Compile Data Set for Download or QSAR
Report error Found 44 Enz. Inhib. hit(s) with all data for entry = 50041888
TargetRho-associated protein kinase 1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417851(CHEMBL1667977)
Affinity DataIC50: 31.6nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417843(CHEMBL1667967)
Affinity DataIC50: 38.9nMAssay Description:Inhibition of ROCK2 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417853(CHEMBL1667975)
Affinity DataIC50: 47.9nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417847(CHEMBL1667970)
Affinity DataIC50: 57.5nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417843(CHEMBL1667967)
Affinity DataIC50: 61.7nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417858(CHEMBL1667966)
Affinity DataIC50: 72.4nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417842(CHEMBL1667965)
Affinity DataIC50: 79.4nMAssay Description:Inhibition of ROCK2 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
LigandPNGBDBM50417843(CHEMBL1667967)
Affinity DataIC50: 79.4nMAssay Description:Inhibition of human PrkX by RFBA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417849(CHEMBL1667979)
Affinity DataIC50: 81.3nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417667(CHEMBL1643574)
Affinity DataIC50: 91.2nMAssay Description:Inhibition of ROCK2 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417850(CHEMBL1667978)
Affinity DataIC50: 120nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417848(CHEMBL1667980)
Affinity DataIC50: 166nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417842(CHEMBL1667965)
Affinity DataIC50: 170nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417857(CHEMBL1667969)
Affinity DataIC50: 186nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417852(CHEMBL1667976)
Affinity DataIC50: 229nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417667(CHEMBL1643574)
Affinity DataIC50: 240nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417843(CHEMBL1667967)
Affinity DataIC50: 251nMAssay Description:Inhibition of ROCK1 by RFBA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetProtein kinase C delta type(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417843(CHEMBL1667967)
Affinity DataIC50: 316nMAssay Description:Inhibition of human PKCdelta by RFBA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417842(CHEMBL1667965)
Affinity DataIC50: 331nMAssay Description:Inhibition of ROCK1 in human THP cells assessed as inhibition of MCP1-induced cell migrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417847(CHEMBL1667970)
Affinity DataIC50: 331nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetProtein kinase C epsilon type(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417843(CHEMBL1667967)
Affinity DataIC50: 398nMAssay Description:Inhibition of human PKCeta by RFBA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase D1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417843(CHEMBL1667967)
Affinity DataIC50: 501nMAssay Description:Inhibition of human PKCmu by RFBA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417856(CHEMBL1667972)
Affinity DataIC50: 525nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417844(CHEMBL1667963)
Affinity DataIC50: 575nMAssay Description:Inhibition of ROCK2 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417854(CHEMBL1667974)
Affinity DataIC50: 589nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417843(CHEMBL1667967)
Affinity DataIC50: 661nMAssay Description:Inhibition of ROCK1 in human THP cells assessed as inhibition of MCP1-induced cell migrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417846(CHEMBL1667968)
Affinity DataIC50: 676nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417844(CHEMBL1667963)
Affinity DataIC50: 759nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417667(CHEMBL1643574)
Affinity DataIC50: 776nMAssay Description:Inhibition of ROCK1 in human THP cells assessed as inhibition of MCP1-induced cell migrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417855(CHEMBL1667973)
Affinity DataIC50: 871nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417668(CHEMBL1643368)
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibition of ROCK2 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417845(CHEMBL1667964)
Affinity DataIC50: 1.78E+3nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417668(CHEMBL1643368)
Affinity DataIC50: 2.14E+3nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417844(CHEMBL1667963)
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of ROCK1 by RFBA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417668(CHEMBL1643368)
Affinity DataIC50: 5.01E+3nMAssay Description:Inhibition of ROCK1 in human THP cells assessed as inhibition of MCP1-induced cell migrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
LigandPNGBDBM50417844(CHEMBL1667963)
Affinity DataIC50: 6.31E+3nMAssay Description:Inhibition of human PrkX by RFBA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417844(CHEMBL1667963)
Affinity DataIC50: 6.92E+3nMAssay Description:Inhibition of ROCK1 in human THP cells assessed as inhibition of MCP1-induced cell migrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase D1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417844(CHEMBL1667963)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PKCmu by RFBA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetProtein kinase C epsilon type(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417844(CHEMBL1667963)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human PKCeta by RFBA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetProtein kinase C delta type(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417844(CHEMBL1667963)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of human PKCdelta by RFBA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417843(CHEMBL1667967)
Affinity DataKi:  2.51nMAssay Description:Binding affinity to ROCK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417844(CHEMBL1667963)
Affinity DataKi:  34.7nMAssay Description:Binding affinity to ROCK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417668(CHEMBL1643368)
Affinity DataKi:  37.1nMAssay Description:Binding affinity to ROCK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
LigandPNGBDBM50417843(CHEMBL1667967)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]-dofetilide from human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed