Compile Data Set for Download or QSAR
Report error Found 90 Enz. Inhib. hit(s) with all data for entry = 50040479
TargetAurora kinase A(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50394785(CHEMBL2163404)
Affinity DataIC50: 1nMAssay Description:Inhibition of Aurora kinase A autophosphorylation in human HEK293 cells after 2 hrs by phosphor antibody readout assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50394785(CHEMBL2163404)
Affinity DataKd:  1.70nMAssay Description:Binding affinity to Aurora kinase B catalytic domain by competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50394799(CHEMBL2163407)
Affinity DataKd:  1.70nMAssay Description:Binding affinity to Aurora kinase B catalytic domain by competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50394787(CHEMBL2163402)
Affinity DataKd:  1.90nMAssay Description:Binding affinity to Aurora kinase B catalytic domain by competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50394779(CHEMBL2163394)
Affinity DataKd:  1.90nMAssay Description:Binding affinity to Aurora kinase B catalytic domain by competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50394779(CHEMBL2163394)
Affinity DataIC50: 2nMAssay Description:Inhibition of Aurora kinase A autophosphorylation in human HEK293 cells after 2 hrs by phosphor antibody readout assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50394776(CHEMBL2163388)
Affinity DataKd:  2.20nMAssay Description:Binding affinity to Aurora kinase B catalytic domain by competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50394786(CHEMBL2163403)
Affinity DataKd:  2.40nMAssay Description:Binding affinity to Aurora kinase B catalytic domain by competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50394776(CHEMBL2163388)
Affinity DataKd:  2.5nMAssay Description:Inhibition of Aurora kinase A autophosphorylation in human HEK293 cells after 2 hrs by phosphor antibody readout assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50394786(CHEMBL2163403)
Affinity DataKd:  2.5nMAssay Description:Binding affinity to Aurora kinase B catalytic domain by competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50394783(CHEMBL2163390)
Affinity DataKd:  2.60nMAssay Description:Binding affinity to Aurora kinase B catalytic domain by competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50394789(CHEMBL2163400)
Affinity DataKd:  2.80nMAssay Description:Inhibition of Aurora kinase A autophosphorylation in human HEK293 cells after 2 hrs by phosphor antibody readout assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50394781(CHEMBL2163392)
Affinity DataKd:  2.90nMAssay Description:Binding affinity to Aurora kinase B catalytic domain by competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50394784(CHEMBL2163389)
Affinity DataKd:  2.90nMAssay Description:Binding affinity to Aurora kinase B catalytic domain by competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50394796(CHEMBL2163410)
Affinity DataKd:  2.90nMAssay Description:Binding affinity to Aurora kinase B catalytic domain by competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50394785(CHEMBL2163404)
Affinity DataEC50:  3nMAssay Description:Inhibition of Aurora kinase B in human HCT116 cells assessed as induction of 8N polyploidyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50394779(CHEMBL2163394)
Affinity DataIC50: 3nMAssay Description:Inhibition of Aurora kinase B-mediated histone H3 Ser10 phosphorylation in human HCT116 cells after 2 hrs by sandwich ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50394779(CHEMBL2163394)
Affinity DataEC50:  3nMAssay Description:Inhibition of Aurora kinase B in human HCT116 cells assessed as induction of 8N polyploidyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50394789(CHEMBL2163400)
Affinity DataKd:  3.10nMAssay Description:Binding affinity to Aurora kinase B catalytic domain by competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50394777(CHEMBL2163387)
Affinity DataKd:  3.10nMAssay Description:Binding affinity to Aurora kinase B catalytic domain by competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50394798(CHEMBL2163408)
Affinity DataKd:  3.10nMAssay Description:Binding affinity to Aurora kinase B catalytic domain by competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50394792(CHEMBL2163396)
Affinity DataKd:  3.20nMAssay Description:Binding affinity to Aurora kinase B catalytic domain by competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50394778(CHEMBL2163395)
Affinity DataKd:  3.30nMAssay Description:Binding affinity to Aurora kinase B catalytic domain by competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50394794(CHEMBL2163412)
Affinity DataKd:  3.60nMAssay Description:Binding affinity to Aurora kinase B catalytic domain by competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50394782(CHEMBL2163391)
Affinity DataKd:  3.70nMAssay Description:Binding affinity to Aurora kinase B catalytic domain by competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50394795(CHEMBL2163411)
Affinity DataKd:  3.70nMAssay Description:Binding affinity to Aurora kinase B catalytic domain by competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50394788(CHEMBL2163401)
Affinity DataKd:  4nMAssay Description:Inhibition of Aurora kinase A autophosphorylation in human HEK293 cells after 2 hrs by phosphor antibody readout assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50394783(CHEMBL2163390)
Affinity DataKd:  4nMAssay Description:Inhibition of Aurora kinase A autophosphorylation in human HEK293 cells after 2 hrs by phosphor antibody readout assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50394782(CHEMBL2163391)
Affinity DataKd:  4nMAssay Description:Inhibition of Aurora kinase A autophosphorylation in human HEK293 cells after 2 hrs by phosphor antibody readout assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50394778(CHEMBL2163395)
Affinity DataKd:  4.20nMAssay Description:Inhibition of Aurora kinase A autophosphorylation in human HEK293 cells after 2 hrs by phosphor antibody readout assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50394788(CHEMBL2163401)
Affinity DataKd:  4.30nMAssay Description:Binding affinity to Aurora kinase B catalytic domain by competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50394799(CHEMBL2163407)
Affinity DataKd:  4.5nMAssay Description:Inhibition of Aurora kinase A autophosphorylation in human HEK293 cells after 2 hrs by phosphor antibody readout assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50394795(CHEMBL2163411)
Affinity DataKd:  5.10nMAssay Description:Inhibition of Aurora kinase A autophosphorylation in human HEK293 cells after 2 hrs by phosphor antibody readout assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50394777(CHEMBL2163387)
Affinity DataKd:  5.60nMAssay Description:Inhibition of Aurora kinase A autophosphorylation in human HEK293 cells after 2 hrs by phosphor antibody readout assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50394793(CHEMBL2163413)
Affinity DataKd:  5.70nMAssay Description:Binding affinity to Aurora kinase B catalytic domain by competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50394785(CHEMBL2163404)
Affinity DataKd:  5.80nMAssay Description:Binding affinity to Aurora kinase A catalytic domain by competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50394785(CHEMBL2163404)
Affinity DataIC50: 6.10nMAssay Description:Inhibition of Aurora kinase B-mediated histone H3 Ser10 phosphorylation in human HCT116 cells after 2 hrs by sandwich ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50394791(CHEMBL2163397)
Affinity DataKd:  6.10nMAssay Description:Binding affinity to Aurora kinase B catalytic domain by competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50394777(CHEMBL2163387)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of Aurora kinase B-mediated histone H3 Ser10 phosphorylation in human HCT116 cells after 2 hrs by sandwich ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50394798(CHEMBL2163408)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of Aurora kinase B-mediated histone H3 Ser10 phosphorylation in human HCT116 cells after 2 hrs by sandwich ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50394786(CHEMBL2163403)
Affinity DataKd:  6.30nMAssay Description:Inhibition of Aurora kinase A autophosphorylation in human HEK293 cells after 2 hrs by phosphor antibody readout assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50394786(CHEMBL2163403)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of Aurora kinase B-mediated histone H3 Ser10 phosphorylation in human HCT116 cells after 2 hrs by sandwich ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50394781(CHEMBL2163392)
Affinity DataKd:  6.30nMAssay Description:Inhibition of Aurora kinase A autophosphorylation in human HEK293 cells after 2 hrs by phosphor antibody readout assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50394784(CHEMBL2163389)
Affinity DataKd:  6.40nMAssay Description:Inhibition of Aurora kinase A autophosphorylation in human HEK293 cells after 2 hrs by phosphor antibody readout assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50394797(CHEMBL2163409)
Affinity DataKd:  6.60nMAssay Description:Binding affinity to Aurora kinase B catalytic domain by competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50394800(CHEMBL2163406)
Affinity DataKd:  6.60nMAssay Description:Binding affinity to Aurora kinase B catalytic domain by competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50394780(CHEMBL2163393)
Affinity DataKd:  6.90nMAssay Description:Binding affinity to Aurora kinase B catalytic domain by competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50394776(CHEMBL2163388)
Affinity DataIC50: 7nMAssay Description:Inhibition of Aurora kinase B-mediated histone H3 Ser10 phosphorylation in human HCT116 cells after 2 hrs by sandwich ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50352318(CHEMBL1822658)
Affinity DataKd:  8nMAssay Description:Binding affinity to Aurora kinase B catalytic domain by competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50394786(CHEMBL2163403)
Affinity DataKd:  8.80nMAssay Description:Binding affinity to Aurora kinase A catalytic domain by competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
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