Compile Data Set for Download or QSAR
Report error Found 91 Enz. Inhib. hit(s) with all data for entry = 50033096
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50229787(CHEMBL191334 | 4-((4S,5R)-4,5-bis(4-chlorophenyl)-...)
Affinity DataIC50: 61nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339398((+)-R-3-(4-Chlorophenyl)-3-(1-hydroxymethylcyclopr...)
Affinity DataIC50: 170nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339369((+/-)-3-(4-chlorophenyl)-3-((1-(hydroxymethyl)cycl...)
Affinity DataIC50: 230nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339371((+/-)-trans-3-(4-Chlorophenyl)-3-(4-hydroxycyclohe...)
Affinity DataIC50: 310nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339355((+/-)-3-(4-Chlorophenyl)-3-(4-hydroxybutoxy)-2-(4-...)
Affinity DataIC50: 360nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339365((+/-)-trans-3-(4-Chlorophenyl)-3-(5-hydroxycyclooc...)
Affinity DataIC50: 380nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339370((+/-)-trans-3-(4-Chlorophenyl)-3-(4-hydroxycyclohe...)
Affinity DataIC50: 390nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339353((+/-)-(Z)-3-(4-Chlorophenyl)-3-(4-hydroxybut-2-eny...)
Affinity DataIC50: 400nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339437((+/-)-3-(4-chlorophenyl)-3-((cis)-3-hydroxycyclope...)
Affinity DataIC50: 400nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339368((+/-)-3-(4-Chlorophenyl)-3-(3-hydroxy-2,2-dimethyl...)
Affinity DataIC50: 400nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339354((+/-)-3-(4-Chlorophenyl)-3-(3-hydroxypropoxy)-2-(4...)
Affinity DataIC50: 450nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339367((+/-)-cis-3-(4-Chlorophenyl)-3-(2-hydroxymethylcyc...)
Affinity DataIC50: 570nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339361((+/-)-3-(4-Bromophenyl)-3-(4-hydroxybutoxy)-2-(4-n...)
Affinity DataIC50: 570nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339363((+/-)-trans-3-(4-Chlorophenyl)-3-(4-hydroxymethylc...)
Affinity DataIC50: 580nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339366((+/-)-3-(4-Chlorophenyl)-3-(4-hydroxybut-2-ynyloxy...)
Affinity DataIC50: 660nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339436((+/-)-3-(4-Chlorophenyl)-3-(3-hydroxycyclopentoxy)...)
Affinity DataIC50: 700nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339364((+/-)-3-(4-Chlorophenyl)-3-(3-hydroxymethylbenzylo...)
Affinity DataIC50: 730nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339357((+/-)-(S)-3-(4-Chlorophenyl)-2-[1-(4-chlorophenyl)...)
Affinity DataIC50: 900nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339362((+/-)-3-(4-Chlorophenyl)-3-(4-hydroxymethylbenzylo...)
Affinity DataIC50: 980nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339375(US8618158, NU8417 | CHEMBL1688280 | (+/-)-2-(4-Bro...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339399((-)-S-3-(4-chlorophenyl)-3-((1-(hydroxymethyl)cycl...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339360((+/-)-3-(4-Bromophenyl)-3-(3-hydroxypropoxy)-2-(4-...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339351(CHEMBL1688256 | US8618158, NU8295 | (+/-)-cis-3-(4...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339440(CHEMBL1688255 | US8618158, NU8293 | (+/-)-cis-3-(4...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339376((+/-)-3-(4-Chlorophenyl)-3-(1-hydroxymethylcyclopr...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339372(CHEMBL1688277 | US8618158, NU8415 | (+/-)-4-((1-(4...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339352(US8618158, NU8297 | CHEMBL1688257 | (+/-)-cis-3-(4...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339377((+/-)-3-(4-Chlorophenyl)-3-(1-hydroxy-2-cyclopropy...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339374(US8618158, NU8416 | CHEMBL1688279 | (+/-)-2-(4-Chl...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339438((+/-)-cis-4-((1-(4-Chlorophenyl)-1-(4-hydroxycyclo...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339408(3-(4-chlorophenyl)-3-hydroxy-2-(4-nitrobenzyl)isoi...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339358((+/-)-(R)-3-(4-Chlorophenyl)-2-[1-(4-chlorophenyl)...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339373((+/-)-3-(4-Chlorophenyl)-2-(4-fluorobenzyl)-3-(1-h...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339378((+/-)-3-(4-Chlorophenyl)-3-(1-hydroxymethylcyclopr...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339435((+/-)-(cis/trans)-2-Benzyl-3-(4-chlorophenyl)-3-(3...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339407(3-(4-Bromophenyl)-3-hydroxy-2-(4-nitrobenzyl)isoin...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339359((+/-)-3-(4-Chlorophenyl)-3-(4-hydroxybutoxy)-2-[2-...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339356((+/-)-4-[1-(4-Chlorophenyl)-1-(4-hydroxybutoxy)-3-...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339415(3-(4-Chlorophenyl)-3-hydroxy-2-(4-chlorobenzyl)iso...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339414(2-(4-bromobenzyl)-3-(4-chlorophenyl)-3-hydroxyisoi...)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339439(CHEMBL1688254 | US8618158, NU8298 | (+/-)-cis-2-Be...)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339411(2-(4-(Aminomethyl)benzonitrile)-3-(4-chlorophenyl)...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339404(3-(4-Chlorophenyl)-3-hydroxy-2-[2-(4-nitrophenyl)e...)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339403(2-(4-aminophenethyl)-3-(4-chlorophenyl)-3-hydroxyi...)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339405(3-(4-chlorophenyl)-3-hydroxy-2-phenethylisoindolin...)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339379((+/-)-3-(4-Chlorophenyl)-2-((R)-1-(4-chlorophenyl)...)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339380(CHEMBL1688285 | US8618158, NU8419 | (+/-)-3-(4-Chl...)
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339409(3-(4-Fluorophenyl)-3-hydroxy-2-(4-nitrobenzyl)-2,3...)
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339424(Methyl 4-((1-(4-chlorophenyl)-1-hydroxy-3-oxoisoin...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339392(CHEMBL1688297 | US8618158, NU8429 | (+/-)-3-(4-chl...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
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