receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50334236(2-(4-chlorophenyl)-1-(1-cyclohexyl-2-(cyclohexylam...)
Affinity DataIC50: 5.72E+3nMAssay Description:Displacement of radioligand from human FXR by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetBile acid receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50334235(2-(2-(4-chlorophenyl)-6-(hydroxymethyl)-1H-benzo[d...)
Affinity DataIC50: 6.19E+3nMAssay Description:Displacement of radioligand from human FXR by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetBile acid receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50334231(N,2-dicyclohexyl-2-(2-(4-(methylsulfonyl)phenyl)-1...)
Affinity DataIC50: 1.24E+4nMAssay Description:Displacement of radioligand from human FXR by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetBile acid receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50334244(2-(4-acetylpiperidin-1-yl)-2-(2-(4-chlorophenyl)-1...)
Affinity DataIC50: 1.48E+4nMAssay Description:Displacement of radioligand from human FXR by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetBile acid receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50334243(2-(2-(4-chlorophenyl)-1H-benzo[d]imidazol-1-yl)-N-...)
Affinity DataIC50: 2.51E+4nMAssay Description:Displacement of radioligand from human FXR by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetBile acid receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50334230(N,2-dicyclohexyl-2-(2-(pyridin-4-yl)-1H-benzo[d]im...)
Affinity DataIC50: 3.04E+4nMAssay Description:Displacement of radioligand from human FXR by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed