Compile Data Set for Download or QSAR
Report error Found 41 Enz. Inhib. hit(s) with all data for entry = 50041881
TargetRho-associated protein kinase 1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417683(CHEMBL1643573)
Affinity DataIC50: 240nMAssay Description:Inhibition of ROCK-1 by Immobilized metal ion affinity-based fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417667(CHEMBL1643574)
Affinity DataIC50: 240nMAssay Description:Inhibition of ROCK-1 by Immobilized metal ion affinity-based fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM14029(4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-...)
Affinity DataIC50: 245nMAssay Description:Inhibition of ROCK-2 by Immobilized metal ion affinity-based fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417687(CHEMBL1643356)
Affinity DataIC50: 427nMAssay Description:Inhibition of ROCK-1 by Immobilized metal ion affinity-based fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM14031(CHEMBL1233300 | 5-(1,4-diazepane-1-sulfonyl)-1,2-d...)
Affinity DataIC50: 575nMAssay Description:Inhibition of ROCK-2 by Immobilized metal ion affinity-based fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417678(CHEMBL1643365)
Affinity DataIC50: 575nMAssay Description:Inhibition of ROCK-1 by Immobilized metal ion affinity-based fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417670(CHEMBL1643357)
Affinity DataIC50: 589nMAssay Description:Inhibition of ROCK-1 by Immobilized metal ion affinity-based fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM14031(CHEMBL1233300 | 5-(1,4-diazepane-1-sulfonyl)-1,2-d...)
Affinity DataIC50: 759nMAssay Description:Inhibition of ROCK-1 by Immobilized metal ion affinity-based fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417671(CHEMBL1643358)
Affinity DataIC50: 776nMAssay Description:Inhibition of ROCK-1 by Immobilized metal ion affinity-based fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417672(CHEMBL1643359)
Affinity DataIC50: 813nMAssay Description:Inhibition of ROCK-1 by Immobilized metal ion affinity-based fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM14029(4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-...)
Affinity DataIC50: 871nMAssay Description:Inhibition of ROCK-1 by Immobilized metal ion affinity-based fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417673(CHEMBL1643360)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of ROCK-1 by Immobilized metal ion affinity-based fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417674(CHEMBL1643361)
Affinity DataIC50: 1.29E+3nMAssay Description:Inhibition of ROCK-2 by Immobilized metal ion affinity-based fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417674(CHEMBL1643361)
Affinity DataIC50: 1.29E+3nMAssay Description:Inhibition of ROCK-1 by Immobilized metal ion affinity-based fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM14027(AT877 | CHEMBL38380 | 5-(1,4-diazepan-1-ylsulfonyl...)
Affinity DataIC50: 1.35E+3nMAssay Description:Inhibition of ROCK-2 by Immobilized metal ion affinity-based fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetRho-associated protein kinase 1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417675(CHEMBL1643362)
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibition of ROCK-1 by Immobilized metal ion affinity-based fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417676(CHEMBL1643363)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of ROCK-1 by Immobilized metal ion affinity-based fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417677(CHEMBL1643364)
Affinity DataIC50: 1.86E+3nMAssay Description:Inhibition of ROCK-1 by Immobilized metal ion affinity-based fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417681(CHEMBL1643571)
Affinity DataIC50: 1.95E+3nMAssay Description:Inhibition of ROCK-1 by Immobilized metal ion affinity-based fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417668(CHEMBL1643368)
Affinity DataIC50: 2.14E+3nMAssay Description:Inhibition of ROCK-1 by Immobilized metal ion affinity-based fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetC-C motif chemokine 2(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM14029(4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-...)
Affinity DataIC50: 2.63E+3nMAssay Description:Inhibition of MCP1-mediated human THP cell migrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM14027(AT877 | CHEMBL38380 | 5-(1,4-diazepan-1-ylsulfonyl...)
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of ROCK-1 by Immobilized metal ion affinity-based fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetRho-associated protein kinase 1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417679(CHEMBL1643366)
Affinity DataIC50: 3.47E+3nMAssay Description:Inhibition of ROCK-1 by Immobilized metal ion affinity-based fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417682(CHEMBL1643572)
Affinity DataIC50: 3.63E+3nMAssay Description:Inhibition of ROCK-1 by Immobilized metal ion affinity-based fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417684(CHEMBL1643575)
Affinity DataIC50: 4.27E+3nMAssay Description:Inhibition of ROCK-1 by Immobilized metal ion affinity-based fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417680(CHEMBL1643367)
Affinity DataIC50: 6.76E+3nMAssay Description:Inhibition of ROCK-1 by Immobilized metal ion affinity-based fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetC-C motif chemokine 2(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM14031(CHEMBL1233300 | 5-(1,4-diazepane-1-sulfonyl)-1,2-d...)
Affinity DataIC50: 6.92E+3nMAssay Description:Inhibition of MCP1-mediated human THP cell migrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetC-C motif chemokine 2(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM14027(AT877 | CHEMBL38380 | 5-(1,4-diazepan-1-ylsulfonyl...)
Affinity DataIC50: 6.92E+3nMAssay Description:Inhibition of MCP1-mediated human THP cell migrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417669(CHEMBL1643355)
Affinity DataIC50: 7.76E+3nMAssay Description:Inhibition of ROCK-1 by Immobilized metal ion affinity-based fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetC-C motif chemokine 2(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417674(CHEMBL1643361)
Affinity DataIC50: 3.16E+4nMAssay Description:Inhibition of MCP1-mediated human THP cell migrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417685(CHEMBL1643576)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of ROCK-1 by Immobilized metal ion affinity-based fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM14029(4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-...)
Affinity DataKi:  25.1nMAssay Description:Inhibition of ROCK-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM14031(CHEMBL1233300 | 5-(1,4-diazepane-1-sulfonyl)-1,2-d...)
Affinity DataKi:  31.6nMAssay Description:Inhibition of ROCK-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417674(CHEMBL1643361)
Affinity DataKi:  63.1nMAssay Description:Inhibition of ROCK-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM14027(AT877 | CHEMBL38380 | 5-(1,4-diazepan-1-ylsulfonyl...)
Affinity DataKi:  100nMAssay Description:Inhibition of ROCK-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50417667(CHEMBL1643574)
Affinity DataKi:  794nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
LigandPNGBDBM50417674(CHEMBL1643361)
Affinity DataKi:  3.16E+3nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
LigandPNGBDBM14031(CHEMBL1233300 | 5-(1,4-diazepane-1-sulfonyl)-1,2-d...)
Affinity DataKi:  7.94E+3nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
LigandPNGBDBM50417668(CHEMBL1643368)
Affinity DataKi:  2.00E+4nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
LigandPNGBDBM14027(AT877 | CHEMBL38380 | 5-(1,4-diazepan-1-ylsulfonyl...)
Affinity DataKi:  2.51E+4nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
LigandPNGBDBM14029(4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-...)
Affinity DataKi:  7.94E+4nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed