Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50032706
TargetRibosomal protein S6 kinase beta-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50333483(1-[5-tert-Butyl-3-(1,1-dioxo-1lambda*6*-thiomorpho...)
Affinity DataIC50: 34nMAssay Description:Inhibition of S6K1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50333468(1-(5-tert-butyl-3-((2-(dimethylamino)ethyl)carbamo...)
Affinity DataIC50: 521nMAssay Description:Inhibition of S6K1 in ribosomal protein S6 by whole cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50333467(2-(3-1H-indazol-5-ylureido)-5-tert-butyl-N-cyclopr...)
Affinity DataIC50: 685nMAssay Description:Inhibition of S6K1 in ribosomal protein S6 by whole cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50333484(1-[5-tert-Butyl-3-(1,1-dioxo-1lambda*6*-thiomorpho...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of S6K1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50333473(2-(3-1H-indazol-5-ylureido)-5-tert-butyl-N-(2-meth...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of S6K1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50333489(1-[5-tert-Butyl-3-(1,1-dioxo-1lambda*6*-thiomorpho...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of S6K1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50333467(2-(3-1H-indazol-5-ylureido)-5-tert-butyl-N-cyclopr...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of S6K1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50333468(1-(5-tert-butyl-3-((2-(dimethylamino)ethyl)carbamo...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of S6K1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50333472(2-(3-1H-indazol-5-ylureido)-5-tert-butyl-N-(2-hydr...)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of S6K1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50333475(1-(5-tert-butylthiophen-2-yl)-3-(1H-indazol-5-yl)u...)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of S6K1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50333490(1-[5-tert-Butyl-3-(1,1-dioxo-1lambda*6*-thiomorpho...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of S6K1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50333488(1-Benzo[4,5]furo[3,2-b]pyridin-8-yl-3-[5-tert-buty...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of S6K1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50333487(1-[5-tert-Butyl-3-(1,1-dioxo-1lambda*6*-thiomorpho...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of S6K1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50333486(1-[5-tert-Butyl-3-(1,1-dioxo-1lambda*6*-thiomorpho...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of S6K1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50333485(1-[5-tert-Butyl-3-(1,1-dioxo-1lambda*6*-thiomorpho...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of S6K1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50333482(2-(3-1H-indazol-5-ylureido)-N-(2-(dimethylamino)et...)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of S6K1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50333474(2-(3-1H-indazol-5-ylureido)-5-tert-butylthiophene-...)
Affinity DataIC50: 5.20E+4nMAssay Description:Inhibition of S6K1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50333481(2-(3-1H-indazol-5-ylureido)-N-(2-(dimethylamino)et...)
Affinity DataIC50: 6.20E+4nMAssay Description:Inhibition of S6K1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50333480(2-(3-1H-indazol-5-ylureido)-5-cyclopropyl-N-(2-(di...)
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibition of S6K1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50333469(2-(3-1H-indazol-5-ylureido)-5-tert-butyl-N-(2-fluo...)
Affinity DataIC50: 1.91E+5nMAssay Description:Inhibition of S6K1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50333477((R)-2-(3-1H-indazol-5-ylureido)-N-(2-(dimethylamin...)
Affinity DataIC50: 1.96E+5nMAssay Description:Inhibition of S6K1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50333470(2-(3-1H-indazol-5-ylureido)-N-benzyl-5-tert-butylt...)
Affinity DataIC50: 2.01E+5nMAssay Description:Inhibition of S6K1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50333471(1-(5-tert-butyl-3-(morpholine-4-carbonyl)thiophen-...)
Affinity DataIC50: 2.07E+5nMAssay Description:Inhibition of S6K1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50333479(2-(3-1H-indazol-5-ylureido)-N-(2-(dimethylamino)et...)
Affinity DataIC50: 2.23E+5nMAssay Description:Inhibition of S6K1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50333476((S)-2-(3-1H-indazol-5-ylureido)-N-(2-(dimethylamin...)
Affinity DataIC50: 3.79E+5nMAssay Description:Inhibition of S6K1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50333478(2-(3-1H-indazol-5-ylureido)-N-(2-(dimethylamino)et...)
Affinity DataIC50: 1.90E+6nMAssay Description:Inhibition of S6K1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed