Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50034301
TargetGlutamate carboxypeptidase 2(Human)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50304738(2-(3-((S)-1-carboxy-3-methylbutyl)ureido)pentanedi...)
Affinity DataKi:  1.08nMAssay Description:Inhibition of glutamate carboxypeptidase 2 in human LNCAP cells assessed as glutamate formation using NAAG as substrate after 60 mins by fluorometric...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate carboxypeptidase 2(Human)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50360218(CHEMBL1927827)
Affinity DataKi:  20nMAssay Description:Inhibition of glutamate carboxypeptidase 2 in human LNCAP cells assessed as glutamate formation using NAAG as substrate after 60 mins by fluorometric...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Human)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50304727((S)-2-(3-((S)-1-Carboxy-3-(methylthio)propyl)ureid...)
Affinity DataKi:  23nMAssay Description:Inhibition of glutamate carboxypeptidase 2 in human LNCAP cells assessed as glutamate formation using NAAG as substrate after 60 mins by fluorometric...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate carboxypeptidase 2(Human)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50360217(CHEMBL1927829)
Affinity DataKi:  29nMAssay Description:Inhibition of glutamate carboxypeptidase 2 in human LNCAP cells assessed as glutamate formation using NAAG as substrate after 60 mins by fluorometric...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Human)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50360219(CHEMBL1927826)
Affinity DataKi:  56nMAssay Description:Inhibition of glutamate carboxypeptidase 2 in human LNCAP cells assessed as glutamate formation using NAAG as substrate after 60 mins by fluorometric...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Human)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50360216(CHEMBL1927828)
Affinity DataKi:  72nMAssay Description:Inhibition of glutamate carboxypeptidase 2 in human LNCAP cells assessed as glutamate formation using NAAG as substrate after 60 mins by fluorometric...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Human)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50360220(CHEMBL1927825)
Affinity DataKi:  121nMAssay Description:Inhibition of glutamate carboxypeptidase 2 in human LNCAP cells assessed as glutamate formation using NAAG as substrate after 60 mins by fluorometric...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Human)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50304723((S)-2-(3-((S)-1-Carboxybutyl)ureido)-6-(4-iodobenz...)
Affinity DataKi:  145nMAssay Description:Inhibition of glutamate carboxypeptidase 2 in human LNCAP cells assessed as glutamate formation using NAAG as substrate after 60 mins by fluorometric...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Human)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50360221(CHEMBL1927824)
Affinity DataKi:  325nMAssay Description:Inhibition of glutamate carboxypeptidase 2 in human LNCAP cells assessed as glutamate formation using NAAG as substrate after 60 mins by fluorometric...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Human)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50304748((S)-2-(3-(Carboxymethyl)ureido)-6-(4-iodobenzamido...)
Affinity DataKi:  4.39E+3nMAssay Description:Inhibition of glutamate carboxypeptidase 2 in human LNCAP cells assessed as glutamate formation using NAAG as substrate after 60 mins by fluorometric...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed