Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 50039372
TargetKappa-type opioid receptor(Human)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50378889(CHEMBL1743605)
Affinity DataEC50:  20nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50378889(CHEMBL1743605)
Affinity DataEC50:  29nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50378889(CHEMBL1743605)
Affinity DataIC50: 0.810nMAssay Description:Antagonist activity at human delta opioid receptor expressed in CHO cells assessed as inhibition of U50488-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50378890(CHEMBL1743604)
Affinity DataIC50: 1.70nMAssay Description:Antagonist activity at human delta opioid receptor expressed in CHO cells assessed as inhibition of U50488-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50378890(CHEMBL1743604)
Affinity DataIC50: 13nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50378889(CHEMBL1743605)
Affinity DataIC50: 450nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50378890(CHEMBL1743604)
Affinity DataIC50: 3.10E+3nMAssay Description:Antagonist activity at human kappa opioid receptor expressed in CHO cells assessed as inhibition of SNC80-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50378890(CHEMBL1743604)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50378889(CHEMBL1743605)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50378889(CHEMBL1743605)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50378890(CHEMBL1743604)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50324028((S)-2-((S)-2-(dimethylamino)-3-(4-hydroxy-2,6-dime...)
Affinity DataKi:  2.70nMAssay Description:Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50378889(CHEMBL1743605)
Affinity DataKi:  3.5nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50378888(CHEMBL1743603)
Affinity DataKi:  5.70nMAssay Description:Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50378890(CHEMBL1743604)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50324028((S)-2-((S)-2-(dimethylamino)-3-(4-hydroxy-2,6-dime...)
Affinity DataKi:  2.30E+3nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50378888(CHEMBL1743603)
Affinity DataKi:  4.50E+3nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50378888(CHEMBL1743603)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50324028((S)-2-((S)-2-(dimethylamino)-3-(4-hydroxy-2,6-dime...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed