Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50022641
Affinity DataIC50: 71nMAssay Description:Inhibition of [3H]-BTZO-1 binding to recombinant human C-terminal His-tagged MIF expressed in Escherichia coli BL21 (DE3) measured after 3 hrs by SPAMore data for this Ligand-Target Pair
Affinity DataKd: 88nMAssay Description:Binding affinity to BTZO-12 sensor chip immobilized human MIF expressed in Escherichia coli BL21 (DE3) by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 157nMAssay Description:Binding affinity to recombinant human C-terminal His-tagged MIF expressed in Escherichia coli BL21 (DE3) at 400 nM incubated for 6 hrs using labelled...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of [3H]-BTZO-1 binding to recombinant human C-terminal His-tagged MIF expressed in Escherichia coli BL21 (DE3) measured after 3 hrs by SPAMore data for this Ligand-Target Pair
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of [3H]-BTZO-1 binding to recombinant human C-terminal His-tagged MIF expressed in Escherichia coli BL21 (DE3) measured after 3 hrs by SPAMore data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Rattus norvegicus)
Takeda Pharmaceutical Co. Ltd.
Curated by ChEMBL
Takeda Pharmaceutical Co. Ltd.
Curated by ChEMBL
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of recombinant rat MIF expressed in Escherichia coli BL21 (DE3) assessed as reduction in tautomerase activity using L-dopachrome carboxy-m...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Rattus norvegicus)
Takeda Pharmaceutical Co. Ltd.
Curated by ChEMBL
Takeda Pharmaceutical Co. Ltd.
Curated by ChEMBL
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of recombinant rat MIF expressed in Escherichia coli BL21 (DE3) assessed as reduction in tautomerase activity using L-dopachrome carboxy-m...More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of [3H]-BTZO-1 binding to recombinant human C-terminal His-tagged MIF expressed in Escherichia coli BL21 (DE3) measured after 3 hrs by SPAMore data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Rattus norvegicus)
Takeda Pharmaceutical Co. Ltd.
Curated by ChEMBL
Takeda Pharmaceutical Co. Ltd.
Curated by ChEMBL
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant rat MIF expressed in Escherichia coli BL21 (DE3) assessed as reduction in tautomerase activity using L-dopachrome carboxy-m...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Rattus norvegicus)
Takeda Pharmaceutical Co. Ltd.
Curated by ChEMBL
Takeda Pharmaceutical Co. Ltd.
Curated by ChEMBL
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant rat MIF expressed in Escherichia coli BL21 (DE3) assessed as reduction in tautomerase activity using L-dopachrome carboxy-m...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Rattus norvegicus)
Takeda Pharmaceutical Co. Ltd.
Curated by ChEMBL
Takeda Pharmaceutical Co. Ltd.
Curated by ChEMBL
Affinity DataIC50: 6.80E+4nMAssay Description:Inhibition of recombinant rat MIF expressed in Escherichia coli BL21 (DE3) assessed as reduction in tautomerase activity using L-dopachrome carboxy-m...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of [3H]-BTZO-1 binding to recombinant human C-terminal His-tagged MIF expressed in Escherichia coli BL21 (DE3) measured after 3 hrs by SPAMore data for this Ligand-Target Pair
