Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 50034111
TargetHistamine H4 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM22566(CHEMBL129198 | 5-chloro-2-[(4-methylpiperazin-1-yl...)
Affinity DataKi:  6.80nMAssay Description:Antagonist activity at human histamine H4 receptor by functional assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM22566(CHEMBL129198 | 5-chloro-2-[(4-methylpiperazin-1-yl...)
Affinity DataKi:  8nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in CHO cells after 90 mins by scintillation counting techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50357272(CHEMBL1916498)
Affinity DataKi:  23.6nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in CHO cells after 90 mins by scintillation counting techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50357277(CHEMBL1916505)
Affinity DataKi:  32.4nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in CHO cells after 90 mins by scintillation counting techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50356879(CHEMBL1915535)
Affinity DataKi:  37nMAssay Description:Antagonist activity at human histamine H4 receptor by functional assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50179335((5-chloro-1H-benzoimidazol-2-yl)(4-methylpiperazin...)
Affinity DataKi:  39.6nMAssay Description:Antagonist activity at human histamine H4 receptor by functional assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50179335((5-chloro-1H-benzoimidazol-2-yl)(4-methylpiperazin...)
Affinity DataKi:  47.7nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in CHO cells after 90 mins by scintillation counting techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50357273(CHEMBL1916499)
Affinity DataKi:  54nMAssay Description:Antagonist activity at human histamine H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50357273(CHEMBL1916499)
Affinity DataKi:  58.9nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in CHO cells after 90 mins by scintillation counting techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50356879(CHEMBL1915535)
Affinity DataKi:  82nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in CHO cells after 90 mins by scintillation counting techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50357274(CHEMBL1916500)
Affinity DataKi:  201nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in CHO cells after 90 mins by scintillation counting techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50304507(N-Benzyl-6-(4-methylpiperazin-1-yl)pyrimidin-4-ami...)
Affinity DataKi:  207nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in CHO cells after 90 mins by scintillation counting techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50356890(CHEMBL1915533)
Affinity DataKi:  212nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in CHO cells after 90 mins by scintillation counting techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50357275(CHEMBL1916501)
Affinity DataKi:  235nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in CHO cells after 90 mins by scintillation counting techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50356878(CHEMBL1915534)
Affinity DataKi:  502nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in CHO cells after 90 mins by scintillation counting techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50356878(CHEMBL1915534)
Affinity DataKi:  572nMAssay Description:Antagonist activity at human histamine H4 receptor by functional assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50357271(CHEMBL1916497)
Affinity DataKi:  593nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in CHO cells after 90 mins by scintillation counting techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50357276(CHEMBL1916502)
Affinity DataKi:  601nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in CHO cells after 90 mins by scintillation counting techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50356879(CHEMBL1915535)
Affinity DataKi:  646nMAssay Description:Antagonist activity at histamine H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50357272(CHEMBL1916498)
Affinity DataKi:  825nMAssay Description:Antagonist activity at human histamine H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50357278(CHEMBL1916503)
Affinity DataKi:  860nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in CHO cells after 90 mins by scintillation counting techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50357279(CHEMBL1916504)
Affinity DataKi:  930nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in CHO cells after 90 mins by scintillation counting techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50357268(CHEMBL1916494)
Affinity DataKi:  939nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in CHO cells after 90 mins by scintillation counting techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50060682(2-(4-Methyl-piperazin-1-yl)-quinoxaline | CHEMBL12...)
Affinity DataKi:  1.06E+3nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in CHO cells after 90 mins by scintillation counting techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50357267(CHEMBL1916493)
Affinity DataKi:  1.60E+3nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in CHO cells after 90 mins by scintillation counting techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50357266(CHEMBL1916492)
Affinity DataKi: >2.00E+3nMAssay Description:Antagonist activity at human histamine H4 receptor by functional assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50357267(CHEMBL1916493)
Affinity DataKi: >2.00E+3nMAssay Description:Antagonist activity at human histamine H4 receptor by functional assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50356889(CHEMBL1915532)
Affinity DataKi:  2.11E+3nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in CHO cells after 90 mins by scintillation counting techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50357266(CHEMBL1916492)
Affinity DataKi:  2.50E+3nMAssay Description:Antagonist activity at histamine H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50357266(CHEMBL1916492)
Affinity DataKi:  3.24E+3nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in CHO cells after 90 mins by scintillation counting techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50356879(CHEMBL1915535)
Affinity DataKi:  3.56E+3nMAssay Description:Antagonist activity at histamine H2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50356878(CHEMBL1915534)
Affinity DataKi:  8.22E+3nMAssay Description:Antagonist activity at histamine H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50356878(CHEMBL1915534)
Affinity DataKi:  8.82E+3nMAssay Description:Antagonist activity at histamine H2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50356879(CHEMBL1915535)
Affinity DataKi: >1.00E+4nMAssay Description:Antagonist activity at histamine H1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50357268(CHEMBL1916494)
Affinity DataKi:  1.36E+4nMAssay Description:Antagonist activity at histamine H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50357269(CHEMBL1916495)
Affinity DataKi:  2.00E+4nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in CHO cells after 90 mins by scintillation counting techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50357270(CHEMBL1916496)
Affinity DataKi:  2.00E+4nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in CHO cells after 90 mins by scintillation counting techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50357265(CHEMBL1916491)
Affinity DataKi:  3.49E+4nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in CHO cells after 90 mins by scintillation counting techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50356878(CHEMBL1915534)
Affinity DataKi: >4.00E+4nMAssay Description:Antagonist activity at histamine H1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed