Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 50032989
TargetGlycogen synthase kinase-3 beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337557((S)-6-(2-(2-methoxyphenyl)morpholino)-1-methyl-4-(...)
Affinity DataIC50: 6.10nMAssay Description:Inhibition of human recombinant GSK3-beta expressed in baculovirus infected SF9 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337556(6-(4-hydroxy-4-phenylpiperidin-1-yl)-1-methyl-4-(p...)
Affinity DataIC50: 8.5nMAssay Description:Inhibition of human recombinant GSK3-beta expressed in baculovirus infected SF9 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50272192(4-(4-hydroxy-3-methylphenyl)-6-phenylpyrimidin-2(1...)
Affinity DataIC50: 17.2nMAssay Description:Inhibition of human recombinant GSK3-beta expressed in baculovirus infected SF9 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337548(6-(2-methoxyphenethylamino)-1-methyl-4-(pyrimidin-...)
Affinity DataIC50: 17.4nMAssay Description:Inhibition of human recombinant GSK3-beta expressed in baculovirus infected SF9 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337544(6-(diethylamino)-1-methyl-4-(pyrimidin-4-yl)pyridi...)
Affinity DataIC50: 50.1nMAssay Description:Inhibition of human recombinant GSK3-beta expressed in baculovirus infected SF9 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337555(6-(4-(2-methoxyphenyl)piperidin-1-yl)-1-methyl-4-(...)
Affinity DataIC50: 51nMAssay Description:Inhibition of human recombinant GSK3-beta expressed in baculovirus infected SF9 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337545(1-methyl-6-(piperidin-1-yl)-4-(pyrimidin-4-yl)pyri...)
Affinity DataIC50: 62nMAssay Description:Inhibition of human recombinant GSK3-beta expressed in baculovirus infected SF9 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337558((R)-6-(2-(2-methoxyphenyl)morpholino)-1-methyl-4-(...)
Affinity DataIC50: 62.8nMAssay Description:Inhibition of human recombinant GSK3-beta expressed in baculovirus infected SF9 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337554(6-(3-(2-methoxyphenyl)piperidin-1-yl)-1-methyl-4-(...)
Affinity DataIC50: 84.1nMAssay Description:Inhibition of human recombinant GSK3-beta expressed in baculovirus infected SF9 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337559(1-methyl-6-(3-phenylpiperidin-1-yl)-4-(pyrimidin-4...)
Affinity DataIC50: 115nMAssay Description:Inhibition of human recombinant GSK3-beta expressed in baculovirus infected SF9 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337553(6-((2-methoxyphenethyl)(methyl)amino)-1-methyl-4-(...)
Affinity DataIC50: 133nMAssay Description:Inhibition of human recombinant GSK3-beta expressed in baculovirus infected SF9 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50272192(4-(4-hydroxy-3-methylphenyl)-6-phenylpyrimidin-2(1...)
Affinity DataIC50: 210nMAssay Description:Inhibition of CLK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337546(1-methyl-6-morpholino-4-(pyrimidin-4-yl)pyridin-2(...)
Affinity DataIC50: 233nMAssay Description:Inhibition of human recombinant GSK3-beta expressed in baculovirus infected SF9 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337551(6-(2-methoxybenzylamino)-1-methyl-4-(pyrimidin-4-y...)
Affinity DataIC50: 252nMAssay Description:Inhibition of human recombinant GSK3-beta expressed in baculovirus infected SF9 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337552(6-(3-(2-methoxyphenyl)propylamino)-1-methyl-4-(pyr...)
Affinity DataIC50: 260nMAssay Description:Inhibition of human recombinant GSK3-beta expressed in baculovirus infected SF9 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337549(6-(3-methoxyphenethylamino)-1-methyl-4-(pyrimidin-...)
Affinity DataIC50: 401nMAssay Description:Inhibition of human recombinant GSK3-beta expressed in baculovirus infected SF9 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337547(1-methyl-6-(phenethylamino)-4-(pyrimidin-4-yl)pyri...)
Affinity DataIC50: 592nMAssay Description:Inhibition of human recombinant GSK3-beta expressed in baculovirus infected SF9 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337556(6-(4-hydroxy-4-phenylpiperidin-1-yl)-1-methyl-4-(p...)
Affinity DataIC50: 610nMAssay Description:Inhibition of human GSK3-beta expressed in CHO AA8 cells co-expressing human tau protein after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337550(6-(4-methoxyphenethylamino)-1-methyl-4-(pyrimidin-...)
Affinity DataIC50: 731nMAssay Description:Inhibition of human recombinant GSK3-beta expressed in baculovirus infected SF9 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337548(6-(2-methoxyphenethylamino)-1-methyl-4-(pyrimidin-...)
Affinity DataIC50: 800nMAssay Description:Inhibition of human GSK3-beta expressed in CHO AA8 cells co-expressing human tau protein after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337557((S)-6-(2-(2-methoxyphenyl)morpholino)-1-methyl-4-(...)
Affinity DataIC50: 840nMAssay Description:Inhibition of human GSK3-beta expressed in CHO AA8 cells co-expressing human tau protein after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337543(1-methyl-6-phenyl-4-(pyrimidin-4-yl)pyridin-2(1H)-...)
Affinity DataIC50: 894nMAssay Description:Inhibition of human recombinant GSK3-beta expressed in baculovirus infected SF9 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337545(1-methyl-6-(piperidin-1-yl)-4-(pyrimidin-4-yl)pyri...)
Affinity DataIC50: 910nMAssay Description:Inhibition of human GSK3-beta expressed in CHO AA8 cells co-expressing human tau protein after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337558((R)-6-(2-(2-methoxyphenyl)morpholino)-1-methyl-4-(...)
Affinity DataIC50: 1.53E+3nMAssay Description:Inhibition of human GSK3-beta expressed in CHO AA8 cells co-expressing human tau protein after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337553(6-((2-methoxyphenethyl)(methyl)amino)-1-methyl-4-(...)
Affinity DataIC50: 1.69E+3nMAssay Description:Inhibition of human GSK3-beta expressed in CHO AA8 cells co-expressing human tau protein after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337544(6-(diethylamino)-1-methyl-4-(pyrimidin-4-yl)pyridi...)
Affinity DataIC50: 2.21E+3nMAssay Description:Inhibition of human GSK3-beta expressed in CHO AA8 cells co-expressing human tau protein after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337554(6-(3-(2-methoxyphenyl)piperidin-1-yl)-1-methyl-4-(...)
Affinity DataIC50: 2.32E+3nMAssay Description:Inhibition of human GSK3-beta expressed in CHO AA8 cells co-expressing human tau protein after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337555(6-(4-(2-methoxyphenyl)piperidin-1-yl)-1-methyl-4-(...)
Affinity DataIC50: 3.21E+3nMAssay Description:Inhibition of human GSK3-beta expressed in CHO AA8 cells co-expressing human tau protein after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337559(1-methyl-6-(3-phenylpiperidin-1-yl)-4-(pyrimidin-4...)
Affinity DataIC50: 4.64E+3nMAssay Description:Inhibition of human GSK3-beta expressed in CHO AA8 cells co-expressing human tau protein after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337546(1-methyl-6-morpholino-4-(pyrimidin-4-yl)pyridin-2(...)
Affinity DataIC50: 5.04E+3nMAssay Description:Inhibition of human GSK3-beta expressed in CHO AA8 cells co-expressing human tau protein after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50272192(4-(4-hydroxy-3-methylphenyl)-6-phenylpyrimidin-2(1...)
Affinity DataIC50: 5.28E+3nMAssay Description:Inhibition of human GSK3-beta expressed in CHO AA8 cells co-expressing human tau protein after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337549(6-(3-methoxyphenethylamino)-1-methyl-4-(pyrimidin-...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human GSK3-beta expressed in CHO AA8 cells co-expressing human tau protein after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337551(6-(2-methoxybenzylamino)-1-methyl-4-(pyrimidin-4-y...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human GSK3-beta expressed in CHO AA8 cells co-expressing human tau protein after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337550(6-(4-methoxyphenethylamino)-1-methyl-4-(pyrimidin-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human GSK3-beta expressed in CHO AA8 cells co-expressing human tau protein after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337547(1-methyl-6-(phenethylamino)-4-(pyrimidin-4-yl)pyri...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human GSK3-beta expressed in CHO AA8 cells co-expressing human tau protein after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337543(1-methyl-6-phenyl-4-(pyrimidin-4-yl)pyridin-2(1H)-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human GSK3-beta expressed in CHO AA8 cells co-expressing human tau protein after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337552(6-(3-(2-methoxyphenyl)propylamino)-1-methyl-4-(pyr...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human GSK3-beta expressed in CHO AA8 cells co-expressing human tau protein after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed