Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50039900
TargetTryptophan 2,3-dioxygenase(Human)
University of Namur (Fundp)

Curated by ChEMBL
LigandPNGBDBM50289137(6-Fluoro-3-((E)-2-pyridin-3-yl-vinyl)-1H-indole | ...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human purified TDO assessed as formation of kynurenine from N-formylkynurenine preincubated for 10 mins measured after 5 to 20 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
University of Namur (Fundp)

Curated by ChEMBL
LigandPNGBDBM50350275(CHEMBL1812520)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human purified TDO assessed as formation of kynurenine from N-formylkynurenine preincubated for 10 mins measured after 5 to 20 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
University of Namur (Fundp)

Curated by ChEMBL
LigandPNGBDBM50350267(CHEMBL1812512)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human purified TDO assessed as formation of kynurenine from N-formylkynurenine preincubated for 10 mins measured after 5 to 20 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
University of Namur (Fundp)

Curated by ChEMBL
LigandPNGBDBM50350281(CHEMBL1812527)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of human purified TDO assessed as initial rate of L-Trp oxidation at 100 uM of substrate concentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
University of Namur (Fundp)

Curated by ChEMBL
LigandPNGBDBM50350281(CHEMBL1812527)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human purified TDO assessed as formation of kynurenine from N-formylkynurenine preincubated for 10 mins measured after 5 to 20 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
University of Namur (Fundp)

Curated by ChEMBL
LigandPNGBDBM50289137(6-Fluoro-3-((E)-2-pyridin-3-yl-vinyl)-1H-indole | ...)
Affinity DataKi:  30nMAssay Description:Inhibition of liver TDOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
University of Namur (Fundp)

Curated by ChEMBL
LigandPNGBDBM50350281(CHEMBL1812527)
Affinity DataKi:  2.10E+4nMAssay Description:Competitive inhibition of human purified TDO by Henri-Michaelis-Menten equation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed