Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50035851
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50000492(ZACOPRIDE,R | 4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3...)
Affinity DataKi:  0.417nMAssay Description:pKi value for inhibition of [3H]LY-278584 binding to 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50000492(ZACOPRIDE,R | 4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3...)
Affinity DataKi:  0.420nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 3 receptor in rat cortical membranes using [3H]- 1-Methyl-1H-indazole-3-carboxylic acid (8-methyl-8-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50108392((3-ENDO)-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL 1H-I...)
Affinity DataKi:  1.30nMAssay Description:pKi value for inhibition of [3H]LY-278584 binding to 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50108392((3-ENDO)-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL 1H-I...)
Affinity DataKi:  1.30nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 3 receptor in rat cortical membranes using [3H]- 1-Methyl-1H-indazole-3-carboxylic acid (8-methyl-8-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50000483(CHEMBL519643 | 1-Methyl-1H-indazole-3-carboxylic a...)
Affinity DataKi:  1.60nMAssay Description:pKi value for inhibition of [3H]LY-278584 binding to 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50000483(CHEMBL519643 | 1-Methyl-1H-indazole-3-carboxylic a...)
Affinity DataKi:  1.60nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 3 receptor in rat cortical membranes using [3H]- 1-Methyl-1H-indazole-3-carboxylic acid (8-methyl-8-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM85330(NSC_68647 | CAS_68647 | ONDANSETRON | Ondansetron ...)
Affinity DataKi:  2.5nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 3 receptor in rat cortical membranes using [3H]-1-Methyl-1H-indazole-3-carboxylic acid (8-methyl-8-az...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM85330(NSC_68647 | CAS_68647 | ONDANSETRON | Ondansetron ...)
Affinity DataKi:  2.5nMAssay Description:pKi value for inhibition of [3H]LY-278584 binding to 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50014407(2-Piperazin-1-yl-quinoline (Quipazine) | CHEMBL187...)
Affinity DataKi:  3nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 3 receptor in rat cortical membranes using [3H]- 1-Methyl-1H-indazole-3-carboxylic acid (8-methyl-8-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50014407(2-Piperazin-1-yl-quinoline (Quipazine) | CHEMBL187...)
Affinity DataKi:  3nMAssay Description:pKi value for inhibition of [3H]LY-278584 binding to 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50014533(CHEMBL38582 | 1H-Indazole-3-carboxylic acid (8-met...)
Affinity DataKi:  4.30nMAssay Description:pKi value for inhibition of [3H]LY-278584 binding to 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50014533(CHEMBL38582 | 1H-Indazole-3-carboxylic acid (8-met...)
Affinity DataKi:  4.30nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 3 receptor in rat cortical membranes using [3H]- 1-Methyl-1H-indazole-3-carboxylic acid (8-methyl-8-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM82561(TROPANYL 3,5-DICHLOROBENZOATE | CAS_40796-97-2 | T...)
Affinity DataKi:  26nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 3 receptor in rat cortical membranes using [3H]- 1-Methyl-1H-indazole-3-carboxylic acid (8-methyl-8-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM82561(TROPANYL 3,5-DICHLOROBENZOATE | CAS_40796-97-2 | T...)
Affinity DataKi:  26nMAssay Description:pKi value for inhibition of [3H]LY-278584 binding to 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM48320(SMR000058471 | METOCLOPRAMIDE | METOCLOPRAMIDE HYD...)
Affinity DataKi:  501nMAssay Description:pKi value for inhibition of [3H]LY-278584 binding to 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM48320(SMR000058471 | METOCLOPRAMIDE | METOCLOPRAMIDE HYD...)
Affinity DataKi:  502nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 3 receptor in rat cortical membranes using [3H]- 1-Methyl-1H-indazole-3-carboxylic acid (8-methyl-8-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50000483(CHEMBL519643 | 1-Methyl-1H-indazole-3-carboxylic a...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1B receptor in rat cortical membranes using [3H]5-HT as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50000483(CHEMBL519643 | 1-Methyl-1H-indazole-3-carboxylic a...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1C receptor in rat cortical membranes using [3H]mesulergine as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50000483(CHEMBL519643 | 1-Methyl-1H-indazole-3-carboxylic a...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 2 receptor in rat cortical membranes using [3H]ketanserin as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50000483(CHEMBL519643 | 1-Methyl-1H-indazole-3-carboxylic a...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1A receptor in rat cortical membranes using [3H]8-OH-DPAT as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50000483(CHEMBL519643 | 1-Methyl-1H-indazole-3-carboxylic a...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1D receptor in rat cortical membranes using [3H]5-HT as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50452751(CHEMBL39109)
Affinity DataKi:  1.05E+3nMAssay Description:pKi value for inhibition of [3H]LY-278584 binding to 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50452751(CHEMBL39109)
Affinity DataKi:  1.05E+3nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 3 receptor in rat cortical membranes using [3H]- 1-Methyl-1H-indazole-3-carboxylic acid (8-methyl-8-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed