Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50040403
TargetMu-type opioid receptor(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50000092(Analog of 14-(Arylhydroxyamino)codeinone | 4-methy...)
Affinity DataKi:  0.140nMAssay Description:Displacement of [3H]DAMGO from mu-opioid receptor expressed in CHOK1 cells after overnight incubation by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataKi:  0.290nMAssay Description:Displacement of [3H]DAMGO from mu-opioid receptor expressed in CHOK1 cells after overnight incubation by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50000092(Analog of 14-(Arylhydroxyamino)codeinone | 4-methy...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]diprenorphine from kappa-opioid receptor expressed in CHOK1 cells after overnight incubation by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50393705(CHEMBL2158990)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]DAMGO from mu-opioid receptor expressed in CHOK1 cells after overnight incubation by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataIC50: 65nMAssay Description:Displacement of [3H]DAMGO from mu-opioid receptor expressed in CHOK1 cells after overnight incubation by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50000092(Analog of 14-(Arylhydroxyamino)codeinone | 4-methy...)
Affinity DataKi:  295nMAssay Description:Displacement of [3H]DPDPE from delta-opioid receptor expressed in CHOK1 cells after overnight incubation by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50393705(CHEMBL2158990)
Affinity DataIC50: 590nMAssay Description:Agonist activity at mu-opioid receptor in human SH-SY5Y cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by immun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50393705(CHEMBL2158990)
Affinity DataKi:  1.57E+3nMAssay Description:Displacement of [3H]diprenorphine from kappa-opioid receptor expressed in CHOK1 cells after overnight incubation by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataKi:  2.05E+3nMAssay Description:Displacement of [3H]diprenorphine from kappa-opioid receptor expressed in CHOK1 cells after overnight incubation by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataKi:  2.77E+3nMAssay Description:Displacement of [3H]DPDPE from delta-opioid receptor expressed in CHOK1 cells after overnight incubation by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50393705(CHEMBL2158990)
Affinity DataKi:  4.75E+3nMAssay Description:Displacement of [3H]DPDPE from delta-opioid receptor expressed in CHOK1 cells after overnight incubation by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed