Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50032890
TargetLactoylglutathione lyase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50336257(4-(3-fluorobenzylidene)-1,7-bis(4-hydroxy-3-methox...)
Affinity DataKi:  2.60E+3nMAssay Description:Inhibition of human recombinant His-tagged glyoxalase 1 expressed in Escherichia coli BL21 (DE3) preincubated for 20 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50336258(4-(4-fluorobenzylidene)-1,7-bis(4-hydroxy-3-methox...)
Affinity DataKi:  3.20E+3nMAssay Description:Inhibition of human recombinant His-tagged glyoxalase 1 expressed in Escherichia coli BL21 (DE3) preincubated for 20 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50336259(4-(5-(3,4-dimethoxyphenyl)-2-(-3-(3,4-dimethoxyphe...)
Affinity DataKi:  3.60E+3nMAssay Description:Inhibition of human recombinant His-tagged glyoxalase 1 expressed in Escherichia coli BL21 (DE3) preincubated for 20 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50336261(4-(4-hydroxy-3-methoxybenzylidene)-1,7-bis(4-hydro...)
Affinity DataKi:  3.60E+3nMAssay Description:Inhibition of human recombinant His-tagged glyoxalase 1 expressed in Escherichia coli BL21 (DE3) preincubated for 20 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50336256(4-(3,4-dimethoxybenzylidene)-1,7-bis(4-hydroxy-3-m...)
Affinity DataKi:  4.60E+3nMAssay Description:Inhibition of human recombinant His-tagged glyoxalase 1 expressed in Escherichia coli BL21 (DE3) preincubated for 20 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50336251(1,7-bis(4-fluorophenyl)-5-hydroxyhepta-1,4,6-trien...)
Affinity DataKi:  4.60E+3nMAssay Description:Inhibition of human recombinant His-tagged glyoxalase 1 expressed in Escherichia coli BL21 (DE3) preincubated for 20 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50067040(CHEMBL116438 | 1,7-bis(4-hydroxy-3-methoxyphenyl)1...)
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of human recombinant His-tagged glyoxalase 1 expressed in Escherichia coli BL21 (DE3) preincubated for 20 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50336272(Acemetacin | [1-(4-Chloro-benzoyl)-5-methoxy-2-met...)
Affinity DataKi:  1.29E+4nMAssay Description:Inhibition of glyoxalase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50059989(cid_5324473 | CHEMBL105350 | 1,7-bis(4-hydroxyphen...)
Affinity DataKi:  1.80E+4nMAssay Description:Inhibition of human recombinant His-tagged glyoxalase 1 expressed in Escherichia coli BL21 (DE3) preincubated for 20 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50336254(5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-7-(1H-pyrr...)
Affinity DataKi:  1.80E+4nMAssay Description:Inhibition of human recombinant His-tagged glyoxalase 1 expressed in Escherichia coli BL21 (DE3) preincubated for 20 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataKi:  1.81E+4nMAssay Description:Inhibition of glyoxalase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetLactoylglutathione lyase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataKi:  2.40E+4nMAssay Description:Inhibition of human recombinant His-tagged glyoxalase 1 expressed in Escherichia coli BL21 (DE3) preincubated for 20 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetLactoylglutathione lyase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50336264(3-((5-nitrofuran-2-yl)methylene)pentane-2,4-dione ...)
Affinity DataKi:  2.70E+4nMAssay Description:Inhibition of human recombinant His-tagged glyoxalase 1 expressed in Escherichia coli BL21 (DE3) preincubated for 20 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50336252(1-(3,4-dimethoxyphenyl)-5-hydroxy-7-(4-hydroxyphen...)
Affinity DataKi:  2.90E+4nMAssay Description:Inhibition of human recombinant His-tagged glyoxalase 1 expressed in Escherichia coli BL21 (DE3) preincubated for 20 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50336268(diethyl 2,5-diacetylhexa-2,4-dienedioate | CHEMBL1...)
Affinity DataKi:  3.90E+4nMAssay Description:Inhibition of human recombinant His-tagged glyoxalase 1 expressed in Escherichia coli BL21 (DE3) preincubated for 20 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50336272(Acemetacin | [1-(4-Chloro-benzoyl)-5-methoxy-2-met...)
Affinity DataKi:  4.90E+4nMAssay Description:Inhibition of human recombinant His-tagged glyoxalase 1 expressed in Escherichia coli BL21 (DE3) preincubated for 20 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50336267(ethyl 2-(3-nitrobenzylidene)-3-oxobutanoate | CHEM...)
Affinity DataKi:  6.50E+4nMAssay Description:Inhibition of human recombinant His-tagged glyoxalase 1 expressed in Escherichia coli BL21 (DE3) preincubated for 20 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50336253(5-hydroxy-7-(5-(hydroxymethyl)furan-2-yl)-1-(4-met...)
Affinity DataKi:  7.40E+4nMAssay Description:Inhibition of human recombinant His-tagged glyoxalase 1 expressed in Escherichia coli BL21 (DE3) preincubated for 20 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50012899(cis-5-Fluoro-2-methyl-1-((p-methylsulfinyl)benzyli...)
Affinity DataKi:  7.79E+4nMAssay Description:Inhibition of glyoxalase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50295287(2-(1-methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl)ace...)
Affinity DataKi:  8.78E+4nMAssay Description:Inhibition of glyoxalase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50336271(4-hydroxy-6-(4-hydroxy-3-methoxyphenyl)-hexa-3,5-d...)
Affinity DataKi:  9.00E+4nMAssay Description:Inhibition of human recombinant His-tagged glyoxalase 1 expressed in Escherichia coli BL21 (DE3) preincubated for 20 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50336263(3-(3-nitrobenzylidene)pentane-2,4-dione | CHEMBL16...)
Affinity DataKi:  9.10E+4nMAssay Description:Inhibition of human recombinant His-tagged glyoxalase 1 expressed in Escherichia coli BL21 (DE3) preincubated for 20 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50027952(CHEMBL19490 | Zomepirac | 5-(4-chlorobenzoyl)-1,4-...)
Affinity DataKi:  1.07E+5nMAssay Description:Inhibition of glyoxalase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50336260(4-(hydroxymethylene)-1,7-bis(4-methoxyphenyl)hepta...)
Affinity DataKi:  1.09E+5nMAssay Description:Inhibition of human recombinant His-tagged glyoxalase 1 expressed in Escherichia coli BL21 (DE3) preincubated for 20 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50012899(cis-5-Fluoro-2-methyl-1-((p-methylsulfinyl)benzyli...)
Affinity DataKi:  1.39E+5nMAssay Description:Inhibition of human recombinant His-tagged glyoxalase 1 expressed in Escherichia coli BL21 (DE3) preincubated for 20 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50336266(ethyl 2-(4-nitrobenzylidene)-3-oxobutanoate | CHEM...)
Affinity DataKi:  1.59E+5nMAssay Description:Inhibition of human recombinant His-tagged glyoxalase 1 expressed in Escherichia coli BL21 (DE3) preincubated for 20 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50027952(CHEMBL19490 | Zomepirac | 5-(4-chlorobenzoyl)-1,4-...)
Affinity DataKi:  3.35E+5nMAssay Description:Inhibition of human recombinant His-tagged glyoxalase 1 expressed in Escherichia coli BL21 (DE3) preincubated for 20 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM54705(calcium;2-(3-phenoxyphenyl)propanoic acid;hydrate ...)
Affinity DataKi:  3.83E+5nMAssay Description:Inhibition of human recombinant His-tagged glyoxalase 1 expressed in Escherichia coli BL21 (DE3) preincubated for 20 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50336262(3-(4-methoxybenzylidene)pentane-2,4-dione | CHEMBL...)
Affinity DataKi:  3.83E+5nMAssay Description:Inhibition of human recombinant His-tagged glyoxalase 1 expressed in Escherichia coli BL21 (DE3) preincubated for 20 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50297424(Ethyl ferulate | (E)-3-(4-Hydroxy-3-methoxy-phenyl...)
Affinity DataKi:  3.85E+5nMAssay Description:Inhibition of human recombinant His-tagged glyoxalase 1 expressed in Escherichia coli BL21 (DE3) preincubated for 20 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM54705(calcium;2-(3-phenoxyphenyl)propanoic acid;hydrate ...)
Affinity DataKi:  4.00E+5nMAssay Description:Inhibition of glyoxalase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50022271(2-(3-benzoylphenyl)propanoic acid | 2-(3-Benzoylph...)
Affinity DataKi:  4.14E+5nMAssay Description:Inhibition of glyoxalase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50336265(2-(3-nitrobenzylidene)malonic acid | CHEMBL1669735)
Affinity DataKi:  4.26E+5nMAssay Description:Inhibition of human recombinant His-tagged glyoxalase 1 expressed in Escherichia coli BL21 (DE3) preincubated for 20 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50022271(2-(3-benzoylphenyl)propanoic acid | 2-(3-Benzoylph...)
Affinity DataKi:  8.43E+5nMAssay Description:Inhibition of human recombinant His-tagged glyoxalase 1 expressed in Escherichia coli BL21 (DE3) preincubated for 20 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50295287(2-(1-methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl)ace...)
Affinity DataKi:  1.01E+6nMAssay Description:Inhibition of human recombinant His-tagged glyoxalase 1 expressed in Escherichia coli BL21 (DE3) preincubated for 20 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50336270(3-(4-fluorophenyl)acrylamide | CHEMBL1669739)
Affinity DataKi:  1.39E+6nMAssay Description:Inhibition of human recombinant His-tagged glyoxalase 1 expressed in Escherichia coli BL21 (DE3) preincubated for 20 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50336255(1,7-di(furan-2-yl)-5-hydroxyhepta-1,4,6-trien-3-on...)
Affinity DataKi:  1.50E+6nMAssay Description:Inhibition of human recombinant His-tagged glyoxalase 1 expressed in Escherichia coli BL21 (DE3) preincubated for 20 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50336269(methyl 3-(4-fluorophenyl)acrylate | CHEMBL1669711)
Affinity DataKi:  1.91E+6nMAssay Description:Inhibition of human recombinant His-tagged glyoxalase 1 expressed in Escherichia coli BL21 (DE3) preincubated for 20 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed