Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50033034
TargetAcyl-CoA desaturase 1(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338523(N-(1-methyl-1H-pyrazol-3-yl)-1-(3-(trifluoromethyl...)
Affinity DataIC50: 11nMAssay Description:Inhibition of rat liver SCD1 using [3H]-stearoylCoAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338522(5-methyl-N-(1-methyl-1H-pyrazol-3-yl)-1-(3-(triflu...)
Affinity DataIC50: 11.8nMAssay Description:Inhibition of rat liver SCD1 using [3H]-stearoylCoAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338524(1-(4-chloro-3-(trifluoromethyl)benzyl)-N-(1-methyl...)
Affinity DataIC50: 16nMAssay Description:Inhibition of rat liver SCD1 using [3H]-stearoylCoAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338525(N-(2-methyl-2H-1,2,3-triazol-4-yl)-1-(3-(trifluoro...)
Affinity DataIC50: 25nMAssay Description:Inhibition of rat liver SCD1 using [3H]-stearoylCoAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338521(N-(1-methyl-1H-pyrazol-3-yl)-1-(3-(trifluoromethox...)
Affinity DataIC50: 32nMAssay Description:Inhibition of rat liver SCD1 using [3H]-stearoylCoAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338532(1-(4-chloro-3-(trifluoromethyl)benzyl)-N-(1-methyl...)
Affinity DataIC50: 33nMAssay Description:Inhibition of rat liver SCD1 using [3H]-stearoylCoAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338526(1-(3-chlorobenzyl)-N-(1-methyl-1H-pyrazol-3-yl)-1H...)
Affinity DataIC50: 57nMAssay Description:Inhibition of rat liver SCD1 using [3H]-stearoylCoAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338527(1-(4-chloro-3-(trifluoromethyl)benzyl)-N-(1-methyl...)
Affinity DataIC50: 63nMAssay Description:Inhibition of rat liver SCD1 using [3H]-stearoylCoAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338531(1-(4-chloro-3-(trifluoromethyl)benzyl)-N-(1-methyl...)
Affinity DataIC50: 63nMAssay Description:Inhibition of rat liver SCD1 using [3H]-stearoylCoAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338520(1-(4-chlorobenzyl)-N-(diaminomethylene)-5-methyl-1...)
Affinity DataIC50: 68nMAssay Description:Inhibition of rat liver SCD1 assessed as formation of deuterated oleoylCoA by HTMS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338521(N-(1-methyl-1H-pyrazol-3-yl)-1-(3-(trifluoromethox...)
Affinity DataIC50: 88nMAssay Description:Inhibition of human SCD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338520(1-(4-chlorobenzyl)-N-(diaminomethylene)-5-methyl-1...)
Affinity DataIC50: 94nMAssay Description:Inhibition of rat liver SCD1 using [3H]-stearoylCoAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338528(1-((1-(cyclopropylmethyl)cyclobutyl)methyl)-N-(1-m...)
Affinity DataIC50: 101nMAssay Description:Inhibition of rat liver SCD1 using [3H]-stearoylCoAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338533(N-(1-methyl-1H-pyrazol-3-yl)-1-(3-(trifluoromethyl...)
Affinity DataIC50: 113nMAssay Description:Inhibition of rat liver SCD1 using [3H]-stearoylCoAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338529(1-(2-chlorophenethyl)-N-(1-methyl-1H-pyrazol-3-yl)...)
Affinity DataIC50: 126nMAssay Description:Inhibition of rat liver SCD1 using [3H]-stearoylCoAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338520(1-(4-chlorobenzyl)-N-(diaminomethylene)-5-methyl-1...)
Affinity DataIC50: 217nMAssay Description:Inhibition of human SCD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338534(N-(1-methyl-1H-pyrazol-3-yl)-1-(3-(trifluoromethyl...)
Affinity DataIC50: 2.14E+3nMAssay Description:Inhibition of rat liver SCD1 using [3H]-stearoylCoAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338530(N-(2-acetamidoethyl)-1-(4-fluoro-3-(trifluoromethy...)
Affinity DataIC50: 2.75E+3nMAssay Description:Inhibition of rat liver SCD1 using [3H]-stearoylCoAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
LigandPNGBDBM50338522(5-methyl-N-(1-methyl-1H-pyrazol-3-yl)-1-(3-(triflu...)
Affinity DataIC50: 2.89E+4nMAssay Description:Inhibition of human ERG by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338522(5-methyl-N-(1-methyl-1H-pyrazol-3-yl)-1-(3-(triflu...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338522(5-methyl-N-(1-methyl-1H-pyrazol-3-yl)-1-(3-(triflu...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338522(5-methyl-N-(1-methyl-1H-pyrazol-3-yl)-1-(3-(triflu...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338522(5-methyl-N-(1-methyl-1H-pyrazol-3-yl)-1-(3-(triflu...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338522(5-methyl-N-(1-methyl-1H-pyrazol-3-yl)-1-(3-(triflu...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed