Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50039504
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50379185(CHEMBL1232859)
Affinity DataKi:  2.40nMAssay Description:Inhibition of PTP1B expressed in Escherichia coli BL21 (DE3) cells using p-nitrophenyl phosphate as substrate after 2 to 3 mins by spectrophotometric...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50341986(6-hydroxy-3-(1-(2-(4-morpholinophenylamino)-2-oxoe...)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis PTPBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50335895(6-hydroxy-3-(1-(4-(naphthalen-1-ylamino)-4-oxobuty...)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of Lyp-mediated pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50308158(3-{1-[3-(biphenyl-4-ylamino)-3-oxopropyl]-1H-1,2,3...)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of SHP2 expressed in Escherichia coli BL21 (DE3) cells using pNPP as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetProtein-tyrosine-phosphatase(Yersinia pestis)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50379184(CHEMBL2010868)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of Yersinia pseudotuberculosis YopHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetProtein-tyrosine-phosphatase(Yersinia pestis)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50379183(CHEMBL1231350)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of Yersinia pseudotuberculosis YopHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50379182(CHEMBL289069)
Affinity DataKi:  6.10E+4nMAssay Description:Inhibition of PTP1B expressed in Escherichia coli BL21 (DE3) cells using p-nitrophenyl phosphate as substrate after 2 to 3 mins by spectrophotometric...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetProtein-tyrosine-phosphatase(Yersinia pestis)
Indiana University

Curated by ChEMBL
LigandPNGBDBM26193(salicylic acid | 2-Hydroxybenzoate, I | CHEMBL424 ...)
Affinity DataKi:  1.00E+6nMAssay Description:Inhibition of Yersinia pseudotuberculosis YopHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM26193(salicylic acid | 2-Hydroxybenzoate, I | CHEMBL424 ...)
Affinity DataKi:  1.94E+7nMAssay Description:Inhibition of PTP1B expressed in Escherichia coli BL21 (DE3) cells using p-nitrophenyl phosphate as substrate after 2 to 3 mins by spectrophotometric...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed