Compile Data Set for Download or QSAR
Report error Found 45 Enz. Inhib. hit(s) with all data for entry = 50033440
TargetFibroblast growth factor receptor 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50345462(Allyl 8-Oxo-8H-acenaphtho[1,2-b]pyrrole-9-carboxyl...)
Affinity DataIC50: 19nMAssay Description:Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50345463(2-Oxo-2-(propylthio)ethyl 8-Oxo-8H-acenaphtho[1,2-...)
Affinity DataIC50: 65nMAssay Description:Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50345444(Ethyl 8-oxo-8H-acenaphtho[1,2-b]pyrrole-9-carboxyl...)
Affinity DataIC50: 74nMAssay Description:Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50345464(2-Oxo-2-(2,2,3,3,3-pentafluoropropoxy)ethyl 8-Oxo-...)
Affinity DataIC50: 77nMAssay Description:Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50345466(Allyl 3-(Allylthio)-8-oxo-8H-acenaphtho[1,2-b]pyrr...)
Affinity DataIC50: 216nMAssay Description:Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50345458(Ethyl 3-(2-Hydroxyethylthio)-8-oxo-8H-acenaphtho[1...)
Affinity DataIC50: 320nMAssay Description:Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM4882(3-(4-methyl-2-{[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-...)
Affinity DataIC50: 334nMAssay Description:Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50345470(2-Oxo-2-(2,2,3,3,3-pentafluoropropoxy)ethyl 3-(All...)
Affinity DataIC50: 424nMAssay Description:Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50345455(Ethyl 3-(Allylthio)-8-oxo-8H-acenaphtho[1,2-b]pyrr...)
Affinity DataIC50: 485nMAssay Description:Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50345468(2-Oxo-2-(propylthio)ethyl 3-(Allylthio)-8-oxo-8H-a...)
Affinity DataIC50: 577nMAssay Description:Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50345457(Ethyl 8-Oxo-3-(2-(pyrazin-2-yl)ethylthio)-8H-acena...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50345444(Ethyl 8-oxo-8H-acenaphtho[1,2-b]pyrrole-9-carboxyl...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of VEGFR1 using poly(Glu-Tyr)4:1 as substrate measured after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50345452(3-(1-(5-Methyl-1,3-oxathiolan-5-yl)ethylthio)-8-ox...)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50345445(8-oxo-8H-acenaphtho[1,2-b]pyrrole-9-carbonitrile |...)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 3(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50345444(Ethyl 8-oxo-8H-acenaphtho[1,2-b]pyrrole-9-carboxyl...)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of FGFR3 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50345467(2-Oxo-2-(propylthio)ethyl 8-Oxo-3-(propylthio)-8H-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 2(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50345444(Ethyl 8-oxo-8H-acenaphtho[1,2-b]pyrrole-9-carboxyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FGFR2 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50345465(Allyl 8-Oxo-3-(propylthio)-8H-acenaphtho[1,2-b]pyr...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 4(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50345444(Ethyl 8-oxo-8H-acenaphtho[1,2-b]pyrrole-9-carboxyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FGFR4 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50345453(8-Oxo-3-(2-(thiazolidin-3-yl)ethylthio)-8H-acenaph...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50345461(Ethyl 8-Oxo-3-(2-(thiazolidin-3-yl)ethylthio)-8H-a...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50345460(Ethyl 3-(1-(5-Methyl-1,3-oxathiolan-5-yl)ethylthio...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50345459(Ethyl 3-(2-Methyltetrahydrofuran-3-ylthio)-8-oxo-8...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50345444(Ethyl 8-oxo-8H-acenaphtho[1,2-b]pyrrole-9-carboxyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of VEGFR2 expressed in Bac-to-Bac Baculovirus expression system using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50345469(2-Oxo-2-(2,2,3,3,3-pentafluoropropoxy)ethyl 8-Oxo-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50345456(Ethyl 3-(Isopropylthio)-8-oxo-8H-acenaphtho[1,2-b]...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMacrophage-stimulating protein receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50345444(Ethyl 8-oxo-8H-acenaphtho[1,2-b]pyrrole-9-carboxyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of RON expressed in Bac-to-Bac Baculovirus expression system using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50345444(Ethyl 8-oxo-8H-acenaphtho[1,2-b]pyrrole-9-carboxyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of c-Met expressed in Bac-to-Bac Baculovirus expression system using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50345444(Ethyl 8-oxo-8H-acenaphtho[1,2-b]pyrrole-9-carboxyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDGFRbeta using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50345444(Ethyl 8-oxo-8H-acenaphtho[1,2-b]pyrrole-9-carboxyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of c-kit expressed in Bac-to-Bac Baculovirus expression system using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50345444(Ethyl 8-oxo-8H-acenaphtho[1,2-b]pyrrole-9-carboxyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of RET expressed in Bac-to-Bac Baculovirus expression system using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50345444(Ethyl 8-oxo-8H-acenaphtho[1,2-b]pyrrole-9-carboxyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGFR2 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50345444(Ethyl 8-oxo-8H-acenaphtho[1,2-b]pyrrole-9-carboxyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of c-Src expressed in Bac-to-Bac Baculovirus expression system using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50345444(Ethyl 8-oxo-8H-acenaphtho[1,2-b]pyrrole-9-carboxyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Abl using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetEphrin type-A receptor 2(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50345444(Ethyl 8-oxo-8H-acenaphtho[1,2-b]pyrrole-9-carboxyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EphA2 expressed in Bac-to-Bac Baculovirus expression system using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 2(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50345444(Ethyl 8-oxo-8H-acenaphtho[1,2-b]pyrrole-9-carboxyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EphB2 expressed in Bac-to-Bac Baculovirus expression system using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50345454(Ethyl 8-Oxo-3-(propylthio)-8H-acenaphtho[1,2-b]pyr...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50345444(Ethyl 8-oxo-8H-acenaphtho[1,2-b]pyrrole-9-carboxyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IGF1R expressed in Bac-to-Bac Baculovirus expression system using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50345446(8-Oxo-3-(propylthio)-8H-acenaphtho[1,2-b]pyrrole-9...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50345447(3-(Allylthio)-8-oxo-8H-acenaphtho[1,2-b]pyrrole-9-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50345448(3-(Isopropylthio)-8-oxo-8H-acenaphtho[1,2-b]pyrrol...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50345449(8-Oxo-3-(2-(pyrazin-2-yl)ethylthio)-8H-acenaphtho[...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50345450(3-(2-Hydroxyethylthio)-8-oxo-8H-acenaphtho[1,2-b]p...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50345451(3-(2-Methyltetrahydrofuran-3-ylthio)-8-oxo-8H-acen...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50345444(Ethyl 8-oxo-8H-acenaphtho[1,2-b]pyrrole-9-carboxyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDGFRalpha using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed