Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 50033900
TargetCytochrome P450 26A1(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50353578(CHEMBL1831092)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of CYP26 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50353582(CHEMBL1831083)
Affinity DataIC50: 0.350nMAssay Description:Inhibition of human CYP26A1 assessed using [11,12-3H]ATRA as substrate by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50353578(CHEMBL1831092)
Affinity DataIC50: 0.350nMAssay Description:Inhibition of human CYP26A1 assessed using [11,12-3H]ATRA as substrate by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342128(3-Imidazol-1-yl-2-methyl-3-[4-(naphthalen-2-ylamin...)
Affinity DataIC50: 3nMAssay Description:Inhibition of CYP26 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342128(3-Imidazol-1-yl-2-methyl-3-[4-(naphthalen-2-ylamin...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human CYP26A1 assessed using [11,12-3H]ATRA as substrate by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342133(Benzothiazol-2-yl-[4-((1S,2S)-2-dimethylamino-1-im...)
Affinity DataIC50: 10nMAssay Description:Inhibition of CYP26 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342133(Benzothiazol-2-yl-[4-((1S,2S)-2-dimethylamino-1-im...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human CYP26A1 assessed using [11,12-3H]ATRA as substrate by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50353574(CHEMBL1831088)
Affinity DataIC50: 12nMAssay Description:Inhibition of human CYP26A1 assessed using [11,12-3H]ATRA as substrate by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50353577(CHEMBL1831091)
Affinity DataIC50: 40nMAssay Description:Inhibition of human CYP26A1 assessed using [11,12-3H]ATRA as substrate by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50353573(CHEMBL1828655)
Affinity DataIC50: 50nMAssay Description:Inhibition of human CYP26A1 assessed using [11,12-3H]ATRA as substrate by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50353576(CHEMBL1831090)
Affinity DataIC50: 75nMAssay Description:Inhibition of human CYP26A1 assessed using [11,12-3H]ATRA as substrate by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50353575(CHEMBL1831089)
Affinity DataIC50: 120nMAssay Description:Inhibition of human CYP26A1 assessed using [11,12-3H]ATRA as substrate by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50353584(CHEMBL1831085)
Affinity DataIC50: 140nMAssay Description:Inhibition of human CYP26A1 assessed using [11,12-3H]ATRA as substrate by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50353583(CHEMBL1831084)
Affinity DataIC50: 200nMAssay Description:Inhibition of human CYP26A1 assessed using [11,12-3H]ATRA as substrate by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50353585(CHEMBL1831086)
Affinity DataIC50: 290nMAssay Description:Inhibition of human CYP26A1 assessed using [11,12-3H]ATRA as substrate by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50353581(CHEMBL1831082)
Affinity DataIC50: 300nMAssay Description:Inhibition of human CYP26A1 assessed using [11,12-3H]ATRA as substrate by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50353578(CHEMBL1831092)
Affinity DataIC50: 330nMAssay Description:Inhibition of CYP3A4 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50353580(CHEMBL1831094)
Affinity DataIC50: 350nMAssay Description:Inhibition of human CYP26A1 assessed using [11,12-3H]ATRA as substrate by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342133(Benzothiazol-2-yl-[4-((1S,2S)-2-dimethylamino-1-im...)
Affinity DataIC50: 350nMAssay Description:Inhibition of CYP3A4 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50353586(CHEMBL1831087)
Affinity DataIC50: 400nMAssay Description:Inhibition of human CYP26A1 assessed using [11,12-3H]ATRA as substrate by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50253770([4-(Imidazol-1-yl-phenyl-methyl)-phenyl]-naphthale...)
Affinity DataIC50: 500nMAssay Description:Inhibition of human CYP26A1 assessed using [11,12-3H]ATRA as substrate by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50176808(6-((3-chlorophenyl)(1H-imidazol-1-yl)methyl)-1H-be...)
Affinity DataIC50: 540nMAssay Description:Inhibition of human CYP26A1 assessed using [11,12-3H]ATRA as substrate by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342128(3-Imidazol-1-yl-2-methyl-3-[4-(naphthalen-2-ylamin...)
Affinity DataIC50: 600nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50353579(CHEMBL1831093)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human CYP26A1 assessed using [11,12-3H]ATRA as substrate by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342128(3-Imidazol-1-yl-2-methyl-3-[4-(naphthalen-2-ylamin...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of CYP1A2 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342128(3-Imidazol-1-yl-2-methyl-3-[4-(naphthalen-2-ylamin...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of CYP2C19 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50353578(CHEMBL1831092)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50353578(CHEMBL1831092)
Affinity DataIC50: 3.14E+3nMAssay Description:Inhibition of CYP2C19 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342133(Benzothiazol-2-yl-[4-((1S,2S)-2-dimethylamino-1-im...)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342133(Benzothiazol-2-yl-[4-((1S,2S)-2-dimethylamino-1-im...)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of CYP2C19 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342128(3-Imidazol-1-yl-2-methyl-3-[4-(naphthalen-2-ylamin...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of CYP2C9 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342133(Benzothiazol-2-yl-[4-((1S,2S)-2-dimethylamino-1-im...)
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of CYP1A2 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50353578(CHEMBL1831092)
Affinity DataIC50: 1.09E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342133(Benzothiazol-2-yl-[4-((1S,2S)-2-dimethylamino-1-im...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50353578(CHEMBL1831092)
Affinity DataIC50: 2.14E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed