Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50039392
LigandPNGBDBM50337127(US9266890, IV-1 | 2-(2-methoxy-4-(4-methylpiperazi...)
Affinity DataKd:  1.20nMAssay Description:Binding affinity to DCAMKL1 by immobilized ligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50337127(US9266890, IV-1 | 2-(2-methoxy-4-(4-methylpiperazi...)
Affinity DataKd:  10nMAssay Description:Binding affinity to DCAMKL2 by immobilized ligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetCyclin-G-associated kinase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337127(US9266890, IV-1 | 2-(2-methoxy-4-(4-methylpiperazi...)
Affinity DataKd:  450nMAssay Description:Binding affinity to GAK by immobilized ligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
LigandPNGBDBM50337127(US9266890, IV-1 | 2-(2-methoxy-4-(4-methylpiperazi...)
Affinity DataKd:  29nMAssay Description:Binding affinity to TNK1 by immobilized ligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetActivated CDC42 kinase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337127(US9266890, IV-1 | 2-(2-methoxy-4-(4-methylpiperazi...)
Affinity DataKd:  440nMAssay Description:Binding affinity to TNK2 by immobilized ligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 7(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337126(US9266890, IV-2 | CHEMBL1672987 | Scaffold, B19 | ...)
Affinity DataKd: >670nMAssay Description:Binding affinity to ERK5 by immobilized ligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 7(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337137(2-((2-methoxy-4-(4-(pyrrolidin-1-yl)piperidine-1-c...)
Affinity DataIC50: 130nMAssay Description:Inhibition of EGF-induced BMK1 autophosphorylation in human HeLa cells by SDS-PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 7(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337127(US9266890, IV-1 | 2-(2-methoxy-4-(4-methylpiperazi...)
Affinity DataIC50: 190nMAssay Description:Inhibition of EGF-induced BMK1 autophosphorylation in human HeLa cells by SDS-PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 7(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337139(11-ethyl-2-((2-methoxy-4-(4-methylpiperazin-1-yl)p...)
Affinity DataIC50: 200nMAssay Description:Inhibition of EGF-induced BMK1 autophosphorylation in human HeLa cells by SDS-PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 7(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337141(11-cyclopentyl-2-((2-methoxy-4-(4-methylpiperazin-...)
Affinity DataIC50: 200nMAssay Description:Inhibition of EGF-induced BMK1 autophosphorylation in human HeLa cells by SDS-PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 7(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337131(2-((2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperid...)
Affinity DataIC50: 200nMAssay Description:Inhibition of EGF-induced BMK1 autophosphorylation in human HeLa cells by SDS-PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 7(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337130(2-((2-methoxy-4-(piperazin-1-yl)phenyl)amino)-5,11...)
Affinity DataIC50: 230nMAssay Description:Inhibition of EGF-induced BMK1 autophosphorylation in human HeLa cells by SDS-PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 7(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337140(11-isopropyl-2-((2-methoxy-4-(4-methylpiperazin-1-...)
Affinity DataIC50: 230nMAssay Description:Inhibition of EGF-induced BMK1 autophosphorylation in human HeLa cells by SDS-PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 7(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337134(US9266890, IV-6 | Scaffold, B46 | CHEMBL1673046 | ...)
Affinity DataIC50: 240nMAssay Description:Inhibition of EGF-induced BMK1 autophosphorylation in human HeLa cells by SDS-PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMitogen-activated protein kinase 7(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337128(US9266890, IV-7 | 2-((4-(4-hydroxypiperidin-1-yl)-...)
Affinity DataIC50: 240nMAssay Description:Inhibition of EGF-induced BMK1 autophosphorylation in human HeLa cells by SDS-PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 7(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337138(4-((5,11-dimethyl-6-oxo-6,11-dihydro-5H-benzo[e]py...)
Affinity DataIC50: 240nMAssay Description:Inhibition of EGF-induced BMK1 autophosphorylation in human HeLa cells by SDS-PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 7(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337132(2-((2-methoxy-4-(1-methylpiperidin-4-yl)phenyl)ami...)
Affinity DataIC50: 260nMAssay Description:Inhibition of EGF-induced BMK1 autophosphorylation in human HeLa cells by SDS-PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 7(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337129(2-((2-methoxy-4-morpholinophenyl)amino)-5,11-dimet...)
Affinity DataIC50: 260nMAssay Description:Inhibition of EGF-induced BMK1 autophosphorylation in human HeLa cells by SDS-PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 7(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337133(5,11-dimethyl-2-((2-methyl-4-(4-methylpiperazin-1-...)
Affinity DataIC50: 280nMAssay Description:Inhibition of EGF-induced BMK1 autophosphorylation in human HeLa cells by SDS-PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 7(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337135(CHEMBL1673047 | Benzo[e]pyrimido[5,4-b][1,4]diazep...)
Affinity DataIC50: 310nMAssay Description:Inhibition of EGF-induced BMK1 autophosphorylation in human HeLa cells by SDS-PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 7(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337136(4-((5,11-dimethyl-6-oxo-6,11-dihydro-5H-benzo[e]py...)
Affinity DataIC50: 320nMAssay Description:Inhibition of EGF-induced BMK1 autophosphorylation in human HeLa cells by SDS-PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 7(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337144(8-chloro-2-((2-methoxy-4-(4-methylpiperazin-1-yl)p...)
Affinity DataIC50: 1.24E+3nMAssay Description:Inhibition of EGF-induced BMK1 autophosphorylation in human HeLa cells by SDS-PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 7(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337143(9-fluoro-2-((2-methoxy-4-(4-methylpiperazin-1-yl)p...)
Affinity DataIC50: 1.32E+3nMAssay Description:Inhibition of EGF-induced BMK1 autophosphorylation in human HeLa cells by SDS-PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 7(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337142(2-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)ami...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of EGF-induced BMK1 autophosphorylation in human HeLa cells by SDS-PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 7(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337145(9-chloro-2-((2-methoxy-4-(4-methylpiperazin-1-yl)p...)
Affinity DataIC50: 1.14E+4nMAssay Description:Inhibition of EGF-induced BMK1 autophosphorylation in human HeLa cells by SDS-PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed