Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50032713
TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM20880(CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...)
Affinity DataIC50: 0.490nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50333628((2S,3R,4R,5S,6R)-2-(4-Chloro-3-((5-(furan-2-yl)thi...)
Affinity DataIC50: 1.75nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50333627((2S,3R,4S,5S,6R)-2-(4-chloro-3-((5-(furan-2-yl)thi...)
Affinity DataIC50: 7.01nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50333635((2S,3R,4R,5S,6S)-2-(4-chloro-3-((5-(furan-2-yl)thi...)
Affinity DataIC50: 9.55nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50333634((2S,3R,4R,5S,6S)-2-(4-chloro-3-((5-(furan-2-yl)thi...)
Affinity DataIC50: 10.6nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50333629((2S,3R,4R,5S,6R)-2-(4-chloro-3-((5-(furan-2-yl)thi...)
Affinity DataIC50: 13.5nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50333639((2S,3R,4R,5S,6S)-2-(4-chloro-3-((5-(furan-2-yl)thi...)
Affinity DataIC50: 18.6nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50333633((2S,3R,4R,5S,6R)-2-(4-chloro-3-((5-(furan-2-yl)thi...)
Affinity DataIC50: 20.8nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50333636((2S,3R,4R,5S,6R)-2-(4-chloro-3-((5-(furan-2-yl)thi...)
Affinity DataIC50: 23.5nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50333630((2S,3R,4R,5S,6R)-2-(4-chloro-3-((5-(furan-2-yl)thi...)
Affinity DataIC50: 23.8nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50333638((2S,3R,4R,5S,6R)-2-(4-chloro-3-((5-(furan-2-yl)thi...)
Affinity DataIC50: 30.9nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50333640((2S,3R,4R,5S,6S)-2-(4-chloro-3-((5-(furan-2-yl)thi...)
Affinity DataIC50: 31.9nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50333643((2S,3R,4R,5S,6S)-2-(4-chloro-3-((5-(furan-2-yl)thi...)
Affinity DataIC50: 48.9nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50333632((2S,3R,4R,5S,6R)-2-(4-chloro-3-((5-(furan-2-yl)thi...)
Affinity DataIC50: 54.8nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50333631((2S,3R,4R,5S,6R)-2-(4-chloro-3-((5-(furan-2-yl)thi...)
Affinity DataIC50: 54.9nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50333644((2S,3S,4R,5R,6S)-methyl 6-(4-chloro-3-((5-(furan-2...)
Affinity DataIC50: 59.1nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50333637((2S,3R,4R,5S,6R)-2-(4-chloro-3-((5-(furan-2-yl)thi...)
Affinity DataIC50: 68.7nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50333625((2R,3S,4R,5R,6S)-2-((1H-tetrazol-1-yl)methyl)-6-(4...)
Affinity DataIC50: 68.9nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50333642((2S,3R,4R,5S,6S)-2-(4-chloro-3-((5-(furan-2-yl)thi...)
Affinity DataIC50: 89.5nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50333626((2R,3S,4R,5R,6S)-2-((2H-tetrazol-2-yl)methyl)-6-(4...)
Affinity DataIC50: 106nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50333622(1-((2S,3S,4R,5R,6S)-6-(4-chloro-3-((5-(furan-2-yl)...)
Affinity DataIC50: 110nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50333623((2S,3R,4R,5S,6S)-2-(4-chloro-3-((5-(furan-2-yl)thi...)
Affinity DataIC50: 156nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50333624((2R,3S,4R,5R,6S)-2-((1H-1,2,4-triazol-1-yl)methyl)...)
Affinity DataIC50: 471nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50333641((2S,3R,4R,5S,6S)-2-(4-chloro-3-((5-(furan-2-yl)thi...)
Affinity DataIC50: 1.45E+3nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed