Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50033397
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50344532(4-(2-(3-tert-butylphenylamino)benzo[d]thiazol-5-yl...)
Affinity DataIC50: 1nMAssay Description:Inhibition of c-Raf assessed as phosphorylation of MEK1/2 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50344525(4-(2-(3-tert-butylphenylamino)benzo[d]thiazol-5-yl...)
Affinity DataIC50: 1nMAssay Description:Inhibition of c-Raf assessed as phosphorylation of MEK1/2 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50344541(4-(2-(4-ethylphenylamino)benzo[d]oxazol-5-yloxy)-N...)
Affinity DataIC50: 1nMAssay Description:Inhibition of c-Raf assessed as phosphorylation of MEK1/2 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50344540(4-(2-(4-isopropylphenylamino)benzo[d]oxazol-5-ylox...)
Affinity DataIC50: 1nMAssay Description:Inhibition of c-Raf assessed as phosphorylation of MEK1/2 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50344548(4-(2-(3-tert-butyl phenylamino)benzo[d]oxazol-5-yl...)
Affinity DataIC50: 1nMAssay Description:Inhibition of c-Raf assessed as phosphorylation of MEK1/2 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50344530(4-(2-(4-bromophenylamino)benzo[d]thiazol-5-yloxy)-...)
Affinity DataIC50: 2nMAssay Description:Inhibition of c-Raf assessed as phosphorylation of MEK1/2 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50344538(N-methyl-4-(2-(4-(trifluoromethoxy)phenylamino)ben...)
Affinity DataIC50: 2nMAssay Description:Inhibition of c-Raf assessed as phosphorylation of MEK1/2 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50344539(4-(2-(4-butylphenylamino)benzo[d]oxazol-5-yloxy)-N...)
Affinity DataIC50: 2nMAssay Description:Inhibition of c-Raf assessed as phosphorylation of MEK1/2 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50344542(4-(2-(4-bromophenylamino)benzo[d]oxazol-5-yloxy)-N...)
Affinity DataIC50: 3nMAssay Description:Inhibition of c-Raf assessed as phosphorylation of MEK1/2 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50344527(4-(2-(4-isopropylphenylamino)benzo[d]thiazol-5-ylo...)
Affinity DataIC50: 3nMAssay Description:Inhibition of c-Raf assessed as phosphorylation of MEK1/2 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50344543(4-(2-(3-isopropylphenylamino)benzo[d]oxazol-5-ylox...)
Affinity DataIC50: 3nMAssay Description:Inhibition of c-Raf assessed as phosphorylation of MEK1/2 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50344531(4-(2-(4-chlorophenylamino)benzo[d]thiazol-5-yloxy)...)
Affinity DataIC50: 4nMAssay Description:Inhibition of c-Raf assessed as phosphorylation of MEK1/2 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50344526(N-methyl-4-(2-(4-(trifluoromethoxy)phenylamino)ben...)
Affinity DataIC50: 4nMAssay Description:Inhibition of c-Raf assessed as phosphorylation of MEK1/2 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50344534(4-(2-(3-isopropylphenylamino)benzo[d]oxazol-5-ylox...)
Affinity DataIC50: 4nMAssay Description:Inhibition of c-Raf assessed as phosphorylation of MEK1/2 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50344529(N-methyl-4-(2-(p-tolylamino)benzo[d]thiazol-5-ylox...)
Affinity DataIC50: 7nMAssay Description:Inhibition of c-Raf assessed as phosphorylation of MEK1/2 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50344528(4-(2-(4-butylphenylamino)benzo[d]thiazol-5-yloxy)-...)
Affinity DataIC50: 9nMAssay Description:Inhibition of c-Raf assessed as phosphorylation of MEK1/2 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50344536(4-(2-(4-(dimethylamino)phenylamino)benzo[d]oxazol-...)
Affinity DataIC50: 12nMAssay Description:Inhibition of c-Raf assessed as phosphorylation of MEK1/2 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM17696(4-({2-[(4-chlorophenyl)amino]-1,3-benzoxazol-5-yl}...)
Affinity DataIC50: 19nMAssay Description:Inhibition of c-Raf assessed as phosphorylation of MEK1/2 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50344544(N-methyl-4-(2-(3-(trifluoromethyl)phenylamino)benz...)
Affinity DataIC50: 27nMAssay Description:Inhibition of c-Raf assessed as phosphorylation of MEK1/2 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50344524(4-(2-(4-bromophenylamino)benzo[d]thiazol-5-yloxy)-...)
Affinity DataIC50: 41nMAssay Description:Inhibition of c-Raf assessed as phosphorylation of MEK1/2 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50344537(N-methyl-4-(2-(4-phenoxyphenylamino)benzo[d]oxazol...)
Affinity DataIC50: 53nMAssay Description:Inhibition of c-Raf assessed as phosphorylation of MEK1/2 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50344545(4-(2-(2-ethylphenylamino)benzo[d]oxazol-5-yloxy)-N...)
Affinity DataIC50: 110nMAssay Description:Inhibition of c-Raf assessed as phosphorylation of MEK1/2 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50344546(4-(2-(2-chlorophenylamino)benzo[d]oxazol-5-yloxy)-...)
Affinity DataIC50: 120nMAssay Description:Inhibition of c-Raf assessed as phosphorylation of MEK1/2 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50344533(4-(2-(3-isopropylphenylamino)benzo[d]oxazol-5-ylox...)
Affinity DataIC50: 140nMAssay Description:Inhibition of c-Raf assessed as phosphorylation of MEK1/2 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50344547(4-(2-(2-fluorophenylamino)benzo[d]oxazol-5-yloxy)-...)
Affinity DataIC50: 200nMAssay Description:Inhibition of c-Raf assessed as phosphorylation of MEK1/2 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50344535(4-(2-(4-(4-ethylpiperazin-1-yl)phenylamino)benzo[d...)
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of c-Raf assessed as phosphorylation of MEK1/2 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed