Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50035842
TargetAromatase(Rat)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50014315((rac)-6-((4-chlorophenyl)(1H-1,2,4-triazol-1-yl)me...)
Affinity DataIC50: 3nMAssay Description:Binding affinity for Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50014306(CHEMBL317581 | 1-[2-(4-Chloro-benzyloxy)-2-(2,4-di...)
Affinity DataIC50: 30nMAssay Description:Binding affinity for Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50014305(CHEMBL99057 | 10-Difluoromethyl-4-hydroxy-13-methy...)
Affinity DataIC50: 3.30E+3nMAssay Description:Binding affinity for Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | C...)
Affinity DataIC50: 1.07E+6nMAssay Description:Inhibition of Cytochrome P450 19A1 activity 6 hr after oral administrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50014307(CHEMBL98998 | 10-Difluoromethyl-13-methyl-1,6,7,8,...)
Affinity DataKi:  1nMAssay Description:Binding affinity was measured on Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50011771(CHEMBL281433 | 13-Methyl-10-thiiranyl-1,6,7,8,9,10...)
Affinity DataKi:  1nMAssay Description:Binding affinity was measured on Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM10044((2S,15S)-15-methyl-2-[(methylsulfanyl)methyl]tetra...)
Affinity DataKi:  1nMAssay Description:Binding affinity was measured on Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50014316(CHEMBL98537 | 7-(4-Azido-phenylsulfanyl)-10,13-dim...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity was measured on Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50014316(CHEMBL98537 | 7-(4-Azido-phenylsulfanyl)-10,13-dim...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity was measured on Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM8611(CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...)
Affinity DataKi:  1.5nMAssay Description:Binding affinity was measured on Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50014299(CHEMBL421018 | 2,2,10,13-Tetramethyl-1,6,7,8,9,10,...)
Affinity DataKi:  2.30nMAssay Description:Binding affinity was measured on Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50014310(CHEMBL98685 | 13-Methyl-10-vinyl-1,6,7,8,9,10,11,1...)
Affinity DataKi:  3nMAssay Description:Binding affinity was measured on Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50014302(CHEMBL98105 | 10,13-Dimethyl-3-methylene-1,2,3,6,7...)
Affinity DataKi:  4.70nMAssay Description:Binding affinity was measured on Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50014319(CHEMBL329500 | 9-Hydroxy-2-phenyl-benzo[h]chromen-...)
Affinity DataKi:  5nMAssay Description:Binding affinity was measured on Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50011774(CHEMBL26093 | 13-Methyl-10-oxiranyl-1,6,7,8,9,10,1...)
Affinity DataKi:  7nMAssay Description:Binding affinity was measured on Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50014311(CHEMBL319108 | 10-Ethyl-13-methyl-1,6,7,8,9,10,11,...)
Affinity DataKi:  9nMAssay Description:Binding affinity was measured on Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50014309(CHEMBL319961 | 7-(4-Iodo-phenylsulfanyl)-10,13-dim...)
Affinity DataKi:  12nMAssay Description:Binding affinity was measured on Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50014323(CHEMBL283196 | alpha-naphthoflavone | 2-PHENYL-4H-...)
Affinity DataKi:  20nMAssay Description:Binding affinity was measured on Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50014320(LY-113174 | CHEMBL101324 | 8-Chloro-5-(4-chloro-ph...)
Affinity DataKi:  24nMAssay Description:Binding affinity for Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50014324(CHEMBL29669 | 5-[Bis-(4-chloro-phenyl)-methyl]-pyr...)
Affinity DataKi:  29nMAssay Description:Binding affinity for Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50332807((8R,9S,10R,13S,14S)-10,13-dimethyl-2,3,7,8,9,10,11...)
Affinity DataKi:  37nMAssay Description:Binding affinity was measured on Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50014308(CHEMBL101323 | 4-Amino-10,13-dimethyl-1,6,7,8,9,10...)
Affinity DataKi:  37nMAssay Description:Binding affinity was measured on Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50240798(CHEMBL132530 | 4-hyroxyandrostenedione | (8R,9S,10...)
Affinity DataKi:  50nMAssay Description:Binding affinity was measured on Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50014312(CHEMBL99706 | 13-Methyl-10-propenyl-1,6,7,8,9,10,1...)
Affinity DataKi:  56nMAssay Description:Binding affinity was measured on Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50011775(CHEMBL28806 | 13-Methyl-10-oxiranyl-1,6,7,8,9,10,1...)
Affinity DataKi:  75nMAssay Description:Binding affinity was measured on Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50011770(CHEMBL282580 | 13-Methyl-10-thiiranyl-1,6,7,8,9,10...)
Affinity DataKi:  75nMAssay Description:Binding affinity was measured on Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50421878(CHEMBL2311178)
Affinity DataKi:  180nMAssay Description:Binding affinity was measured on Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM91718(Androst-1,4-dien-3,17-dione, 7)
Affinity DataKi:  320nMAssay Description:Binding affinity was measured on Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50014314(9a,11a-Dimethyl-3a,4,5,9a,9b,10,11,11a-octahydro-3...)
Affinity DataKi:  390nMAssay Description:Binding affinity was measured on Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | C...)
Affinity DataKi:  600nMAssay Description:Binding affinity was measured on Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50014301(CHEMBL101947 | 10,13-Dimethyl-6,7,8,9,10,11,12,13,...)
Affinity DataKi:  1.10E+3nMAssay Description:Binding affinity was measured on Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50014322(CHEMBL101595 | 13-Methyl-10-propyl-1,6,7,8,9,10,11...)
Affinity DataKi:  3.00E+3nMAssay Description:Binding affinity was measured on Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50014318(CHEMBL101893 | Bromo-acetic acid 6-bromo-10,13-dim...)
Affinity DataKi:  2.50E+4nMAssay Description:Binding affinity was measured on Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50014304(CHEMBL100615 | 2-Bromo-N-[4-(10,13-dimethyl-3,17-d...)
Affinity DataKi:  3.30E+4nMAssay Description:Binding affinity was measured on Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50014325(CHEMBL99370 | 10a,12a-Dimethyl-3,4,4a,5,6,10a,10b,...)
Affinity DataKi:  3.50E+4nMAssay Description:Binding affinity was measured on Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM31768(Nizoral | CHEMBL295698 | Panfungol | Ketoconazole)
Affinity DataKi:  6.50E+4nMAssay Description:Binding affinity was measured on Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed