Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50033224
TargetAdenosine receptor A3(Human)
Universita` Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50341607(1-benzyl-3-(4-oxo-3-phenyl-3,4-dihydrophthalazin-1...)
Affinity DataIC50: 1.15nMAssay Description:Antagonist activity at human cloned adenosine A3 receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP accumulation after 15 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Universita` Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50341606(1-(2,5-dimethoxyphenyl)-3-(4-oxo-3-phenyl-3,4-dihy...)
Affinity DataIC50: 8.25nMAssay Description:Antagonist activity at human cloned adenosine A3 receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP accumulation after 15 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Universita` Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50341605(4-(2-Methoxyphenyl)ureido-2-phenylphthalazin-1(2H)...)
Affinity DataIC50: 17nMAssay Description:Antagonist activity at human cloned adenosine A3 receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP accumulation after 15 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Universita` Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50341604(1-(3-methoxyphenyl)-3-(4-oxo-3-phenyl-3,4-dihydrop...)
Affinity DataIC50: 18nMAssay Description:Antagonist activity at human cloned adenosine A3 receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP accumulation after 15 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Universita` Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50341603(1-(4-methoxyphenyl)-3-(4-oxo-3-phenyl-3,4-dihydrop...)
Affinity DataIC50: 28nMAssay Description:Antagonist activity at human cloned adenosine A3 receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP accumulation after 15 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Universita` Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50341606(1-(2,5-dimethoxyphenyl)-3-(4-oxo-3-phenyl-3,4-dihy...)
Affinity DataKi:  0.776nMAssay Description:Displacement of [125I]AB-MECA from human cloned adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Universita` Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50341605(4-(2-Methoxyphenyl)ureido-2-phenylphthalazin-1(2H)...)
Affinity DataKi:  8.90nMAssay Description:Displacement of [125I]AB-MECA from human cloned adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Universita` Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50341604(1-(3-methoxyphenyl)-3-(4-oxo-3-phenyl-3,4-dihydrop...)
Affinity DataKi:  9.75nMAssay Description:Displacement of [125I]AB-MECA from human cloned adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Universita` Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50341607(1-benzyl-3-(4-oxo-3-phenyl-3,4-dihydrophthalazin-1...)
Affinity DataKi:  29.6nMAssay Description:Displacement of [125I]AB-MECA from human cloned adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetAdenosine receptor A1(Bovine)
Universita` Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50086145(1-(1-Oxo-2-phenyl-1,2-dihydro-[1,2,4]triazolo[4,3-...)
Affinity DataKi:  50.8nMAssay Description:Displacement of [3H]CHA from adenosine A1 receptor in bovine brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Universita` Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50341603(1-(4-methoxyphenyl)-3-(4-oxo-3-phenyl-3,4-dihydrop...)
Affinity DataKi:  60.6nMAssay Description:Displacement of [125I]AB-MECA from human cloned adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Universita` Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50341602(1-(4-oxo-3-phenyl-3,4-dihydrophthalazin-1-yl)-3-ph...)
Affinity DataKi:  178nMAssay Description:Displacement of [125I]AB-MECA from human cloned adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Universita` Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50341608(1-(2-methoxybenzyl)-3-(4-oxo-3-phenyl-3,4-dihydrop...)
Affinity DataKi:  274nMAssay Description:Displacement of [125I]AB-MECA from human cloned adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Universita` Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50086145(1-(1-Oxo-2-phenyl-1,2-dihydro-[1,2,4]triazolo[4,3-...)
Affinity DataKi:  276nMAssay Description:Displacement of [125I]AB-MECA from human cloned adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Universita` Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50086153(4-amino-2-phenyl-[1,2,4]triazolo[4,3-a]quinoxalin-...)
Affinity DataKi:  490nMAssay Description:Displacement of [125I]AB-MECA from human cloned adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Universita` Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50341601(N-(4-oxo-3-phenyl-3,4-dihydrophthalazin-1-yl)benza...)
Affinity DataKi:  1.10E+3nMAssay Description:Displacement of [125I]AB-MECA from human cloned adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed