Compile Data Set for Download or QSAR
Report error Found 46 Enz. Inhib. hit(s) with all data for entry = 50033523
TargetLysine-specific histone demethylase 1A(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50346862(CHEMBL1215658)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of LSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50346534(CHEMBL1797705)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of LSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetLysine-specific demethylase 4E(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50009001(CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of JMJD2EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetLysine-specific demethylase 4E(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM81348(R115 (Reactive Blue 2) | β-Lapachone (A3) | b...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of JMJD2EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetLysine-specific demethylase 4E(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM15236(CHEMBL164 | Cannabiscetin | 3,5,7-trihydroxy-2-(3,...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of JMJD2EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetLysine-specific demethylase 4E(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM26110(N,3-dihydroxybenzamide | aromatic hydroxamic acid,...)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of JMJD2E pre-incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetLysine-specific demethylase 4E(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50306585((R)-2-(carboxyformamido)-3-(4-(4-fluorophenylsulfo...)
Affinity DataIC50: 5.00E+3nMAssay Description:Binding affinity to JMJD2EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetLysine-specific demethylase 4E(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50306581((R)-3-(4-(4-tert-butylphenylsulfonyloxy)phenyl)-2-...)
Affinity DataIC50: 5.00E+3nMAssay Description:Binding affinity to JMJD2EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetLysine-specific demethylase 4E(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50306580((R)-3-(4-(4-bromophenylsulfonyloxy)phenyl)-2-(carb...)
Affinity DataIC50: 5.40E+3nMAssay Description:Binding affinity to JMJD2EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50346867(CHEMBL1797644 | S1402)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of LSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50346865(CHEMBL1797642 | 2-PFPA)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of LSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50346866(CHEMBL1797643 | S1201)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of LSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetLysine-specific demethylase 4E(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of JMJD2E pre-incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetLysine-specific demethylase 4E(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM26110(N,3-dihydroxybenzamide | aromatic hydroxamic acid,...)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of JMJD2EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetLysine-specific demethylase 4E(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50346879(CHEMBL1797656)
Affinity DataIC50: 2.00E+5nMAssay Description:Binding affinity to JMJD2EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetLysine-specific demethylase 4E(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50346880(CHEMBL1797657)
Affinity DataIC50: 2.00E+5nMAssay Description:Binding affinity to JMJD2EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetLysine-specific demethylase 4E(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 5.40E+5nMAssay Description:Inhibition of JMJD2EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM26108((2R)-2-(formamidoformic acid)-4-phenylbutanoic aci...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human PHD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50346870(CHEMBL1797647)
Affinity DataKi:  50nMAssay Description:Inhibition of LSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50318565(CHEMBL1086217)
Affinity DataKi:  290nMAssay Description:Inhibition of GST-tagged LSD1 expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50346585(CHEMBL1795980 | S2101)
Affinity DataKi:  610nMAssay Description:Inhibition of LSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50346872(CHEMBL1797651)
Affinity DataKi:  700nMAssay Description:Inhibition of LSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50346871(CHEMBL1797650)
Affinity DataKi:  900nMAssay Description:Inhibition of LSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50346864(CHEMBL1797641 | CHEMBL3104337 | US8765820, 8)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of LSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50346863(CHEMBL1797640 | US8765820, 5b)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of LSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50346586(CHEMBL1795981 | US8765820, 5a)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of LSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50346868(CHEMBL1797645 | S2111)
Affinity DataKi:  1.50E+3nMAssay Description:Inhibition of LSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50346869(CHEMBL1797646)
Affinity DataKi:  1.80E+3nMAssay Description:Inhibition of LSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetLysine-specific demethylase 4E(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM60917(MLS001401388 | 9-chloro-5-(4-hydroxyphenyl)-2,3,4,...)
Affinity DataKi:  1.92E+3nMAssay Description:Non-competitive inhibition of JMJD2E relative to alpha-ketoglutarateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetLysine-specific demethylase 4E(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50418773(CARBIDOPA)
Affinity DataKi:  1.98E+3nMAssay Description:Uncompetitive inhibition of JMJD2E relative to alpha-ketoglutarateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50346876(CHEMBL1797653)
Affinity DataKi:  2.70E+3nMAssay Description:Reversible inhibition of LSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50346874(CHEMBL1797649)
Affinity DataKi:  2.80E+3nMAssay Description:Inhibition of GST-tagged LSD1 expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetLysine-specific demethylase 4E(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM81348(R115 (Reactive Blue 2) | β-Lapachone (A3) | b...)
Affinity DataKi:  3.55E+3nMAssay Description:Non-competitive inhibition of JMJD2E relative to alpha-ketoglutarateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetLysine-specific demethylase 4E(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50009001(CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...)
Affinity DataKi:  4.33E+3nMAssay Description:Non-competitive inhibition of JMJD2E relative to alpha-ketoglutarateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50346873(CHEMBL1797652)
Affinity DataKi:  4.40E+3nMAssay Description:Inhibition of LSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50346877(CHEMBL1797654)
Affinity DataKi:  6.11E+3nMAssay Description:Reversible inhibition of LSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM26106(CHEMBL90852 | Oxalylglycine | [(carboxymethyl)carb...)
Affinity DataKi:  8.00E+3nMAssay Description:Inhibition of human PHD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetLysine-specific histone demethylase 1A(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50346875(CHEMBL1797648)
Affinity DataKi:  8.30E+3nMAssay Description:Irreversible inhibition of LSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50318565(CHEMBL1086217)
Affinity DataKi:  8.30E+3nMAssay Description:Irreversible inhibition of LSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50318566(CHEMBL1086216)
Affinity DataKi:  1.56E+4nMAssay Description:Inhibition of recombinant GST-tagged LSD1 expressed in baculovirus transfected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50105417(CHEMBL1089 | Nardil | Phenethyl-hydrazine | PHENEL...)
Affinity DataKi:  1.76E+4nMAssay Description:Inhibition of LSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50346878(CHEMBL1797655)
Affinity DataKi:  2.42E+4nMAssay Description:Reversible inhibition of LSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha inhibitor(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM26108((2R)-2-(formamidoformic acid)-4-phenylbutanoic aci...)
Affinity DataKi:  8.30E+4nMAssay Description:Inhibition of asparaginyl hydroxylase factor-inhibiting-HIFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50240772((1R,2S)-2-phenylcyclopropanamine | cid_2723716 | (...)
Affinity DataKi:  3.57E+5nMAssay Description:Irreversible inhibition of LSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetLysine-specific demethylase 4E(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM26113(pyridine-2,4-dicarboxylic acid | cid_10365 | pyrid...)
Affinity DataKi:  9.14E+5nMAssay Description:Inhibition of JMJD2EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHypoxia-inducible factor 1-alpha inhibitor(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM26106(CHEMBL90852 | Oxalylglycine | [(carboxymethyl)carb...)
Affinity DataKi:  1.20E+6nMAssay Description:Inhibition of asparaginyl hydroxylase factor-inhibiting-HIFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)