Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50041895
TargetIntegrin alpha-4/beta-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50338194((2S)-3-(4-(dimethylcarbamoyloxy)phenyl)-2-(2-(ethy...)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of integrin alpha4beta1-mediated Jurkat cell adhesion to VCAM-1 by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50338182((2S)-3-(4-(dimethylcarbamoyloxy)phenyl)-2-(5-(3-me...)
Affinity DataIC50: 5nMAssay Description:Inhibition of integrin alpha4beta1-mediated Jurkat cell adhesion to VCAM-1 by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50338192((2S)-3-(4-(dimethylcarbamoyloxy)phenyl)-2-(2-(ethy...)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of integrin alpha4beta1-mediated Jurkat cell adhesion to VCAM-1 by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50338193((2S)-2-(2-(diethylamino)-5-ortho-tolylpyrimidin-4-...)
Affinity DataIC50: 5.70nMAssay Description:Inhibition of integrin alpha4beta1-mediated Jurkat cell adhesion to VCAM-1 by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50338187((2S)-3-(4-(dimethylcarbamoyloxy)phenyl)-2-(2-(isob...)
Affinity DataIC50: 7nMAssay Description:Inhibition of integrin alpha4beta1-mediated Jurkat cell adhesion to VCAM-1 by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50338184((S)-2-(2-(cyclohexyl(methyl)amino)quinazolin-4-yla...)
Affinity DataIC50: 8nMAssay Description:Inhibition of integrin alpha4beta1-mediated Jurkat cell adhesion to VCAM-1 by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50338189((2S)-2-(2-(cyclobutyl(methyl)amino)-5-ortho-tolylp...)
Affinity DataIC50: 10nMAssay Description:Inhibition of integrin alpha4beta1-mediated Jurkat cell adhesion to VCAM-1 by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50338173((2S)-3-(4-(dimethylcarbamoyloxy)phenyl)-2-(5-(2-me...)
Affinity DataIC50: 16nMAssay Description:Inhibition of integrin alpha4beta1-mediated Jurkat cell adhesion to VCAM-1 by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50338181((S)-3-(4-(dimethylcarbamoyloxy)phenyl)-2-(5-(thiop...)
Affinity DataIC50: 16nMAssay Description:Inhibition of integrin alpha4beta1-mediated Jurkat cell adhesion to VCAM-1 by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50338174((2S)-3-(4-(dimethylcarbamoyloxy)phenyl)-2-(5-(2-fl...)
Affinity DataIC50: 18nMAssay Description:Inhibition of integrin alpha4beta1-mediated Jurkat cell adhesion to VCAM-1 by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50338188((2S)-2-(2-(cyclopropyl(methyl)amino)-5-ortho-tolyl...)
Affinity DataIC50: 20nMAssay Description:Inhibition of integrin alpha4beta1-mediated Jurkat cell adhesion to VCAM-1 by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50338185((2S)-2-(2-(cyclohexyl(methyl)amino)-5-ortho-tolylp...)
Affinity DataIC50: 20nMAssay Description:Inhibition of integrin alpha4beta1-mediated Jurkat cell adhesion to VCAM-1 by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50338171((2S)-3-(4-(dimethylcarbamoyloxy)phenyl)-2-(5-ortho...)
Affinity DataIC50: 25nMAssay Description:Inhibition of integrin alpha4beta1-mediated Jurkat cell adhesion to VCAM-1 by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50338175((S)-2-(5-(2,6-difluorophenyl)pyrimidin-4-ylamino)-...)
Affinity DataIC50: 27nMAssay Description:Inhibition of integrin alpha4beta1-mediated Jurkat cell adhesion to VCAM-1 by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50338186((2S)-2-(2-(dimethylamino)-5-ortho-tolylpyrimidin-4...)
Affinity DataIC50: 29nMAssay Description:Inhibition of integrin alpha4beta1-mediated Jurkat cell adhesion to VCAM-1 by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50338195((2S)-3-(4-(dimethylcarbamoyloxy)phenyl)-2-(2-(pipe...)
Affinity DataIC50: 32nMAssay Description:Inhibition of integrin alpha4beta1-mediated Jurkat cell adhesion to VCAM-1 by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50338190((2S)-3-(4-(dimethylcarbamoyloxy)phenyl)-2-(2-(meth...)
Affinity DataIC50: 68nMAssay Description:Inhibition of integrin alpha4beta1-mediated Jurkat cell adhesion to VCAM-1 by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50338183((S)-2-(5-(1H-pyrrol-2-yl)pyrimidin-4-ylamino)-3-(4...)
Affinity DataIC50: 75nMAssay Description:Inhibition of integrin alpha4beta1-mediated Jurkat cell adhesion to VCAM-1 by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50338176((2S)-2-(5-(2,3-dichlorophenyl)pyrimidin-4-ylamino)...)
Affinity DataIC50: 77nMAssay Description:Inhibition of integrin alpha4beta1-mediated Jurkat cell adhesion to VCAM-1 by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50338180((S)-3-(4-(dimethylcarbamoyloxy)phenyl)-2-(5-(pyrid...)
Affinity DataIC50: 85nMAssay Description:Inhibition of integrin alpha4beta1-mediated Jurkat cell adhesion to VCAM-1 by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50338172((2S)-3-(4-(dimethylcarbamoyloxy)phenyl)-2-(5-(2-(t...)
Affinity DataIC50: 90nMAssay Description:Inhibition of integrin alpha4beta1-mediated Jurkat cell adhesion to VCAM-1 by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50338177((S)-3-(4-(dimethylcarbamoyloxy)phenyl)-2-(5-mesity...)
Affinity DataIC50: 100nMAssay Description:Inhibition of integrin alpha4beta1-mediated Jurkat cell adhesion to VCAM-1 by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50338191((2S)-2-(2-((4-chlorophenyl)(methyl)amino)-5-ortho-...)
Affinity DataIC50: 107nMAssay Description:Inhibition of integrin alpha4beta1-mediated Jurkat cell adhesion to VCAM-1 by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50338179((S)-3-(4-(dimethylcarbamoyloxy)phenyl)-2-(5-(pyrid...)
Affinity DataIC50: 130nMAssay Description:Inhibition of integrin alpha4beta1-mediated Jurkat cell adhesion to VCAM-1 by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50338168((S)-2-benzamido-3-(4-(dimethylcarbamoyloxy)phenyl)...)
Affinity DataIC50: 130nMAssay Description:Inhibition of integrin alpha4beta1-mediated Jurkat cell adhesion to VCAM-1 by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50338178((S)-3-(4-(dimethylcarbamoyloxy)phenyl)-2-(5-(3-nit...)
Affinity DataIC50: 180nMAssay Description:Inhibition of integrin alpha4beta1-mediated Jurkat cell adhesion to VCAM-1 by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50338169((S)-3-(4-(dimethylcarbamoyloxy)phenyl)-2-(quinazol...)
Affinity DataIC50: 190nMAssay Description:Inhibition of integrin alpha4beta1-mediated Jurkat cell adhesion to VCAM-1 by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50338170((S)-3-(4-(dimethylcarbamoyloxy)phenyl)-2-(5-phenyl...)
Affinity DataIC50: 300nMAssay Description:Inhibition of integrin alpha4beta1-mediated Jurkat cell adhesion to VCAM-1 by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed