Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50033316
TargetProstaglandin G/H synthase 1(Sheep)
University of Veterinary and Pharmaceutical Sciences Brno

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 300nMAssay Description:Inhibition of ram seminal vesicle COX-1 assessed as PGE2 production from arachidonic acid after 20 mins enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
University of Veterinary and Pharmaceutical Sciences Brno

Curated by ChEMBL
LigandPNGBDBM50193718(cid_5319925 | CHEMBL221907 | 2-(2,4-dihydroxypheny...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of ram seminal vesicle COX-1 assessed as PGE2 production from arachidonic acid after 20 mins enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Veterinary and Pharmaceutical Sciences Brno

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human recombinant COX-2 assessed as PGE2 production from arachidonic acid after 20 mins enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Human)
University of Veterinary and Pharmaceutical Sciences Brno

Curated by ChEMBL
LigandPNGBDBM50193718(cid_5319925 | CHEMBL221907 | 2-(2,4-dihydroxypheny...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human recombinant COX-2 assessed as PGE2 production from arachidonic acid after 20 mins enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Veterinary and Pharmaceutical Sciences Brno

Curated by ChEMBL
LigandPNGBDBM50242014(Morusin, 3 | cid_5281671 | Morusin | CHEMBL464006 ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant COX-2 assessed as PGE2 production from arachidonic acid after 20 mins enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
University of Veterinary and Pharmaceutical Sciences Brno

Curated by ChEMBL
LigandPNGBDBM50242014(Morusin, 3 | cid_5281671 | Morusin | CHEMBL464006 ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of ram seminal vesicle COX-1 assessed as PGE2 production from arachidonic acid after 20 mins enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Veterinary and Pharmaceutical Sciences Brno

Curated by ChEMBL
LigandPNGBDBM50242014(Morusin, 3 | cid_5281671 | Morusin | CHEMBL464006 ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of 5-LOXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Human)
University of Veterinary and Pharmaceutical Sciences Brno

Curated by ChEMBL
LigandPNGBDBM50242014(Morusin, 3 | cid_5281671 | Morusin | CHEMBL464006 ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of 12-LOXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed