Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50039999
LigandPNGBDBM50387569(CHEMBL2057714)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]-epibatidine from human nAChR alpha4beta2 expressed in human SH-EP1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandPNGBDBM50257941(7-(pyridin-3-yl)-1,7-diazaspiro[4.4]nonane | CHEMB...)
Affinity DataKi:  29nMAssay Description:Displacement of [3H]-epibatidine from human nAChR alpha4beta2 expressed in human SH-EP1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandPNGBDBM50387567(CHEMBL2057712)
Affinity DataKi:  29nMAssay Description:Displacement of [3H]-epibatidine from human nAChR alpha4beta2 expressed in human SH-EP1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandPNGBDBM50387568(CHEMBL2057713)
Affinity DataKi:  32nMAssay Description:Displacement of [3H]-epibatidine from human nAChR alpha4beta2 expressed in human SH-EP1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandPNGBDBM50387569(CHEMBL2057714)
Affinity DataKi:  560nMAssay Description:Binding affinity to human ganglionic nAChR alpha3beta4 expressed in human SHSY-5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandPNGBDBM50387568(CHEMBL2057713)
Affinity DataKi:  1.10E+3nMAssay Description:Binding affinity to human ganglionic nAChR alpha3beta4 expressed in human SHSY-5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandPNGBDBM50257941(7-(pyridin-3-yl)-1,7-diazaspiro[4.4]nonane | CHEMB...)
Affinity DataKi:  1.20E+3nMAssay Description:Binding affinity to human ganglionic nAChR alpha3beta4 expressed in human SHSY-5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandPNGBDBM50387567(CHEMBL2057712)
Affinity DataKi:  2.40E+3nMAssay Description:Binding affinity to human ganglionic nAChR alpha3beta4 expressed in human SHSY-5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandPNGBDBM50387569(CHEMBL2057714)
Affinity DataEC50:  2.60E+3nMAssay Description:Antagonist activity at human ganglionic nAChR alpha3beta4 expressed in human SHSY-5Y cells assessed as calcium flux by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandPNGBDBM50387568(CHEMBL2057713)
Affinity DataEC50:  6.90E+3nMAssay Description:Antagonist activity at human ganglionic nAChR alpha3beta4 expressed in human SHSY-5Y cells assessed as calcium flux by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandPNGBDBM50257941(7-(pyridin-3-yl)-1,7-diazaspiro[4.4]nonane | CHEMB...)
Affinity DataKi:  6.90E+3nMAssay Description:Binding affinity to human nAChR alpha7 expressed in HEK cells coexpressing RIC3More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandPNGBDBM50387569(CHEMBL2057714)
Affinity DataKi:  7.60E+3nMAssay Description:Binding affinity to human nAChR alpha7 expressed in HEK cells coexpressing RIC3More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandPNGBDBM50387567(CHEMBL2057712)
Affinity DataKi:  7.90E+3nMAssay Description:Binding affinity to human nAChR alpha7 expressed in HEK cells coexpressing RIC3More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandPNGBDBM50387568(CHEMBL2057713)
Affinity DataKi:  8.00E+3nMAssay Description:Binding affinity to human nAChR alpha7 expressed in HEK cells coexpressing RIC3More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandPNGBDBM50387567(CHEMBL2057712)
Affinity DataEC50:  3.10E+4nMAssay Description:Antagonist activity at human ganglionic nAChR alpha3beta4 expressed in human SHSY-5Y cells assessed as calcium flux by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandPNGBDBM50257941(7-(pyridin-3-yl)-1,7-diazaspiro[4.4]nonane | CHEMB...)
Affinity DataEC50:  5.50E+4nMAssay Description:Antagonist activity at human ganglionic nAChR alpha3beta4 expressed in human SHSY-5Y cells assessed as calcium flux by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed