Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 8287
TargetBeta-carbonic anhydrase 1(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universit�� Degli Studi Di Firenze

LigandPNGBDBM11627(2-N-(4-amino-3-fluoro-5-iodobenzene)-1,3,4-thiadia...)
Affinity DataKi:  120nM ΔG°:  -39.5kJ/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed
TargetBeta-carbonic anhydrase 1(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universit�� Degli Studi Di Firenze

LigandPNGBDBM11626(2-N-(4-amino-3-bromo-5-fluorobenzene)-1,3,4-thiadi...)
Affinity DataKi:  140nM ΔG°:  -39.1kJ/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed
TargetSiderophore-binding protein(Mycobacterium tuberculosis)
Universit�� Degli Studi Di Firenze

LigandPNGBDBM11622(2-N-(4-amino-3-chlorobenzene)-1,3,4-thiadiazole-2,...)
Affinity DataKi:  170nM ΔG°:  -38.6kJ/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed
TargetSiderophore-binding protein(Mycobacterium tuberculosis)
Universit�� Degli Studi Di Firenze

LigandPNGBDBM11626(2-N-(4-amino-3-bromo-5-fluorobenzene)-1,3,4-thiadi...)
Affinity DataKi:  270nM ΔG°:  -37.5kJ/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed
TargetBeta-carbonic anhydrase 1(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universit�� Degli Studi Di Firenze

LigandPNGBDBM11622(2-N-(4-amino-3-chlorobenzene)-1,3,4-thiadiazole-2,...)
Affinity DataKi:  290nM ΔG°:  -37.3kJ/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed
TargetSiderophore-binding protein(Mycobacterium tuberculosis)
Universit�� Degli Studi Di Firenze

LigandPNGBDBM11627(2-N-(4-amino-3-fluoro-5-iodobenzene)-1,3,4-thiadia...)
Affinity DataKi:  300nM ΔG°:  -37.2kJ/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed
TargetSiderophore-binding protein(Mycobacterium tuberculosis)
Universit�� Degli Studi Di Firenze

LigandPNGBDBM10886(BZA1 | CHEMBL73962 | 2-N-benzene-1,3,4-thiadiazole...)
Affinity DataKi:  340nM ΔG°:  -36.9kJ/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed
TargetBeta-carbonic anhydrase 1(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universit�� Degli Studi Di Firenze

LigandPNGBDBM11611(4-amino-3,5-dibromobenzene-1-sulfonamide | 4-Amino...)
Affinity DataKi:  410nM ΔG°:  -36.5kJ/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universit�� Degli Studi Di Firenze

LigandPNGBDBM11627(2-N-(4-amino-3-fluoro-5-iodobenzene)-1,3,4-thiadia...)
Affinity DataKi:  410nM ΔG°:  -36.5kJ/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universit�� Degli Studi Di Firenze

LigandPNGBDBM11626(2-N-(4-amino-3-bromo-5-fluorobenzene)-1,3,4-thiadi...)
Affinity DataKi:  430nM ΔG°:  -36.3kJ/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universit�� Degli Studi Di Firenze

LigandPNGBDBM11622(2-N-(4-amino-3-chlorobenzene)-1,3,4-thiadiazole-2,...)
Affinity DataKi:  450nM ΔG°:  -36.2kJ/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universit�� Degli Studi Di Firenze

LigandPNGBDBM10886(BZA1 | CHEMBL73962 | 2-N-benzene-1,3,4-thiadiazole...)
Affinity DataKi:  460nM ΔG°:  -36.2kJ/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed
TargetBeta-carbonic anhydrase 1(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universit�� Degli Studi Di Firenze

LigandPNGBDBM11609(4-amino-3-bromo-5-chlorobenzene-1-sulfonamide | 4-...)
Affinity DataKi:  580nM ΔG°:  -35.6kJ/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed
TargetBeta-carbonic anhydrase 1(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universit�� Degli Studi Di Firenze

LigandPNGBDBM10886(BZA1 | CHEMBL73962 | 2-N-benzene-1,3,4-thiadiazole...)
Affinity DataKi:  810nM ΔG°:  -34.8kJ/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed
TargetBeta-carbonic anhydrase 1(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universit�� Degli Studi Di Firenze

LigandPNGBDBM11606(4-Amino-5-bromo-3-fluorobenzenesulfonamide | 4-ami...)
Affinity DataKi:  940nM ΔG°:  -34.4kJ/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed
TargetBeta-carbonic anhydrase 1(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universit�� Degli Studi Di Firenze

LigandPNGBDBM11605(4-amino-3-chloro-5-fluorobenzene-1-sulfonamide | 4...)
Affinity DataKi:  1.17E+3nM ΔG°:  -33.9kJ/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed
TargetBeta-carbonic anhydrase 1(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universit�� Degli Studi Di Firenze

LigandPNGBDBM11607(4-amino-3-fluoro-5-iodobenzene-1-sulfonamide | 4-A...)
Affinity DataKi:  1.22E+3nM ΔG°:  -33.8kJ/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed
TargetBeta-carbonic anhydrase 1(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universit�� Degli Studi Di Firenze

LigandPNGBDBM11608(4-Amino-3,5-dichlorobenzenesulfonamide | 4-amino-3...)
Affinity DataKi:  1.26E+3nM ΔG°:  -33.7kJ/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed
TargetBeta-carbonic anhydrase 1(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universit�� Degli Studi Di Firenze

LigandPNGBDBM11610(4-amino-3-chloro-5-iodobenzene-1-sulfonamide | 4-A...)
Affinity DataKi:  1.27E+3nM ΔG°:  -33.7kJ/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed
TargetSiderophore-binding protein(Mycobacterium tuberculosis)
Universit�� Degli Studi Di Firenze

LigandPNGBDBM11611(4-amino-3,5-dibromobenzene-1-sulfonamide | 4-Amino...)
Affinity DataKi:  2.03E+3nM ΔG°:  -32.5kJ/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed
TargetSiderophore-binding protein(Mycobacterium tuberculosis)
Universit�� Degli Studi Di Firenze

LigandPNGBDBM11608(4-Amino-3,5-dichlorobenzenesulfonamide | 4-amino-3...)
Affinity DataKi:  2.66E+3nM ΔG°:  -31.8kJ/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed
TargetSiderophore-binding protein(Mycobacterium tuberculosis)
Universit�� Degli Studi Di Firenze

LigandPNGBDBM11610(4-amino-3-chloro-5-iodobenzene-1-sulfonamide | 4-A...)
Affinity DataKi:  2.67E+3nM ΔG°:  -31.8kJ/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed
TargetSiderophore-binding protein(Mycobacterium tuberculosis)
Universit�� Degli Studi Di Firenze

LigandPNGBDBM11609(4-amino-3-bromo-5-chlorobenzene-1-sulfonamide | 4-...)
Affinity DataKi:  2.69E+3nM ΔG°:  -31.8kJ/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed
TargetSiderophore-binding protein(Mycobacterium tuberculosis)
Universit�� Degli Studi Di Firenze

LigandPNGBDBM11607(4-amino-3-fluoro-5-iodobenzene-1-sulfonamide | 4-A...)
Affinity DataKi:  2.79E+3nM ΔG°:  -31.7kJ/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed
TargetSiderophore-binding protein(Mycobacterium tuberculosis)
Universit�� Degli Studi Di Firenze

LigandPNGBDBM11605(4-amino-3-chloro-5-fluorobenzene-1-sulfonamide | 4...)
Affinity DataKi:  3.02E+3nM ΔG°:  -31.5kJ/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed
TargetSiderophore-binding protein(Mycobacterium tuberculosis)
Universit�� Degli Studi Di Firenze

LigandPNGBDBM11606(4-Amino-5-bromo-3-fluorobenzenesulfonamide | 4-ami...)
Affinity DataKi:  3.19E+3nM ΔG°:  -31.4kJ/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universit�� Degli Studi Di Firenze

LigandPNGBDBM11608(4-Amino-3,5-dichlorobenzenesulfonamide | 4-amino-3...)
Affinity DataKi:  4.14E+3nM ΔG°:  -30.7kJ/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universit�� Degli Studi Di Firenze

LigandPNGBDBM11606(4-Amino-5-bromo-3-fluorobenzenesulfonamide | 4-ami...)
Affinity DataKi:  4.31E+3nM ΔG°:  -30.6kJ/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universit�� Degli Studi Di Firenze

LigandPNGBDBM11607(4-amino-3-fluoro-5-iodobenzene-1-sulfonamide | 4-A...)
Affinity DataKi:  4.49E+3nM ΔG°:  -30.5kJ/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universit�� Degli Studi Di Firenze

LigandPNGBDBM11611(4-amino-3,5-dibromobenzene-1-sulfonamide | 4-Amino...)
Affinity DataKi:  4.52E+3nM ΔG°:  -30.5kJ/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universit�� Degli Studi Di Firenze

LigandPNGBDBM11605(4-amino-3-chloro-5-fluorobenzene-1-sulfonamide | 4...)
Affinity DataKi:  4.56E+3nM ΔG°:  -30.5kJ/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universit�� Degli Studi Di Firenze

LigandPNGBDBM11609(4-amino-3-bromo-5-chlorobenzene-1-sulfonamide | 4-...)
Affinity DataKi:  4.62E+3nM ΔG°:  -30.5kJ/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universit�� Degli Studi Di Firenze

LigandPNGBDBM11610(4-amino-3-chloro-5-iodobenzene-1-sulfonamide | 4-A...)
Affinity DataKi:  4.74E+3nM ΔG°:  -30.4kJ/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed