Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50001251
TargetGlutamate carboxypeptidase 2(Rat)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50014185(CHEMBL91685 | 2-(3-Carboxy-acryloylamino)-pentaned...)
Affinity DataIC50: 800nMAssay Description:Concentration required for 50%inhibition of Ac-Asp-[3,4-3H]-Glu-OH hydrolysis against rat forebrain N-acetylated-alpha-linked acidic dipeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Rat)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50014188(CHEMBL93737 | 2-(3-Carboxy-2-methoxycarbonylamino-...)
Affinity DataIC50: 2.20E+3nMAssay Description:Concentration required for 50%inhibition of Ac-Asp-[3,4-3H]-Glu-OH hydrolysis against rat forebrain N-acetylated-alpha-linked acidic dipeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Rat)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50014184(CHEMBL312312 | 2-(2-Carboxy-acetylamino)-pentanedi...)
Affinity DataIC50: 2.50E+3nMAssay Description:Tested for Ac-Asp-[3,4-3H]-Glu-OH hydrolysis inhibitory activity against rat forebrain N-acetylated-alpha-linked acidic dipeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Rat)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50014187(CHEMBL90366 | 2-(3-Acetylamino-4-carboxy-butyrylam...)
Affinity DataIC50: 8.00E+3nMAssay Description:Tested for Ac-Asp-[3,4-3H]-Glu-OH hydrolysis inhibitory activity against rat forebrain N-acetylated-alpha-linked acidic dipeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Rat)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50014182(CHEMBL91492 | 2-(2-Acetylamino-4-carboxy-butyrylam...)
Affinity DataIC50: 9.00E+3nMAssay Description:Concentration required for 50%inhibition of Ac-Asp-[3,4-3H]-Glu-OH hydrolysis against rat forebrain N-Acetylated alpha-linked Dipeptidase (NAALA Dipe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Rat)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50014180(CHEMBL94282 | 2-(2-Acetylamino-3-carboxy-propionyl...)
Affinity DataIC50: 1.50E+4nMAssay Description:Concentration required for 50%inhibition of Ac-Asp-[3,4-3H]-Glu-OH hydrolysis against rat forebrain N-Acetylated alpha-linked Dipeptidase (NAALA Dipe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Rat)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50014181(CHEMBL89919 | 2-(3-Carboxy-acryloylamino)-pentaned...)
Affinity DataIC50: 8.30E+4nMAssay Description:Tested for Ac-Asp-[3,4-3H]-Glu-OH hydrolysis inhibitory activity against rat forebrain N-acetylated-alpha-linked acidic dipeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Rat)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50014189(CHEMBL90464 | 2-(2-Acetylamino-4-carboxy-butyrylam...)
Affinity DataIC50: 1.93E+5nMAssay Description:Tested for Ac-Asp-[3,4-3H]-Glu-OH hydrolysis inhibitory activity against rat forebrain N-acetylated-alpha-linked acidic dipeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Rat)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50014183(CHEMBL93976 | 3-(2-Acetylamino-3-carboxy-propionyl...)
Affinity DataIC50: 2.00E+5nMAssay Description:Tested for Ac-Asp-[3,4-3H]-Glu-OH hydrolysis inhibitory activity against rat forebrain N-acetylated-alpha-linked acidic dipeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Rat)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50014186(CHEMBL17449 | (S)-2-((S)-2-Acetylamino-3-carboxy-p...)
Affinity DataIC50: 2.50E+5nMAssay Description:Tested for Ac-Asp-[3,4-3H]-Glu-OH hydrolysis inhibitory activity against rat forebrain N-acetylated-alpha-linked acidic dipeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Rat)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50014185(CHEMBL91685 | 2-(3-Carboxy-acryloylamino)-pentaned...)
Affinity DataKi:  400nMAssay Description:Tested for Ac-Asp-[3,4-3H]-Glu-OH hydrolysis inhibitory activity against rat forebrain N-acetylated-alpha-linked acidic dipeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Rat)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50014184(CHEMBL312312 | 2-(2-Carboxy-acetylamino)-pentanedi...)
Affinity DataKi:  900nMAssay Description:Tested for Ac-Asp-[3,4-3H]-Glu-OH hydrolysis inhibitory activity against rat forebrain N-acetylated-alpha-linked acidic dipeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Rat)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50014188(CHEMBL93737 | 2-(3-Carboxy-2-methoxycarbonylamino-...)
Affinity DataKi:  1.40E+3nMAssay Description:Tested for Ac-Asp-[3,4-3H]-Glu-OH hydrolysis inhibitory activity against rat forebrain N-acetylated-alpha-linked acidic dipeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Rat)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50014187(CHEMBL90366 | 2-(3-Acetylamino-4-carboxy-butyrylam...)
Affinity DataKi:  3.20E+3nMAssay Description:Tested for Ac-Asp-[3,4-3H]-Glu-OH hydrolysis inhibitory activity against rat forebrain N-acetylated-alpha-linked acidic dipeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Rat)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50014182(CHEMBL91492 | 2-(2-Acetylamino-4-carboxy-butyrylam...)
Affinity DataKi:  3.50E+3nMAssay Description:Tested for Ac-Asp-[3,4-3H]-Glu-OH hydrolysis inhibitory activity against rat forebrain N-Acetylated alpha-linked Dipeptidase (NAALA Dipeptidase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Rat)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50014180(CHEMBL94282 | 2-(2-Acetylamino-3-carboxy-propionyl...)
Affinity DataKi:  8.50E+3nMAssay Description:Tested for Ac-Asp-[3,4-3H]-Glu-OH hydrolysis inhibitory activity against rat forebrain N-acetylated-alpha-linked acidic dipeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Rat)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50014181(CHEMBL89919 | 2-(3-Carboxy-acryloylamino)-pentaned...)
Affinity DataKi:  4.10E+4nMAssay Description:Tested for Ac-Asp-[3,4-3H]-Glu-OH hydrolysis inhibitory activity against rat forebrain N-acetylated-alpha-linked acidic dipeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed