Compile Data Set for Download or QSAR
Report error Found 243 Enz. Inhib. hit(s) with all data for entry = 50033616
TargetHistone deacetylase 6(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50348384(CHEMBL1800383)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of recombinant HDAC6 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50348373(CHEMBL1800373)
Affinity DataIC50: 1.08E+4nMAssay Description:Inhibition of recombinant HDAC6 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50348388(CHEMBL1800241)
Affinity DataIC50: 1.12E+4nMAssay Description:Inhibition of recombinant HDAC6 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 9(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50348393(CHEMBL1800246)
Affinity DataIC50: 1.17E+4nMAssay Description:Inhibition of recombinant HDAC9 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50348376(CHEMBL1800375)
Affinity DataIC50: 1.29E+4nMAssay Description:Inhibition of recombinant HDAC6 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50348397(CHEMBL1800250)
Affinity DataIC50: 1.37E+4nMAssay Description:Inhibition of recombinant HDAC6 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50348388(CHEMBL1800241)
Affinity DataIC50: 1.52E+4nMAssay Description:Inhibition of recombinant HDAC3 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50348388(CHEMBL1800241)
Affinity DataIC50: 1.64E+4nMAssay Description:Inhibition of recombinant HDAC1 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50348393(CHEMBL1800246)
Affinity DataIC50: 1.67E+4nMAssay Description:Inhibition of recombinant HDAC5 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM55151(2-[2-[3,4-bis(oxidanyl)phenyl]-2-oxidanylidene-eth...)
Affinity DataIC50: 1.67E+4nMAssay Description:Inhibition of recombinant HDAC6 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50348388(CHEMBL1800241)
Affinity DataIC50: 1.89E+4nMAssay Description:Inhibition of recombinant HDAC2 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50348388(CHEMBL1800241)
Affinity DataIC50: 2.39E+4nMAssay Description:Inhibition of recombinant HDAC8 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 7(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50348388(CHEMBL1800241)
Affinity DataIC50: 2.44E+4nMAssay Description:Inhibition of recombinant HDAC7 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50348380(CHEMBL1800379)
Affinity DataIC50: 2.48E+4nMAssay Description:Inhibition of recombinant HDAC6 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50348388(CHEMBL1800241)
Affinity DataIC50: 2.79E+4nMAssay Description:Inhibition of recombinant HDAC5 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 7(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50348393(CHEMBL1800246)
Affinity DataIC50: 3.19E+4nMAssay Description:Inhibition of recombinant HDAC7 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50348388(CHEMBL1800241)
Affinity DataIC50: 3.25E+4nMAssay Description:Inhibition of recombinant HDAC4 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50348379(CHEMBL1800378)
Affinity DataIC50: 3.26E+4nMAssay Description:Inhibition of recombinant HDAC6 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50348384(CHEMBL1800383)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of recombinant HDAC3 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50348377(CHEMBL1800376)
Affinity DataIC50: 4.01E+4nMAssay Description:Inhibition of recombinant HDAC6 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50348384(CHEMBL1800383)
Affinity DataIC50: 4.86E+4nMAssay Description:Inhibition of recombinant HDAC5 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50348393(CHEMBL1800246)
Affinity DataIC50: 5.42E+4nMAssay Description:Inhibition of recombinant HDAC4 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50348374(CHEMBL1307946)
Affinity DataIC50: 6.09E+4nMAssay Description:Inhibition of recombinant HDAC6 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50348376(CHEMBL1800375)
Affinity DataIC50: 6.70E+4nMAssay Description:Inhibition of recombinant HDAC2 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50348384(CHEMBL1800383)
Affinity DataIC50: 6.93E+4nMAssay Description:Inhibition of recombinant HDAC2 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 9(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50348388(CHEMBL1800241)
Affinity DataIC50: 7.41E+4nMAssay Description:Inhibition of recombinant HDAC9 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50348384(CHEMBL1800383)
Affinity DataIC50: 7.72E+4nMAssay Description:Inhibition of recombinant HDAC1 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50348376(CHEMBL1800375)
Affinity DataIC50: 8.23E+4nMAssay Description:Inhibition of recombinant HDAC1 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50348376(CHEMBL1800375)
Affinity DataIC50: 8.64E+4nMAssay Description:Inhibition of recombinant HDAC3 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50348393(CHEMBL1800246)
Affinity DataIC50: 8.80E+4nMAssay Description:Inhibition of recombinant HDAC6 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50348375(CHEMBL1800374)
Affinity DataIC50: 9.43E+4nMAssay Description:Inhibition of recombinant HDAC5 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50348387(CHEMBL1800385)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant HDAC5 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50348390(CHEMBL1800243)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant HDAC5 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50348391(CHEMBL1800244)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant HDAC5 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50348392(CHEMBL1800245)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant HDAC5 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50348382(CHEMBL1800381)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant HDAC5 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50348383(CHEMBL1800382)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant HDAC5 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50348385(CHEMBL1800384)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant HDAC5 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50348389(CHEMBL1800242)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant HDAC5 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50348378(CHEMBL1800377)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant HDAC5 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50348379(CHEMBL1800378)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant HDAC5 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50348380(CHEMBL1800379)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant HDAC5 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM96613(CHEMBL1722433 | 2-[(6-methyl-4-oxo-1H-pyrimidin-2-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant HDAC5 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50348381(CHEMBL1800380)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant HDAC5 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM55151(2-[2-[3,4-bis(oxidanyl)phenyl]-2-oxidanylidene-eth...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant HDAC5 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50348376(CHEMBL1800375)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant HDAC5 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50348397(CHEMBL1800250)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant HDAC5 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50348372(CHEMBL1800251)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant HDAC5 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50348373(CHEMBL1800373)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant HDAC5 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50348394(CHEMBL1800247)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant HDAC5 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
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