Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50032981
TargetTyrosine-protein kinase JAK2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337332(2-(4-chlorophenyl)-1-(4-(4-(5-methyl-1H-pyrazol-3-...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337333(2-(4-fluorophenyl)-1-(4-(4-(5-methyl-1H-pyrazol-3-...)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337334(2-(4-chloro-2,6-difluorophenyl)-1-(4-(4-(5-methyl-...)
Affinity DataIC50: 1nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337336(1-(4-(4-(5-methyl-1H-pyrazol-3-ylamino)pyrrolo[1,2...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337335((4-(4-(5-methyl-1H-pyrazol-3-ylamino)pyrrolo[1,2-f...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337337(2-(4-methoxyphenyl)-1-(4-(4-(5-methyl-1H-pyrazol-3...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337338(2-(2,6-difluoro-4-methoxyphenyl)-1-(4-(4-(5-methyl...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337339(1-(4-(4-(5-methyl-1H-pyrazol-3-ylamino)pyrrolo[1,2...)
Affinity DataIC50: 2nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337340((2-bromophenyl)(4-(4-(5-methyl-1H-pyrazol-3-ylamin...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337341((4-(4-(5-methyl-1H-pyrazol-3-ylamino)pyrrolo[1,2-f...)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337342(2-(2,6-difluorophenyl)-1-(4-(4-(5-methyl-1H-pyrazo...)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337343(1-(4-(4-(5-methyl-1H-pyrazol-3-ylamino)pyrrolo[1,2...)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337344((4-(4-(5-methyl-1H-pyrazol-3-ylamino)pyrrolo[1,2-f...)
Affinity DataIC50: 3nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337345((2-methoxyphenyl)(4-(4-(5-methyl-1H-pyrazol-3-ylam...)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337346((4-(4-(5-methyl-1H-pyrazol-3-ylamino)pyrrolo[1,2-f...)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337347(2-(2-fluorophenyl)-1-(4-(4-(5-methyl-1H-pyrazol-3-...)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337348(4-(4-(4-(5-methyl-1H-pyrazol-3-ylamino)pyrrolo[1,2...)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337349(1-(4-(4-(5-methyl-1H-pyrazol-3-ylamino)pyrrolo[1,2...)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337350(2-(4-(4-(5-methyl-1H-pyrazol-3-ylamino)pyrrolo[1,2...)
Affinity DataIC50: 6nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337351((2-chlorophenyl)(4-(4-(5-methyl-1H-pyrazol-3-ylami...)
Affinity DataIC50: 7.30nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337352(N,N-dimethyl-4-(4-(5-methyl-1H-pyrazol-3-ylamino)p...)
Affinity DataIC50: 9.30nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337353(1-(4-(4-(5-(1-methylcyclopropyl)-1H-pyrazol-3-ylam...)
Affinity DataIC50: 22nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337354(1-(4-(4-(5-methyl-1H-pyrazol-3-ylamino)pyrrolo[1,2...)
Affinity DataIC50: 22nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337355(N-(5-methyl-1H-pyrazol-3-yl)-2-(piperazin-1-yl)pyr...)
Affinity DataIC50: 31nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337356(2-phenyl-1-(4-(4-(thiazol-2-ylamino)pyrrolo[1,2-f]...)
Affinity DataIC50: 59nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337357(1-(4-(4-(1-isopropyl-1H-imidazol-4-ylamino)pyrrolo...)
Affinity DataIC50: 110nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337358(2-phenyl-1-(4-(4-(pyridin-2-ylamino)pyrrolo[1,2-f]...)
Affinity DataIC50: 190nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337359(N-cyclopropyl-3-(2-(4-(2-phenylacetyl)piperazin-1-...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337331(1-(4-(4-(5-methyl-1,3,4-thiadiazol-2-ylamino)pyrro...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337331(1-(4-(4-(5-methyl-1,3,4-thiadiazol-2-ylamino)pyrro...)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of JAK3 after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed