Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50040300
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50392240(CHEMBL2153360)
Affinity DataKd:  37.8nMAssay Description:Antagonist activity at MDM2 (residues 25 to 109) assessed as inhibition of binding to immobilized p53 (residues 15 to 29) preincubated for 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50392241(CHEMBL2153361)
Affinity DataKd:  14nMAssay Description:Antagonist activity at MDM2 (residues 25 to 109) assessed as inhibition of binding to immobilized p53 (residues 15 to 29) preincubated for 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50392242(CHEMBL2153473)
Affinity DataKd:  0.450nMAssay Description:Antagonist activity at MDM2 (residues 25 to 109) assessed as inhibition of binding to immobilized p53 (residues 15 to 29) preincubated for 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50392243(CHEMBL2153474)
Affinity DataKd:  0.220nMAssay Description:Antagonist activity at MDM2 (residues 25 to 109) assessed as inhibition of binding to immobilized p53 (residues 15 to 29) preincubated for 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50392244(CHEMBL2153475)
Affinity DataKd:  53nMAssay Description:Antagonist activity at MDM2 (residues 25 to 109) assessed as inhibition of binding to immobilized p53 (residues 15 to 29) preincubated for 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed