Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50041910
TargetfMet-Leu-Phe receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50418335(CHEMBL1770297)
Affinity DataIC50: 158nMAssay Description:Antagonist activity at FPR1 in human neutrophils assessed as inhibition of fMLF-stimulated degranulation after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetfMet-Leu-Phe receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50418359(CHEMBL1770302)
Affinity DataIC50: 794nMAssay Description:Intrinsic activity at FPR1 in human neutrophils assessed as increase in calcium mobilization by FLIPR assay relative to fMLFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetfMet-Leu-Phe receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50418361(CHEMBL1770153)
Affinity DataIC50: 1.26E+3nMAssay Description:Intrinsic activity at FPR1 in human neutrophils assessed as increase in calcium mobilization by FLIPR assay relative to fMLFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetfMet-Leu-Phe receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50418334(CHEMBL1770298)
Affinity DataIC50: 1.58E+3nMAssay Description:Antagonist activity at human FPR1 in expressed in HEK293 cells assessed as inhibition of fMLF-stimulated intracellular calcium mobilisation after 5 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetfMet-Leu-Phe receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50418360(CHEMBL1770301)
Affinity DataIC50: 1.59E+3nMAssay Description:Intrinsic activity at FPR1 in human neutrophils assessed as increase in calcium mobilization by FLIPR assay relative to fMLFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetfMet-Leu-Phe receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50418357(CHEMBL1770304)
Affinity DataIC50: 2.51E+3nMAssay Description:Intrinsic activity at FPR1 in human neutrophils assessed as increase in calcium mobilization by FLIPR assay relative to fMLFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetfMet-Leu-Phe receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50027800(CHEMBL1770296)
Affinity DataIC50: 2.51E+3nMAssay Description:Antagonist activity at FPR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetfMet-Leu-Phe receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50418351(CHEMBL1770468)
Affinity DataIC50: 3.98E+3nMAssay Description:Intrinsic activity at FPR1 in human neutrophils assessed as increase in calcium mobilization by FLIPR assay relative to fMLFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetfMet-Leu-Phe receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50418358(CHEMBL1770303)
Affinity DataIC50: 5.01E+3nMAssay Description:Intrinsic activity at FPR1 in human neutrophils assessed as increase in calcium mobilization by FLIPR assay relative to fMLFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetfMet-Leu-Phe receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50418352(CHEMBL1770466)
Affinity DataIC50: 5.01E+3nMAssay Description:Intrinsic activity at FPR1 in human neutrophils assessed as increase in calcium mobilization by FLIPR assay relative to fMLFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetfMet-Leu-Phe receptor(Mouse)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50418334(CHEMBL1770298)
Affinity DataIC50: 2.51E+4nMAssay Description:Antagonist activity at mouse FPR1 expressed in HEK293 cells assessed as inhibition of fMLFF-stimulated intracellular calcium mobilisation by FLIPR as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed