Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 50033084
TargetE3 ubiquitin-protein ligase Mdm2(Human)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50339166(CHEMBL1689398)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of human GST-tagged Mdm2 expressed in Escherichia coli harboring integrated p53-Mmd2 protein assessed as blockade of enzyme-p53 interactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50339171(CHEMBL1689403)
Affinity DataIC50: 14nMAssay Description:Inhibition of human GST-tagged Mdm2 expressed in Escherichia coli harboring integrated p53-Mmd2 protein assessed as blockade of enzyme-p53 interactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50339167(N-((4S,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S)-16-...)
Affinity DataIC50: 15nMAssay Description:Inhibition of human GST-tagged Mdm2 expressed in Escherichia coli harboring integrated p53-Mmd2 protein assessed as blockade of enzyme-p53 interactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50339168(CHEMBL1689400)
Affinity DataIC50: 18nMAssay Description:Inhibition of human GST-tagged Mdm2 expressed in Escherichia coli harboring integrated p53-Mmd2 protein assessed as blockade of enzyme-p53 interactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50339170(CHEMBL1689402)
Affinity DataIC50: 28nMAssay Description:Inhibition of human GST-tagged Mdm2 expressed in Escherichia coli harboring integrated p53-Mmd2 protein assessed as blockade of enzyme-p53 interactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50339173((2S,5S,8S,11S,14S,17S,20S,23S,26S)-23-((1H-imidazo...)
Affinity DataIC50: 28nMAssay Description:Inhibition of human GST-tagged Mdm2 expressed in Escherichia coli harboring integrated p53-Mmd2 protein assessed as blockade of enzyme-p53 interactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50339169(N-((4S,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S)-22-...)
Affinity DataIC50: 39nMAssay Description:Inhibition of human GST-tagged Mdm2 expressed in Escherichia coli harboring integrated p53-Mmd2 protein assessed as blockade of enzyme-p53 interactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50339161((2S,5S,8S,11S,14S,17S,20S,23S,26S)-23-((1H-imidazo...)
Affinity DataIC50: 44nMAssay Description:Inhibition of human GST-tagged Mdm2 expressed in Escherichia coli harboring integrated p53-Mmd2 protein assessed as blockade of enzyme-p53 interactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50339162((2S)-2-((8S,11S,14S,17S,20S)-17-((1H-imidazol-5-yl...)
Affinity DataIC50: 61nMAssay Description:Inhibition of human GST-tagged Mdm2 expressed in Escherichia coli harboring integrated p53-Mmd2 protein assessed as blockade of enzyme-p53 interactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50339163(N-((4S,7S,10S,13S,16S,19S,22S,25S)-16-((1H-imidazo...)
Affinity DataIC50: 71nMAssay Description:Inhibition of human GST-tagged Mdm2 expressed in Escherichia coli harboring integrated p53-Mmd2 protein assessed as blockade of enzyme-p53 interactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50339174((2S,5S,8S,11S,14S,17S,20S,23S,26S)-17-((1H-indol-3...)
Affinity DataIC50: 77nMAssay Description:Inhibition of human GST-tagged Mdm2 expressed in Escherichia coli harboring integrated p53-Mmd2 protein assessed as blockade of enzyme-p53 interactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetProtein Mdm4(Human)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50339176(CHEMBL1689406)
Affinity DataIC50: 100nMAssay Description:Inhibition of human GST-tagged MDMX expressed in Escherichia coli harboring integrated p53-Hmd2 protein assessed as blockade of enzyme-p53 interactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50339164(N-((4S,7S,10S,13S,16S,19S,22S,25S)-16-((1H-imidazo...)
Affinity DataIC50: 160nMAssay Description:Inhibition of human GST-tagged Mdm2 expressed in Escherichia coli harboring integrated p53-Mmd2 protein assessed as blockade of enzyme-p53 interactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50339165((2S,5S,8S,11S,14S,17S,20S,23S,26S)-17-((1H-indol-3...)
Affinity DataIC50: 170nMAssay Description:Inhibition of human GST-tagged Mdm2 expressed in Escherichia coli harboring integrated p53-Mmd2 protein assessed as blockade of enzyme-p53 interactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetProtein Mdm4(Human)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50339177((2S,5S,8S,11S,14S,17S,20S,23S,26S)-23-((1H-imidazo...)
Affinity DataIC50: 170nMAssay Description:Inhibition of human GST-tagged MDMX expressed in Escherichia coli harboring integrated p53-Hmd2 protein assessed as blockade of enzyme-p53 interactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetProtein Mdm4(Human)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50339178((2S,5S,8S,11S,14S,17S,20S,23S,26S)-23-((1H-imidazo...)
Affinity DataIC50: 180nMAssay Description:Inhibition of human GST-tagged MDMX expressed in Escherichia coli harboring integrated p53-Hmd2 protein assessed as blockade of enzyme-p53 interactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetProtein Mdm4(Human)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50339168(CHEMBL1689400)
Affinity DataIC50: 210nMAssay Description:Inhibition of human GST-tagged MDMX expressed in Escherichia coli harboring integrated p53-Hmd2 protein assessed as blockade of enzyme-p53 interactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetProtein Mdm4(Human)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50339163(N-((4S,7S,10S,13S,16S,19S,22S,25S)-16-((1H-imidazo...)
Affinity DataIC50: 220nMAssay Description:Inhibition of human GST-tagged MDMX expressed in Escherichia coli harboring integrated p53-Hmd2 protein assessed as blockade of enzyme-p53 interactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetProtein Mdm4(Human)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50339167(N-((4S,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S)-16-...)
Affinity DataIC50: 240nMAssay Description:Inhibition of human GST-tagged MDMX expressed in Escherichia coli harboring integrated p53-Hmd2 protein assessed as blockade of enzyme-p53 interactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetProtein Mdm4(Human)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50339179((8S,11S,14S,17S,20S,23S,26S,29S)-26-((1H-imidazol-...)
Affinity DataIC50: 270nMAssay Description:Inhibition of human GST-tagged MDMX expressed in Escherichia coli harboring integrated p53-Hmd2 protein assessed as blockade of enzyme-p53 interactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetProtein Mdm4(Human)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50339174((2S,5S,8S,11S,14S,17S,20S,23S,26S)-17-((1H-indol-3...)
Affinity DataIC50: 282nMAssay Description:Inhibition of human GST-tagged MDMX expressed in Escherichia coli harboring integrated p53-Hmd2 protein assessed as blockade of enzyme-p53 interactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetProtein Mdm4(Human)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50339166(CHEMBL1689398)
Affinity DataIC50: 340nMAssay Description:Inhibition of human GST-tagged MDMX expressed in Escherichia coli harboring integrated p53-Hmd2 protein assessed as blockade of enzyme-p53 interactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetProtein Mdm4(Human)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50339164(N-((4S,7S,10S,13S,16S,19S,22S,25S)-16-((1H-imidazo...)
Affinity DataIC50: 390nMAssay Description:Inhibition of human GST-tagged MDMX expressed in Escherichia coli harboring integrated p53-Hmd2 protein assessed as blockade of enzyme-p53 interactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetProtein Mdm4(Human)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50339170(CHEMBL1689402)
Affinity DataIC50: 410nMAssay Description:Inhibition of human GST-tagged MDMX expressed in Escherichia coli harboring integrated p53-Hmd2 protein assessed as blockade of enzyme-p53 interactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetProtein Mdm4(Human)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50339162((2S)-2-((8S,11S,14S,17S,20S)-17-((1H-imidazol-5-yl...)
Affinity DataIC50: 540nMAssay Description:Inhibition of human GST-tagged MDMX expressed in Escherichia coli harboring integrated p53-Hmd2 protein assessed as blockade of enzyme-p53 interactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetProtein Mdm4(Human)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50339169(N-((4S,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S)-22-...)
Affinity DataIC50: 550nMAssay Description:Inhibition of human GST-tagged MDMX expressed in Escherichia coli harboring integrated p53-Hmd2 protein assessed as blockade of enzyme-p53 interactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetProtein Mdm4(Human)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50339161((2S,5S,8S,11S,14S,17S,20S,23S,26S)-23-((1H-imidazo...)
Affinity DataIC50: 550nMAssay Description:Inhibition of human GST-tagged MDMX expressed in Escherichia coli harboring integrated p53-Hmd2 protein assessed as blockade of enzyme-p53 interactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50229787(CHEMBL191334 | 4-((4S,5R)-4,5-bis(4-chlorophenyl)-...)
Affinity DataIC50: 600nMAssay Description:Inhibition of human GST-tagged Mdm2 expressed in Escherichia coli harboring integrated p53-Mmd2 protein assessed as blockade of enzyme-p53 interactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProtein Mdm4(Human)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50339171(CHEMBL1689403)
Affinity DataIC50: 810nMAssay Description:Inhibition of human GST-tagged MDMX expressed in Escherichia coli harboring integrated p53-Hmd2 protein assessed as blockade of enzyme-p53 interactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetProtein Mdm4(Human)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50339173((2S,5S,8S,11S,14S,17S,20S,23S,26S)-23-((1H-imidazo...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human GST-tagged MDMX expressed in Escherichia coli harboring integrated p53-Hmd2 protein assessed as blockade of enzyme-p53 interactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetProtein Mdm4(Human)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50339165((2S,5S,8S,11S,14S,17S,20S,23S,26S)-17-((1H-indol-3...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human GST-tagged MDMX expressed in Escherichia coli harboring integrated p53-Hmd2 protein assessed as blockade of enzyme-p53 interactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50339175((2S,5S,8S,11S,14S,17S,20S,23S,26S)-23-((1H-imidazo...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human GST-tagged Mdm2 expressed in Escherichia coli harboring integrated p53-Mmd2 protein assessed as blockade of enzyme-p53 interactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50339172(N3-((4S,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S)-22...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human GST-tagged Mdm2 expressed in Escherichia coli harboring integrated p53-Mmd2 protein assessed as blockade of enzyme-p53 interactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetProtein Mdm4(Human)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50339175((2S,5S,8S,11S,14S,17S,20S,23S,26S)-23-((1H-imidazo...)
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of human GST-tagged MDMX expressed in Escherichia coli harboring integrated p53-Hmd2 protein assessed as blockade of enzyme-p53 interactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetProtein Mdm4(Human)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50339172(N3-((4S,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S)-22...)
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of human GST-tagged MDMX expressed in Escherichia coli harboring integrated p53-Hmd2 protein assessed as blockade of enzyme-p53 interactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed