Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 50033360
Target5-hydroxytryptamine receptor 1A(Human)
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM50084855(Cyclohexanecarboxylic acid {2-[4-(2-hydroxy-phenyl...)
Affinity DataIC50: 0.770nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor expressed in HEK293 EBNA cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM86708(CHEMBL31354 | CHEMBL514874 | NSC_104911 | CAS_1467...)
Affinity DataIC50: 0.910nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor expressed in HEK293 EBNA cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM50343896(N-(2-(4-(2-Hydroxyphenyl)piperazin-1-yl)ethyl)-4-i...)
Affinity DataIC50: 1.19nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor expressed in HEK293 EBNA cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM50343894(N-(2-(4-(2-Hydroxyphenyl)piperazin-1-yl)ethyl)-4-i...)
Affinity DataIC50: 1.5nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor expressed in HEK293 EBNA cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM50343892(4-Iodo-N-(2-(4-(2-methoxyphenyl)piperazin-1-yl)eth...)
Affinity DataIC50: 2.02nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor expressed in HEK293 EBNA cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM50343890(4-Iodo-N-(2-(4-(2-methoxyphenyl)piperazin-1-yl)eth...)
Affinity DataIC50: 2.59nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor expressed in HEK293 EBNA cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM50343891(4-Iodo-N-(2-(4-(2-methoxyphenyl)piperazin-1-yl)eth...)
Affinity DataIC50: 2.61nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor expressed in HEK293 EBNA cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM50343893(N-(2-(4-(2-Hydroxyphenyl)piperazin-1-yl)ethyl)-4-i...)
Affinity DataIC50: 3.95nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor expressed in HEK293 EBNA cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM50343895(N-(2-(4-(2-Hydroxyphenyl)piperazin-1-yl)ethyl)-4-i...)
Affinity DataIC50: 4.57nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor expressed in HEK293 EBNA cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM50343889(3-Iodo-N-(2-(4-(2-methoxyphenyl)piperazin-1-yl)eth...)
Affinity DataIC50: 5.04nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor expressed in HEK293 EBNA cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM50084855(Cyclohexanecarboxylic acid {2-[4-(2-hydroxy-phenyl...)
Affinity DataKi:  0.330nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor expressed in HEK293 EBNA cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM86708(CHEMBL31354 | CHEMBL514874 | NSC_104911 | CAS_1467...)
Affinity DataKi:  0.390nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor expressed in HEK293 EBNA cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM50343896(N-(2-(4-(2-Hydroxyphenyl)piperazin-1-yl)ethyl)-4-i...)
Affinity DataKi:  0.470nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor expressed in HEK293 EBNA cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM50343894(N-(2-(4-(2-Hydroxyphenyl)piperazin-1-yl)ethyl)-4-i...)
Affinity DataKi:  0.640nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor expressed in HEK293 EBNA cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM50343892(4-Iodo-N-(2-(4-(2-methoxyphenyl)piperazin-1-yl)eth...)
Affinity DataKi:  0.870nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor expressed in HEK293 EBNA cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM50343891(4-Iodo-N-(2-(4-(2-methoxyphenyl)piperazin-1-yl)eth...)
Affinity DataKi:  1.11nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor expressed in HEK293 EBNA cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM50343890(4-Iodo-N-(2-(4-(2-methoxyphenyl)piperazin-1-yl)eth...)
Affinity DataKi:  1.11nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor expressed in HEK293 EBNA cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM50343894(N-(2-(4-(2-Hydroxyphenyl)piperazin-1-yl)ethyl)-4-i...)
Affinity DataKi:  1.40nMAssay Description:Inhibition of 5HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM50343893(N-(2-(4-(2-Hydroxyphenyl)piperazin-1-yl)ethyl)-4-i...)
Affinity DataKi:  1.68nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor expressed in HEK293 EBNA cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM50343895(N-(2-(4-(2-Hydroxyphenyl)piperazin-1-yl)ethyl)-4-i...)
Affinity DataKi:  1.95nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor expressed in HEK293 EBNA cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM50343889(3-Iodo-N-(2-(4-(2-methoxyphenyl)piperazin-1-yl)eth...)
Affinity DataKi:  2.15nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor expressed in HEK293 EBNA cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM50343890(4-Iodo-N-(2-(4-(2-methoxyphenyl)piperazin-1-yl)eth...)
Affinity DataKi:  2.20nMAssay Description:Inhibition of 5HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM86708(CHEMBL31354 | CHEMBL514874 | NSC_104911 | CAS_1467...)
Affinity DataKi:  2.20nMAssay Description:Inhibition of 5HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM86708(CHEMBL31354 | CHEMBL514874 | NSC_104911 | CAS_1467...)
Affinity DataKi:  16nMAssay Description:Inhibition of dopamine D4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM86708(CHEMBL31354 | CHEMBL514874 | NSC_104911 | CAS_1467...)
Affinity DataKi:  20nMAssay Description:Inhibition of adrenergic alpha1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM86708(CHEMBL31354 | CHEMBL514874 | NSC_104911 | CAS_1467...)
Affinity DataKi:  24nMAssay Description:Inhibition of 5HT1B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM50343894(N-(2-(4-(2-Hydroxyphenyl)piperazin-1-yl)ethyl)-4-i...)
Affinity DataKi:  25nMAssay Description:Inhibition of adrenergic Alpha-1B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM50343894(N-(2-(4-(2-Hydroxyphenyl)piperazin-1-yl)ethyl)-4-i...)
Affinity DataKi:  50nMAssay Description:Inhibition of 5HT7 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM50343890(4-Iodo-N-(2-(4-(2-methoxyphenyl)piperazin-1-yl)eth...)
Affinity DataKi:  78nMAssay Description:Inhibition of adrenergic alpha1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetAlpha-1D adrenergic receptor(Human)
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM50343890(4-Iodo-N-(2-(4-(2-methoxyphenyl)piperazin-1-yl)eth...)
Affinity DataKi:  98nMAssay Description:Inhibition of adrenergic Alpha-1D receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM50343890(4-Iodo-N-(2-(4-(2-methoxyphenyl)piperazin-1-yl)eth...)
Affinity DataKi:  121nMAssay Description:Inhibition of 5HT1B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM50343890(4-Iodo-N-(2-(4-(2-methoxyphenyl)piperazin-1-yl)eth...)
Affinity DataKi:  161nMAssay Description:Inhibition of 5HT7 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM50343894(N-(2-(4-(2-Hydroxyphenyl)piperazin-1-yl)ethyl)-4-i...)
Affinity DataKi:  176nMAssay Description:Inhibition of adrenergic alpha1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetAlpha-1D adrenergic receptor(Human)
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM50343894(N-(2-(4-(2-Hydroxyphenyl)piperazin-1-yl)ethyl)-4-i...)
Affinity DataKi:  181nMAssay Description:Inhibition of adrenergic Alpha-1D receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM50343890(4-Iodo-N-(2-(4-(2-methoxyphenyl)piperazin-1-yl)eth...)
Affinity DataKi:  185nMAssay Description:Inhibition of adrenergic Alpha-1B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM50343894(N-(2-(4-(2-Hydroxyphenyl)piperazin-1-yl)ethyl)-4-i...)
Affinity DataKi:  272nMAssay Description:Inhibition of 5HT1B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM86708(CHEMBL31354 | CHEMBL514874 | NSC_104911 | CAS_1467...)
Affinity DataKi:  322nMAssay Description:Inhibition of adrenergic Alpha-1B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM50343890(4-Iodo-N-(2-(4-(2-methoxyphenyl)piperazin-1-yl)eth...)
Affinity DataKi:  329nMAssay Description:Inhibition of dopamine D4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM50343894(N-(2-(4-(2-Hydroxyphenyl)piperazin-1-yl)ethyl)-4-i...)
Affinity DataKi:  890nMAssay Description:Inhibition of dopamine D4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM86708(CHEMBL31354 | CHEMBL514874 | NSC_104911 | CAS_1467...)
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of 5HT7 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed