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Found
20
Enz. Inhib. hit(s) with all data for entry = 50022642
Target
Receptor-type tyrosine-protein kinase FLT3
(Human)
S*BIO Pte Ltd.
Curated by
ChEMBL
Ligand
BDBM4814
(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
PC cid
PC sid
Similars
In Depth
Date in BDB:
10/13/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Receptor-type tyrosine-protein kinase FLT3
(Human)
S*BIO Pte Ltd.
Curated by
ChEMBL
Ligand
BDBM50210177
(ONX-0803 | Pacritinib | SB-1518 | SB1518)
Copy SMILES
Copy InChI
Affinity Data
IC50: 6nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Date in BDB:
10/13/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Receptor-type tyrosine-protein kinase FLT3
(Human)
S*BIO Pte Ltd.
Curated by
ChEMBL
Ligand
BDBM50210177
(ONX-0803 | Pacritinib | SB-1518 | SB1518)
Copy SMILES
Copy InChI
Affinity Data
IC50: 8nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Date in BDB:
10/13/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Receptor-type tyrosine-protein kinase FLT3
(Human)
S*BIO Pte Ltd.
Curated by
ChEMBL
Ligand
BDBM50210177
(ONX-0803 | Pacritinib | SB-1518 | SB1518)
Copy SMILES
Copy InChI
Affinity Data
IC50: 20nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Date in BDB:
10/13/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Receptor-type tyrosine-protein kinase FLT3
(Human)
S*BIO Pte Ltd.
Curated by
ChEMBL
Ligand
BDBM50210177
(ONX-0803 | Pacritinib | SB-1518 | SB1518)
Copy SMILES
Copy InChI
Affinity Data
IC50: 22nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Date in BDB:
10/13/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Tyrosine-protein kinase JAK2
(Human)
S*BIO Pte Ltd.
Curated by
ChEMBL
Ligand
BDBM50210177
(ONX-0803 | Pacritinib | SB-1518 | SB1518)
Copy SMILES
Copy InChI
Affinity Data
IC50: 23nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Date in BDB:
10/13/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Receptor-type tyrosine-protein kinase FLT3
(Human)
S*BIO Pte Ltd.
Curated by
ChEMBL
Ligand
BDBM50210177
(ONX-0803 | Pacritinib | SB-1518 | SB1518)
Copy SMILES
Copy InChI
Affinity Data
IC50: 29nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Date in BDB:
10/13/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Receptor-type tyrosine-protein kinase FLT3
(Human)
S*BIO Pte Ltd.
Curated by
ChEMBL
Ligand
BDBM50210177
(ONX-0803 | Pacritinib | SB-1518 | SB1518)
Copy SMILES
Copy InChI
Affinity Data
IC50: 33nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Date in BDB:
10/13/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Receptor-type tyrosine-protein kinase FLT3
(Human)
S*BIO Pte Ltd.
Curated by
ChEMBL
Ligand
BDBM50210177
(ONX-0803 | Pacritinib | SB-1518 | SB1518)
Copy SMILES
Copy InChI
Affinity Data
IC50: 40nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Date in BDB:
10/13/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Non-receptor tyrosine-protein kinase TYK2
(Human)
S*BIO Pte Ltd.
Curated by
ChEMBL
Ligand
BDBM50210177
(ONX-0803 | Pacritinib | SB-1518 | SB1518)
Copy SMILES
Copy InChI
Affinity Data
IC50: 50nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Date in BDB:
10/13/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Receptor-type tyrosine-protein kinase FLT3
(Human)
S*BIO Pte Ltd.
Curated by
ChEMBL
Ligand
BDBM50210177
(ONX-0803 | Pacritinib | SB-1518 | SB1518)
Copy SMILES
Copy InChI
Affinity Data
IC50: 80nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Date in BDB:
10/13/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Receptor-type tyrosine-protein kinase FLT3
(Human)
S*BIO Pte Ltd.
Curated by
ChEMBL
Ligand
BDBM50210177
(ONX-0803 | Pacritinib | SB-1518 | SB1518)
Copy SMILES
Copy InChI
Affinity Data
IC50: 180nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Date in BDB:
10/13/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Receptor-type tyrosine-protein kinase FLT3
(Human)
S*BIO Pte Ltd.
Curated by
ChEMBL
Ligand
BDBM50210177
(ONX-0803 | Pacritinib | SB-1518 | SB1518)
Copy SMILES
Copy InChI
Affinity Data
IC50: 500nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Date in BDB:
10/13/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Receptor-type tyrosine-protein kinase FLT3
(Human)
S*BIO Pte Ltd.
Curated by
ChEMBL
Ligand
BDBM50210177
(ONX-0803 | Pacritinib | SB-1518 | SB1518)
Copy SMILES
Copy InChI
Affinity Data
IC50: 500nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Date in BDB:
10/13/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Receptor-type tyrosine-protein kinase FLT3
(Human)
S*BIO Pte Ltd.
Curated by
ChEMBL
Ligand
BDBM50210177
(ONX-0803 | Pacritinib | SB-1518 | SB1518)
Copy SMILES
Copy InChI
Affinity Data
IC50: 500nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Date in BDB:
10/13/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Tyrosine-protein kinase JAK3
(Human)
S*BIO Pte Ltd.
Curated by
ChEMBL
Ligand
BDBM50210177
(ONX-0803 | Pacritinib | SB-1518 | SB1518)
Copy SMILES
Copy InChI
Affinity Data
IC50: 520nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Date in BDB:
10/13/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Receptor-type tyrosine-protein kinase FLT3
(Human)
S*BIO Pte Ltd.
Curated by
ChEMBL
Ligand
BDBM50210177
(ONX-0803 | Pacritinib | SB-1518 | SB1518)
Copy SMILES
Copy InChI
Affinity Data
IC50: 600nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Date in BDB:
10/13/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Tyrosine-protein kinase JAK1
(Human)
S*BIO Pte Ltd.
Curated by
ChEMBL
Ligand
BDBM50210177
(ONX-0803 | Pacritinib | SB-1518 | SB1518)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.28E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Date in BDB:
10/13/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Platelet-derived growth factor receptor alpha/beta
(Mouse)
S*BIO Pte Ltd.
Curated by
ChEMBL
Ligand
BDBM50355501
(RUXOLITINIB PHOSPHATE | INCB-018424 | RUXOLITINIB ...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.70E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
10/13/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Platelet-derived growth factor receptor alpha/beta
(Mouse)
S*BIO Pte Ltd.
Curated by
ChEMBL
Ligand
BDBM50355501
(RUXOLITINIB PHOSPHATE | INCB-018424 | RUXOLITINIB ...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.95E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
10/13/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL