Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50033579
TargetSonic hedgehog protein(Mouse)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50249519(N-((3S,5S)-1-(benzo[d][1,3]dioxol-5-ylmethyl)-5-(p...)
Affinity DataIC50: 100nMAssay Description:Inhibition of SHH pathway in mouse Shh Light2 cells after 40 hrs by Gli-dependent luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSonic hedgehog protein(Mouse)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50232973(CHEMBL254129 | CYCLOPAMINE)
Affinity DataIC50: 300nMAssay Description:Inhibition of SHH pathway in mouse Shh Light2 cells after 40 hrs by Gli-dependent luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSonic hedgehog protein(Mouse)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50249519(N-((3S,5S)-1-(benzo[d][1,3]dioxol-5-ylmethyl)-5-(p...)
Affinity DataIC50: 300nMAssay Description:Inhibition of N-terminal SHH activated pathway in mouse C3H10T1/2 cells assessed as SAG-induced cell differentiation by alkaline phosphatase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSonic hedgehog protein(Mouse)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50232973(CHEMBL254129 | CYCLOPAMINE)
Affinity DataIC50: 600nMAssay Description:Inhibition of N-terminal SHH activated pathway in mouse C3H10T1/2 cells assessed as SAG-induced cell differentiation by alkaline phosphatase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSonic hedgehog protein(Mouse)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50347600(CHEMBL1803109)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of SHH pathway in mouse Shh Light2 cells after 40 hrs by Gli-dependent luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSonic hedgehog protein(Mouse)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50347600(CHEMBL1803109)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of N-terminal SHH activated pathway in mouse C3H10T1/2 cells assessed as SAG-induced cell differentiation by alkaline phosphatase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed