Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50040029
TargetAcetylcholinesterase(Rat)
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50004000(CHEMBL94 | physostigmine | Antilirium | Eserine | ...)
Affinity DataIC50: 11nMAssay Description:Inhibition of AChE in Wistar rat brain homogenate using acetylthiocholine iodide as substrate after 0.5 hrs by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM10622((3aS)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyrrolo...)
Affinity DataIC50: 28.3nMAssay Description:Inhibition of AChE in Wistar rat brain homogenate using acetylthiocholine iodide as substrate after 0.5 hrs by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50004000(CHEMBL94 | physostigmine | Antilirium | Eserine | ...)
Affinity DataIC50: 58.4nMAssay Description:Inhibition of BuChE in Wistar rat plasma using acetylthiocholine iodide as substrate after 0.5 hrs by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50388138(CHEMBL2059199)
Affinity DataIC50: 373nMAssay Description:Inhibition of AChE in Wistar rat brain homogenate using acetylthiocholine iodide as substrate after 0.5 hrs by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50388133(CHEMBL2058983)
Affinity DataIC50: 397nMAssay Description:Inhibition of AChE in Wistar rat brain homogenate using acetylthiocholine iodide as substrate after 0.5 hrs by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50388137(CHEMBL2058987)
Affinity DataIC50: 644nMAssay Description:Inhibition of AChE in Wistar rat brain homogenate using acetylthiocholine iodide as substrate after 0.5 hrs by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50388131(CHEMBL2058982)
Affinity DataIC50: 749nMAssay Description:Inhibition of AChE in Wistar rat brain homogenate using acetylthiocholine iodide as substrate after 0.5 hrs by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50388135(CHEMBL2058986)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of AChE in Wistar rat brain homogenate using acetylthiocholine iodide as substrate after 0.5 hrs by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50388132(CHEMBL2058980)
Affinity DataIC50: 3.55E+3nMAssay Description:Inhibition of AChE in Wistar rat brain homogenate using acetylthiocholine iodide as substrate after 0.5 hrs by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50388130(CHEMBL2058981)
Affinity DataIC50: 3.66E+3nMAssay Description:Inhibition of AChE in Wistar rat brain homogenate using acetylthiocholine iodide as substrate after 0.5 hrs by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50388135(CHEMBL2058986)
Affinity DataIC50: 3.77E+3nMAssay Description:Inhibition of AChE in Wistar rat brain homogenate using acetylthiocholine iodide as substrate after 0.5 hrs by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50388129(CHEMBL2058979)
Affinity DataIC50: 4.36E+3nMAssay Description:Inhibition of AChE in Wistar rat brain homogenate using acetylthiocholine iodide as substrate after 0.5 hrs by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50388136(CHEMBL2058985)
Affinity DataIC50: 4.73E+3nMAssay Description:Inhibition of AChE in Wistar rat brain homogenate using acetylthiocholine iodide as substrate after 0.5 hrs by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50388139(CHEMBL2059200)
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of AChE in Wistar rat brain homogenate using acetylthiocholine iodide as substrate after 0.5 hrs by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50388128(CHEMBL2058978)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of AChE in Wistar rat brain homogenate using acetylthiocholine iodide as substrate after 0.5 hrs by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50388140(CHEMBL2058977)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of BuChE in Wistar rat plasma using acetylthiocholine iodide as substrate after 0.5 hrs by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50388128(CHEMBL2058978)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of BuChE in Wistar rat plasma using acetylthiocholine iodide as substrate after 0.5 hrs by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50388140(CHEMBL2058977)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of AChE in Wistar rat brain homogenate using acetylthiocholine iodide as substrate after 0.5 hrs by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50388134(CHEMBL2058984)
Affinity DataIC50: 1.84E+4nMAssay Description:Inhibition of AChE in Wistar rat brain homogenate using acetylthiocholine iodide as substrate after 0.5 hrs by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM10622((3aS)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyrrolo...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of BuChE in Wistar rat plasma using acetylthiocholine iodide as substrate after 0.5 hrs by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50388133(CHEMBL2058983)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of BuChE in Wistar rat plasma using acetylthiocholine iodide as substrate after 0.5 hrs by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50388131(CHEMBL2058982)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of BuChE in Wistar rat plasma using acetylthiocholine iodide as substrate after 0.5 hrs by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50388138(CHEMBL2059199)
Affinity DataIC50: 3.62E+4nMAssay Description:Inhibition of BuChE in Wistar rat plasma using acetylthiocholine iodide as substrate after 0.5 hrs by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50388137(CHEMBL2058987)
Affinity DataIC50: 4.19E+4nMAssay Description:Inhibition of BuChE in Wistar rat plasma using acetylthiocholine iodide as substrate after 0.5 hrs by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50388136(CHEMBL2058985)
Affinity DataIC50: 6.53E+4nMAssay Description:Inhibition of BuChE in Wistar rat plasma using acetylthiocholine iodide as substrate after 0.5 hrs by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50388132(CHEMBL2058980)
Affinity DataIC50: 8.73E+4nMAssay Description:Inhibition of BuChE in Wistar rat plasma using acetylthiocholine iodide as substrate after 0.5 hrs by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50388139(CHEMBL2059200)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of BuChE in Wistar rat plasma using acetylthiocholine iodide as substrate after 0.5 hrs by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50388135(CHEMBL2058986)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of BuChE in Wistar rat plasma using acetylthiocholine iodide as substrate after 0.5 hrs by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50388134(CHEMBL2058984)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of BuChE in Wistar rat plasma using acetylthiocholine iodide as substrate after 0.5 hrs by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50388130(CHEMBL2058981)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of BuChE in Wistar rat plasma using acetylthiocholine iodide as substrate after 0.5 hrs by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50388135(CHEMBL2058986)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of BuChE in Wistar rat plasma using acetylthiocholine iodide as substrate after 0.5 hrs by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50388129(CHEMBL2058979)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of BuChE in Wistar rat plasma using acetylthiocholine iodide as substrate after 0.5 hrs by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed