Compile Data Set for Download or QSAR
Report error Found 62 Enz. Inhib. hit(s) with all data for entry = 50033129
TargetSodium/glucose cotransporter 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM20880(CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium/glucose cotransporter 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50340012(6,8-dichloro-4-((5-(4-chlorophenethyl)-4-propyl-4H...)
Affinity DataIC50: 9nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50340013(6,8-dichloro-4-((5-(4-chlorophenethyl)-4-(3,3,3-tr...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50340012(6,8-dichloro-4-((5-(4-chlorophenethyl)-4-propyl-4H...)
Affinity DataIC50: 16nMAssay Description:Displacement of [3H]dapagliflozin from human SGLT2 expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50340013(6,8-dichloro-4-((5-(4-chlorophenethyl)-4-(3,3,3-tr...)
Affinity DataIC50: 19nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50340013(6,8-dichloro-4-((5-(4-chlorophenethyl)-4-(3,3,3-tr...)
Affinity DataIC50: 20nMAssay Description:Displacement of [3H]dapagliflozin from human SGLT2 expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM20880(CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...)
Affinity DataIC50: 22nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium/glucose cotransporter 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50340008(6-chloro-4-((5-(4-chlorophenethyl)-4-(cyclopropylm...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50340007(4-((4-butyl-5-(4-chlorophenethyl)-4H-1,2,4-triazol...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM20875(CHEMBL245067 | JMC511145 Compound 1 | 1-(2,4-dihyd...)
Affinity DataIC50: 36nMAssay Description:Inhibition of SGLT2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium/glucose cotransporter 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50340029(6-chloro-4-((5-(4-chlorophenethyl)-4-propyl-4H-1,2...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50340012(6,8-dichloro-4-((5-(4-chlorophenethyl)-4-propyl-4H...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50340010(6-chloro-4-((5-(4-chlorophenethyl)-4-(3,3,3-triflu...)
Affinity DataIC50: 70nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50340023(4-((5-(4-chlorobenzylthio)-4-ethyl-4H-1,2,4-triazo...)
Affinity DataIC50: 80nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50340021(6-bromo-4-((5-(4-chlorobenzylthio)-4-ethyl-4H-1,2,...)
Affinity DataIC50: 90nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50340026(8-chloro-4-((5-(4-chlorobenzylthio)-4-ethyl-4H-1,2...)
Affinity DataIC50: 150nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50340022(6-chloro-4-((5-(4-chlorobenzylthio)-4-ethyl-4H-1,2...)
Affinity DataIC50: 150nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50340009(6-chloro-4-((5-(4-chlorophenethyl)-4-isobutyl-4H-1...)
Affinity DataIC50: 160nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50340028(4-((5-(4-chlorophenethyl)-4-propyl-4H-1,2,4-triazo...)
Affinity DataIC50: 180nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50340019(4-((5-(4-chlorobenzylthio)-4-ethyl-4H-1,2,4-triazo...)
Affinity DataIC50: 250nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM20875(CHEMBL245067 | JMC511145 Compound 1 | 1-(2,4-dihyd...)
Affinity DataIC50: 330nMAssay Description:Inhibition of SGLT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM20880(CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...)
Affinity DataIC50: 370nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50340015(4-((5-(4-chlorobenzylthio)-4-ethyl-4H-1,2,4-triazo...)
Affinity DataIC50: 370nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetSodium/myo-inositol cotransporter 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM20880(CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...)
Affinity DataIC50: 380nMAssay Description:Inhibition of SGLT6 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Rat)
Amgen

Curated by ChEMBL
LigandPNGBDBM50340014(4-((5-(4-chlorobenzylthio)-4-methyl-4H-1,2,4-triaz...)
Affinity DataIC50: 400nMAssay Description:Inhibition of rat SGLT2 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50340024(7-chloro-4-((5-(4-chlorobenzylthio)-4-ethyl-4H-1,2...)
Affinity DataIC50: 430nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50340025(7-bromo-4-((5-(4-chlorobenzylthio)-4-ethyl-4H-1,2,...)
Affinity DataIC50: 520nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50340027(4-((5-(4-chlorophenethyl)-4-ethyl-4H-1,2,4-triazol...)
Affinity DataIC50: 640nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50340017(4-((5-(4-chlorobenzylthio)-4-cyclopropyl-4H-1,2,4-...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Mouse)
Amgen

Curated by ChEMBL
LigandPNGBDBM50340014(4-((5-(4-chlorobenzylthio)-4-methyl-4H-1,2,4-triaz...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of mouse SGLT2 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50340016(4-((5-(4-chlorobenzylthio)-4-isopropyl-4H-1,2,4-tr...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50340014(4-((5-(4-chlorobenzylthio)-4-methyl-4H-1,2,4-triaz...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50340011(6-chloro-4-((5-(4-chlorophenethyl)-4-cyclopropyl-4...)
Affinity DataIC50: 1.58E+3nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50340016(4-((5-(4-chlorobenzylthio)-4-isopropyl-4H-1,2,4-tr...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50340020(4-((5-(4-chlorobenzylthio)-4-ethyl-4H-1,2,4-triazo...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50340018(4-((5-(4-chlorobenzylthio)-4-phenyl-4H-1,2,4-triaz...)
Affinity DataIC50: 2.11E+3nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50340025(7-bromo-4-((5-(4-chlorobenzylthio)-4-ethyl-4H-1,2,...)
Affinity DataIC50: 2.53E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetSGLT1 protein(Mouse)
Amgen

Curated by ChEMBL
LigandPNGBDBM50340014(4-((5-(4-chlorobenzylthio)-4-methyl-4H-1,2,4-triaz...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of mouse SGLT1 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50340024(7-chloro-4-((5-(4-chlorobenzylthio)-4-ethyl-4H-1,2...)
Affinity DataIC50: 3.29E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50340018(4-((5-(4-chlorobenzylthio)-4-phenyl-4H-1,2,4-triaz...)
Affinity DataIC50: 3.47E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50340017(4-((5-(4-chlorobenzylthio)-4-cyclopropyl-4H-1,2,4-...)
Affinity DataIC50: 3.75E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50340015(4-((5-(4-chlorobenzylthio)-4-ethyl-4H-1,2,4-triazo...)
Affinity DataIC50: 4.75E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50340021(6-bromo-4-((5-(4-chlorobenzylthio)-4-ethyl-4H-1,2,...)
Affinity DataIC50: 5.32E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50340020(4-((5-(4-chlorobenzylthio)-4-ethyl-4H-1,2,4-triazo...)
Affinity DataIC50: 5.61E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50340013(6,8-dichloro-4-((5-(4-chlorophenethyl)-4-(3,3,3-tr...)
Affinity DataIC50: 6.29E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50340019(4-((5-(4-chlorobenzylthio)-4-ethyl-4H-1,2,4-triazo...)
Affinity DataIC50: 6.64E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50340009(6-chloro-4-((5-(4-chlorophenethyl)-4-isobutyl-4H-1...)
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50340014(4-((5-(4-chlorobenzylthio)-4-methyl-4H-1,2,4-triaz...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50340023(4-((5-(4-chlorobenzylthio)-4-ethyl-4H-1,2,4-triazo...)
Affinity DataIC50: 7.13E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50340008(6-chloro-4-((5-(4-chlorophenethyl)-4-(cyclopropylm...)
Affinity DataIC50: 7.28E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
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