Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50034124
TargetHeat shock protein HSP 90-beta(Human)
Sanofi-Aventis Research and Development

Curated by ChEMBL
LigandPNGBDBM50357454(CHEMBL1917878)
Affinity DataKd:  0.350nMAssay Description:Binding affinity to human Hsp90beta after overnight incubation by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Sanofi-Aventis Research and Development

Curated by ChEMBL
LigandPNGBDBM15359(17AAG | Tanespimycin | GLD-36 | (4E,6Z,8S,9S,10E,1...)
Affinity DataKd:  7.30nMAssay Description:Binding affinity to human Hsp90beta after overnight incubation by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Sanofi-Aventis Research and Development

Curated by ChEMBL
LigandPNGBDBM50357454(CHEMBL1917878)
Affinity DataIC50: 30nMAssay Description:Inhibition of HSP90beta in human SKBR3 cells assessed as down regulation of HER2 expression levels after 24 hrs by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Sanofi-Aventis Research and Development

Curated by ChEMBL
LigandPNGBDBM50357460(CHEMBL1917729)
Affinity DataIC50: 900nMAssay Description:Inhibition of HSP90beta in human SKBR3 cells assessed as down regulation of HER2 expression levels after 24 hrs by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Sanofi-Aventis Research and Development

Curated by ChEMBL
LigandPNGBDBM50357458(CHEMBL1917727)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of HSP90beta in human SKBR3 cells assessed as down regulation of HER2 expression levels after 24 hrs by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Sanofi-Aventis Research and Development

Curated by ChEMBL
LigandPNGBDBM50357459(CHEMBL1917728)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of HSP90beta in human SKBR3 cells assessed as down regulation of HER2 expression levels after 24 hrs by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Sanofi-Aventis Research and Development

Curated by ChEMBL
LigandPNGBDBM50357461(CHEMBL1917723)
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of human Hsp90beta after overnight incubation by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Sanofi-Aventis Research and Development

Curated by ChEMBL
LigandPNGBDBM50357455(CHEMBL1917724)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of HSP90beta in human SKBR3 cells assessed as down regulation of HER2 expression levels after 24 hrs by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Sanofi-Aventis Research and Development

Curated by ChEMBL
LigandPNGBDBM50357456(CHEMBL1917725)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of HSP90beta in human SKBR3 cells assessed as down regulation of HER2 expression levels after 24 hrs by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Sanofi-Aventis Research and Development

Curated by ChEMBL
LigandPNGBDBM50357457(CHEMBL1917726)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of HSP90beta in human SKBR3 cells assessed as down regulation of HER2 expression levels after 24 hrs by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed