Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50034649
TargetTransient receptor potential M8 protein(Dog)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50365723(CHEMBL1955996)
Affinity DataIC50: 7.10nMAssay Description:Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetTransient receptor potential M8 protein(Dog)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50365714(CHEMBL1955986)
Affinity DataIC50: 7.10nMAssay Description:Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetTransient receptor potential M8 protein(Dog)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50365719(CHEMBL1955992)
Affinity DataIC50: 8.60nMAssay Description:Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetTransient receptor potential M8 protein(Dog)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50365724(CHEMBL1955997)
Affinity DataIC50: 8.90nMAssay Description:Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetTransient receptor potential M8 protein(Dog)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50365722(CHEMBL1955995)
Affinity DataIC50: 8.90nMAssay Description:Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetTransient receptor potential M8 protein(Dog)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50365715(CHEMBL1955987)
Affinity DataIC50: 8.90nMAssay Description:Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetTransient receptor potential M8 protein(Dog)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50365713(CHEMBL1955985)
Affinity DataIC50: 8.90nMAssay Description:Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetTransient receptor potential M8 protein(Dog)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50365710(CHEMBL1955989)
Affinity DataIC50: 11nMAssay Description:Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetTransient receptor potential M8 protein(Dog)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50365717(CHEMBL1955990)
Affinity DataIC50: 12.3nMAssay Description:Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetTransient receptor potential M8 protein(Dog)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50365716(CHEMBL1955988)
Affinity DataIC50: 14nMAssay Description:Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50365710(CHEMBL1955989)
Affinity DataIC50: 15nMAssay Description:Antagonist activity at human TRPM8 by calcium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50365710(CHEMBL1955989)
Affinity DataIC50: 20nMAssay Description:Antagonist activity at rat TRPM8 by calcium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetTransient receptor potential M8 protein(Dog)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50365712(CHEMBL1955984)
Affinity DataIC50: 21nMAssay Description:Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetTransient receptor potential M8 protein(Dog)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50365721(CHEMBL1955994)
Affinity DataIC50: 21nMAssay Description:Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetTransient receptor potential M8 protein(Dog)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50365725(CHEMBL1955998)
Affinity DataIC50: 31nMAssay Description:Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetTransient receptor potential M8 protein(Dog)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50365718(CHEMBL1955991)
Affinity DataIC50: 38nMAssay Description:Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetTransient receptor potential M8 protein(Dog)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50365711(CHEMBL1955867)
Affinity DataIC50: 110nMAssay Description:Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetTransient receptor potential M8 protein(Dog)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50365720(CHEMBL1955993)
Affinity DataIC50: 110nMAssay Description:Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50365710(CHEMBL1955989)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of recombinant CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50365710(CHEMBL1955989)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of recombinant CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50365710(CHEMBL1955989)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50365710(CHEMBL1955989)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50365710(CHEMBL1955989)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50365710(CHEMBL1955989)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50365710(CHEMBL1955989)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed