Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50034043
TargetCannabinoid receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50312599(N-Cyclohexyl-4-[(2,4-dichlorophenyl)(p-tolyl)methy...)
Affinity DataKi:  0.150nMAssay Description:Displacement of [3H]-CP-55940 from human CB1 receptor expressed in CHO cells pretreated for 10 mins measured after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50355892(CHEMBL1910035)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]-CP-55940 from human CB1 receptor expressed in CHO cells pretreated for 10 mins measured after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50355892(CHEMBL1910035)
Affinity DataIC50: 0.900nMAssay Description:Antagonist activity at human CB1 receptor expressed in CHO cells coexpressing Galpha15/16 assessed as inhibition of CP55940-induced Ca2+ release afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50355891(CHEMBL1910034)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]-CP-55940 from human CB1 receptor expressed in CHO cells pretreated for 10 mins measured after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50312599(N-Cyclohexyl-4-[(2,4-dichlorophenyl)(p-tolyl)methy...)
Affinity DataIC50: 2.70nMAssay Description:Antagonist activity at human CB1 receptor expressed in CHO cells coexpressing Galpha15/16 assessed as inhibition of CP55940-induced Ca2+ release afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50355891(CHEMBL1910034)
Affinity DataIC50: 22nMAssay Description:Antagonist activity at human CB1 receptor expressed in CHO cells coexpressing Galpha15/16 assessed as inhibition of CP55940-induced Ca2+ release afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50355892(CHEMBL1910035)
Affinity DataKi:  227nMAssay Description:Displacement of [3H]-CP-55940 from human CB2 receptor expressed in CHO cells pretreated for 10 mins measured after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50355891(CHEMBL1910034)
Affinity DataKi:  242nMAssay Description:Displacement of [3H]-CP-55940 from human CB2 receptor expressed in CHO cells pretreated for 10 mins measured after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50312599(N-Cyclohexyl-4-[(2,4-dichlorophenyl)(p-tolyl)methy...)
Affinity DataKi:  329nMAssay Description:Displacement of [3H]-CP-55940 from human CB2 receptor expressed in CHO cells pretreated for 10 mins measured after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed